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ClinicalTrials.gov public records Last synced Oct 24, 2026, 5:38 PM EDT

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Showing 745–768 of 1,015 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Microbiome Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cinnamon Spice on Glucose Tolerance in Subjects With Pre-diabetes

NCT04342624
View directory record Official record
Conditions
PreDiabetes, Blood Glucose, High
Interventions
Cinnamon, Placebo
Dietary Supplement · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
20 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety, Tolerability, and Biosignature of Humanized Prebiotics in Healthy Adults

NCT06068894
View directory record Official record
Conditions
Intestinal Health
Interventions
"Humanized" galacto-oligosaccharides (hGOS), Galacto-oligosaccharides (GOS), Matching Placebo
Dietary Supplement · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 24, 2026, 5:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Microbiome of Donor Iron Deficient Study

NCT02990988
View directory record Official record
Conditions
Iron Deficiency
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional

Precision Pain Self-Management in Young Adults With Irritable Bowel Syndrome

NCT03332537
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Personalized IBS Pain SM
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 29 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Farmington, Connecticut • Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Gut-level Antiinflammatory Activities of Green Tea in Metabolic Syndrome

NCT03973996
View directory record Official record
Conditions
Dysbiosis, Endotoxemia, Metabolic Syndrome, Inflammation
Interventions
Green Tea Extract, Placebo
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 24, 2026, 5:38 PM EDT
Recruiting Phase 2 Interventional

Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer

NCT05462496
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Biopsy, FOLFIRINOX, Ciprofloxacin, Metronidazole, Pembrolizumab, Surgical Resection
Procedure · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional

Esophageal Atresia: a Natural Experiment of the Effects of Oral Inoculation on the Gut Microbiome

NCT04901546
View directory record Official record
Conditions
Esophageal Atresia
Interventions
Patient's own saliva
Other
Lead sponsor
Stanford University
Other
Eligibility
Up to 3 Months
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 24, 2026, 5:38 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Gut Microbiomes in HD

NCT06448546
View directory record Official record
Conditions
Huntington Disease
Interventions
Not listed
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Oct 24, 2026, 5:38 PM EDT
Completed No phase listed Observational

Gut and Intratumoral Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer

NCT03586297
View directory record Official record
Conditions
Triple Negative Breast Cancer
Interventions
Not listed
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
3
States / cities
New Haven, Connecticut • Washington D.C., District of Columbia • Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fiber Effectively Educates & Directs the Microbiome Study

NCT06395324
View directory record Official record
Conditions
Microbial Colonization
Interventions
High arabinose diet
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Oct 24, 2026, 5:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ocular Surface Microbiome

NCT02298881
View directory record Official record
Conditions
Dry Eye Syndromes
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 24, 2026, 5:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Microbiomes of Pelvic Pain

NCT01738464
View directory record Official record
Conditions
Interstitial Cystitis, Chronic Prostatitis, Chronic Pelvic Pain Syndrome, Lower Urinary Tract Symptoms, Overactive Bladder, Major Depression
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Oct 24, 2026, 5:38 PM EDT
Not listed No phase listed Observational

Microbiome in Immunotherapy naïve NSCLC Patients Receiving PD-1/L1 Blockade (MIP_NSCLC)

NCT04636775
View directory record Official record
Conditions
NSCLC Stage IV, NSCLC, Recurrent
Interventions
Microbiome
Diagnostic Test
Lead sponsor
Jun Zhang, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
3
States / cities
Fairway, Kansas • Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Oct 24, 2026, 5:38 PM EDT
Recruiting No phase listed Observational

Microbiome Determinants of Adverse Effects of Stereotactic Radiosurgery

NCT07767981
View directory record Official record
Conditions
Adverse Radiation Effects, Radiation Necrosis
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 24, 2026, 5:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters

NCT07846371
View directory record Official record
Conditions
Environmental Exposure, PFAS Exposure
Interventions
Streptococcus salivarius 46-SL1, Placebo
Dietary Supplement
Lead sponsor
Cambiotics ApS
Industry
Eligibility
18 Years and older · Male only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 24, 2026, 5:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Tissue Destruction and Healing in Celiac Disease

NCT05680012
View directory record Official record
Conditions
Celiac Disease
Interventions
Gluten containing snack bar
Dietary Supplement
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
3
States / cities
Pasadena, California • Chicago, Illinois • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional

Efficacy and Tolerability of a Scalp Serum

NCT07500623
View directory record Official record
Conditions
Hair Thinning
Interventions
Scalp Serum
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
25 Years to 65 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Broomall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Peanuts and Glycemic Control

NCT03654651
View directory record Official record
Conditions
Type2 Diabetes, Cardiovascular Diseases
Interventions
Peanut, High carbohydrate snack
Drug
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2023 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Stool Microbiome Using HyGIeaCare Prep

NCT04264923
View directory record Official record
Conditions
Stool Microbiome
Interventions
HyGIeaCare Prep
Other
Lead sponsor
HyGIeaCare, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 24, 2026, 5:38 PM EDT
Enrolling by invitation No phase listed Observational

Pilot Study to Characterize the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of CLn® Skin Care Body Wash

NCT06665490
View directory record Official record
Conditions
Cutaneous T Cell Lymphoma
Interventions
CLn Body Wash
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Flourish Vaginal Care System to Establish Neovaginal Microbiome

NCT05372770
View directory record Official record
Conditions
Neovaginal Microbiome
Interventions
Flourish Vaginal Care system
Device
Lead sponsor
Vaginal Biome Science
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Hope, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 24, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Glycomacropeptide and Women's Health

NCT05551091
View directory record Official record
Conditions
Obesity
Interventions
glycomacropeptide (GMP)
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Up to 90 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Oct 24, 2026, 5:38 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Prophylactic Antibiotics Prior to Embryo Transfer (PAPET): RCT

NCT03386227
View directory record Official record
Conditions
Assisted Reproductive Technology, Antibiotic Prophylaxis, Embryo Transfer
Interventions
Withholding antibiotic prophylaxis
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 43 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Oct 24, 2026, 5:38 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Postcoital Sponge on Self-Reported Vaginal Health Parameters

NCT06530186
View directory record Official record
Conditions
Vaginal Infection, Vaginal Discharge, Vaginosis, Sexual Dysfunction
Interventions
LiviWell Postcoital Vaginal Insert
Device
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Mountain Lakes, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Oct 24, 2026, 5:38 PM EDT