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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:43 PM EDT

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Showing 601–624 of 1,015 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Microbiome Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

A Study of a Baby Wash/Shampoo and Baby Lotion Versus Baby Wash/Shampoo Alone for Impact on Skin Barrier and Microbiome on Newborns

NCT05589038
View directory record Official record
Conditions
Healthy
Interventions
Baby Wash/Shampoo, Baby Lotion
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
0 Days to 28 Days
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newtown Square, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional

Effect of Daily Consumption of Glycomacropeptide on Gut Microbiome and Blood Functional Proteome of Subjects With Irritable Bowel Syndrome

NCT05482464
View directory record Official record
Conditions
Inflammatory Bowel Syndrome
Interventions
Casein glycomacropeptide (CGMP)
Dietary Supplement
Lead sponsor
Oregon State University
Other
Eligibility
18 Years to 30 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Diet and the Gut Microbiome

NCT03269032
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
American Diet, Mediterranean-style Diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption

NCT04066816
View directory record Official record
Conditions
Colo-rectal Cancer, Colon Cancer, Diet Habit
Interventions
Walnuts
Other
Lead sponsor
UConn Health
Other
Eligibility
50 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 26, 2021 · Synced Oct 23, 2026, 8:43 PM EDT
Recruiting Phase 2 Interventional

Combined Oral Contraceptive Pill and Resistance Starch

NCT06852365
View directory record Official record
Conditions
Metabolic Syndrome, Polycystic Ovary Syndrome
Interventions
wheat dextrin, Oral Contraceptives, Low-Dose, Maltodextrin
Dietary Supplement · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 23, 2026, 8:43 PM EDT
Completed No phase listed Observational

Cytokines and Genes in Therapeutic Response in Crohn's Disease

NCT03266471
View directory record Official record
Conditions
Inflammatory Bowel Diseases
Interventions
Baseline blood sample, Baseline intestinal biopsies, Crohn's disease activity index (CDAI), Post treatment blood sample, Post treatment intestinal biopsies, Baseline stool sample, Post treatment stool sample
Diagnostic Test · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 14, 2023 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The RAMP Study - Rejuvenation of the Aging Microbiota With Prebiotics

NCT03690999
View directory record Official record
Conditions
Microbiome, Immune Function, Inflammation
Interventions
Placebo, Prebiotic supplement
Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
60 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2023 · Synced Oct 23, 2026, 8:43 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation

NCT03907501
View directory record Official record
Conditions
Human Microbiome
Interventions
Synbiotic, Probiotic, Placebo
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 23, 2026, 8:43 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

NCT05821309
View directory record Official record
Conditions
Constipation
Interventions
PEG 3350, PEG-3350 with electrolytes, Glycerin
Drug
Lead sponsor
Indiana University
Other
Eligibility
2 Years to 18 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional Results available

Very Low Birth Weight Preterm Infant Bundled Care in the NICU

NCT03370757
View directory record Official record
Conditions
Preterm Infants
Interventions
3-hour bundled care, 6-hour bundled care
Other
Lead sponsor
Duke University
Other
Eligibility
Up to 32 Weeks
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2024 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prebiotic and Probiotic Modulation of the Gut Microbiota-gut-brain Axis During Acute Stress

NCT05392556
View directory record Official record
Conditions
Stress Physiology
Interventions
Probiotic, Prebiotic, Placebo
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 23, 2026, 8:43 PM EDT
Completed No phase listed Observational

Gastrointestinal and Urinary Tract Microbiome After SCI

NCT02903472
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Not listed
Lead sponsor
University of British Columbia
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2021 · Synced Oct 23, 2026, 8:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Agro-ecological Farming Systems on Human Health

NCT05575258
View directory record Official record
Conditions
Inflammatory Response
Interventions
44-Day Diet Conventionally Sourced - YELLOW Diet, 44-Day Diet Agro-Ecologically Sourced - GREEN Diet
Other
Lead sponsor
Utah State University
Other
Eligibility
35 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Oct 23, 2026, 8:43 PM EDT
Terminated Not applicable Interventional

Impact of a Biofeedback Intervention on Microbiome, Metabolome, and Clinical Outcomes in Pediatric IBD (Study 2)

NCT04296110
View directory record Official record
Conditions
IBD
Interventions
Biofeedback, Music Relaxation Therapy
Behavioral · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementing Good Nutrition to Improve, Transform, and Enhance (IGNITE) Firefighters' Health

NCT06567561
View directory record Official record
Conditions
Cancer, Inflammation, Microbiome, Immune Function
Interventions
Whole Foods Plant-Based Diet, Usual Firehouse Diet
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 23, 2026, 8:43 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Association Between Gut Microbiome and Dietary Determinants and Vaccine Response

NCT05239403
View directory record Official record
Conditions
Influenza
Interventions
Biospecimen Collection, Questionnaire Administration
Procedure · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 23, 2026, 8:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Health Effects of Grain Foods in Adults

NCT06339879
View directory record Official record
Conditions
High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar, Low Whole Grain and Low Sugar, Low Whole Grain and High Sugar
Interventions
High Whole Grain, Low Sugar, Low Whole Grain, Low Sugar, High Whole Grain, High Sugar, Low Whole Grain, High Sugar
Other
Lead sponsor
Purdue University
Other
Eligibility
21 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Investigation of the Gut Microbiome and Statin Response

NCT04098003
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Rosuvastatin, Placebo
Drug
Lead sponsor
Sony Tuteja
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Phildelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Mortality Reduction After Oral Azithromycin: Morbidity Study

NCT02048007
View directory record Official record
Conditions
Childhood Mortality
Interventions
Azithromycin, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
1 Month and older
Enrollment
72,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
2
States / cities
San Francisco, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Not applicable Interventional

Microbiome, Exercise Tracking Study: Among Individuals at High Risk for Colorectal Cancer

NCT02780284
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Physical activity intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 69 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Oct 23, 2026, 8:43 PM EDT
Recruiting Phase 2 Interventional

Fecal Microbiome Transplant to Remodel Intestinal Microbiota for Patients With Relapsed or Refractory Lymphoma With Exposure to High-Risk Antibiotics Who Are Receiving Chimeric Antigen Receptor T Cells

NCT07042438
View directory record Official record
Conditions
Recurrent Diffuse Large B-Cell Lymphoma, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions
Axicabtagene Ciloleucel, Biospecimen Collection, Chemotherapy, Fecal Microbiota Transplantation, Leukapheresis, Placebo Administration
Biological · Procedure · Drug
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 23, 2026, 8:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Farms, Animals and Adolescents: Reinforcing the Microbiome

NCT03189849
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
7 Years to 13 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 23, 2026, 8:43 PM EDT
Completed Phase 4 Interventional

NICU Antibiotics and Outcomes Trial

NCT03997266
View directory record Official record
Conditions
Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Interventions
Ampicillin, Gentamycin, Normal saline
Drug
Lead sponsor
Michael Morowitz
Other
Eligibility
Up to 4 Hours
Enrollment
359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
14
States / cities
Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 23, 2026, 8:43 PM EDT
Recruiting Early Phase 1 Interventional

Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation

NCT07308808
View directory record Official record
Conditions
Spinal Cord Injuries (SCI), Neurogenic Bladder, Urinary Tract Infection (Diagnosis)
Interventions
Lactobacillus Crispatus, Saline bladder wash
Drug · Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Oct 23, 2026, 8:43 PM EDT