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ClinicalTrials.gov public records Last synced Oct 19, 2026, 8:03 AM EDT

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Showing 1–24 of 72 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Microbiome analysis Clear all
Completed Phase 2 Interventional Results available

Antibiotic "Dysbiosis" in Preterm Infants

NCT02784821
View directory record Official record
Conditions
Enterocolitis, Necrotizing, Bacteremia, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Periventricular Leukomalacia, Chronic Lung Disease, Ileal Perforation
Interventions
Antibiotic, Gastric fluid, Breast milk, Stool samples, Antibiotics
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
23 Weeks to 33 Weeks
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 19, 2026, 8:03 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Recurrent Urinary Tract Infections and the Microbiome

NCT04831840
View directory record Official record
Conditions
Recurrent Urinary Tract Infection
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Fort Lauderdale, Florida • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 19, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

Engagement of American Indians of Southwestern Tribal Nations in Cancer Genome Sequencing

NCT06207864
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
Biospecimen Collection, Return of Results, Survey Administration
Procedure · Other
Lead sponsor
New Mexico Cancer Research Alliance
Other
Eligibility
18 Years and older
Enrollment
1,001 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 19, 2026, 8:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Acne Vulgaris Related Microbiology and Serology

NCT04056598
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Study of humoral immunity
Diagnostic Test
Lead sponsor
Sanofi
Industry
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Characterizing Skin Microbiome Change in Atopic Dermatitis

NCT04800185
View directory record Official record
Conditions
Atopic Dermatitis, Atopic Dermatitis Eczema
Interventions
Crisaborole 2% Top Oint, Skin Microbiome Swabs
Drug · Genetic
Lead sponsor
University of California, Irvine
Other
Eligibility
2 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers

NCT02439255
View directory record Official record
Conditions
Healthy Subject, Tobacco Use Disorder
Interventions
Laboratory Biomarker Analysis, Phytochemical, Placebo, Screening Questionnaire Administration
Other · Dietary Supplement
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 50 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Oct 19, 2026, 8:03 AM EDT
Active, not recruiting No phase listed Observational

Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes

NCT02371135
View directory record Official record
Conditions
Lynch Syndrome, Hereditary Colonic Polyposis Syndromes
Interventions
colonic biopsies, questionnaires
Genetic
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional

Comparing the Effectiveness of 2 Diets for Patients With Irritable Bowel Syndrome

NCT01624610
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Dietary intervention
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 19, 2026, 8:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of a Microbiome Non-invasive Diagnosis Tool

NCT03330444
View directory record Official record
Conditions
Infertility of Uterine Origin
Interventions
Endometrial biopsy and endometrial fluid collection
Procedure
Lead sponsor
Igenomix
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
4
States / cities
Norwalk, Connecticut • Margate, Florida • Chesterfield, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2020 · Synced Oct 19, 2026, 8:03 AM EDT
Completed No phase listed Observational

Microbiome in Lung Cancer and Other Malignancies

NCT03688347
View directory record Official record
Conditions
Lung Cancer, Cancer, Malignancy
Interventions
Nasal Swab, Oral Swab, Stool Collection, Microbiome analysis, DNA Banking, Skin Swab
Procedure · Other · Genetic
Lead sponsor
Taher Abu Hejleh
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Early Phase 1 Interventional

Rifaximin for Infection Prophylaxis in Hematopoietic Stem Cell Transplantation

NCT03529825
View directory record Official record
Conditions
Microbial Colonization
Interventions
Rifaximin
Drug
Lead sponsor
Emory University
Other
Eligibility
2 Years to 21 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 19, 2026, 8:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Microbiome and Axial Spondyloarthritis

NCT04713995
View directory record Official record
Conditions
Axial Spondyloarthritis
Interventions
Dietary recommendations
Other
Lead sponsor
Viome
Industry
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 19, 2026, 8:03 AM EDT
Terminated Phase 2 Interventional

Gluten Free Diet in Diminishing Side Effects Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy

NCT03108911
View directory record Official record
Conditions
Acute Myeloid Leukemia
Interventions
Best Practice, Biospecimen Collection, Dietary Intervention, Laboratory Biomarker Analysis
Other · Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Oct 19, 2026, 8:03 AM EDT
Completed No phase listed Observational

Microbiome and Immunologic Analysis - Women With Endometriosis

NCT04159740
View directory record Official record
Conditions
Endometriosis
Interventions
Tissue and blood collection
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 19, 2026, 8:03 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Sample Collection From Healthy Volunteers for Assay Optimization

NCT03538600
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
3 Years to 80 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2043
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Analyzing IBS to Identify Biomarkers and Microbiome Signatures

NCT02419963
View directory record Official record
Conditions
Diarrhoea Predominant Irritable Bowel Syndrome, IBS
Interventions
endoscopy for tissue biopsy, Blood Sample, Stool Sample
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 19, 2026, 8:03 AM EDT
Active, not recruiting Not applicable Interventional

Probiotics in Adults With Rheumatoid Arthritis

NCT07304505
View directory record Official record
Conditions
Rheumatoid Arthritis (RA)
Interventions
Align Extra Strength Probiotic Supplement
Dietary Supplement
Lead sponsor
Ancilia Biosciences
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Completed No phase listed Observational

Prevalence of Multidrug Resistant Micro-organism Carriage in Patients Undergoing an ERCP in Four Different Countries

NCT05303662
View directory record Official record
Conditions
Drug Resistance, Multiple, Bacterial, Cholangiopancreatography, Endoscopic Retrograde
Interventions
Multidrug-Resistant Organisms (MDRO) testing through rectal and oral/nasal swabs, MDRO-testing duodenal aspirate, Microbiome through rectal swab, Microbiome testing duodenal aspirate
Diagnostic Test
Lead sponsor
Marco J. Bruno
Other
Eligibility
18 Years and older
Enrollment
1,244 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 8, 2025 · Synced Oct 19, 2026, 8:03 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Mechanisms of Post-Bariatric Hypoglycemia

NCT04428866
View directory record Official record
Conditions
Hypoglycemia
Interventions
Continuous Glucose Monitoring, activity monitor, Mixed meal tolerance test, Glucagon Sensitivity Testing, Hypoglycemic Hyperinsulinemic Clamp, analysis of fecal microbiome
Diagnostic Test
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 19, 2026, 8:03 AM EDT
Completed No phase listed Observational

Study Assessing Risk Factors for Abdominal Pain in Children With Inflammatory Bowel Disease

NCT02984059
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
Genomic DNA, RNA analysis, Microbiome, Calprotectin, Pain questionnaires, Anxiety/Depression Questionnaires
Genetic · Other
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
8 Years to 18 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 8, 2019 · Synced Oct 19, 2026, 8:03 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Ocular Surface Dry Eye Microbiome

NCT02306668
View directory record Official record
Conditions
Dry Eyes
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 3, 2014 · Synced Oct 19, 2026, 8:03 AM EDT
Suspended No phase listed Observational

Role of Pancreatic Exocrine Secretion in Weight Gain After Pancreas Transplantation

NCT04690738
View directory record Official record
Conditions
Exocrine Pancreatic Insufficiency, Weight Gain
Interventions
Fecal Elastase Concentration
Diagnostic Test
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 19, 2026, 8:03 AM EDT
Recruiting No phase listed Observational

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

NCT06009276
View directory record Official record
Conditions
Heart Failure, Systolic, Heart Failure, Diastolic, Peripheral Arterial Disease, Overweight and Obesity
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
70 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 19, 2026, 8:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Oral Microbiome and Upper Aerodigestive Squamous Cell Cancer

NCT03304132
View directory record Official record
Conditions
Oral Cancer
Interventions
Classification of Oral Microbiome Using 16S rRNA gene sequence-based approach, Classification of Oral Microbiome Using taxonomic approach
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years to 92 Years
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Oct 19, 2026, 8:03 AM EDT