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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Microneedling Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

SkinPen Efficacy on Acne Scars on the Face and/or Back

NCT02646917
View directory record Official record
Conditions
Atrophic Acne Scar
Interventions
Aesthetic Microneedling Treatment
Procedure
Lead sponsor
Bellus Medical, LLC
Industry
Eligibility
18 Years to 60 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radio Frequency Microneedling for Suprapatellar Skin

NCT03507036
View directory record Official record
Conditions
Skin Laxity
Interventions
Profound system
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RF Microneedling With Multi-Depth Targeting Per Insertion for The Treatment of Cellulite

NCT06283056
View directory record Official record
Conditions
Cellulitis of Leg
Interventions
Device treatment
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
New York, New York • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 2, 2026, 1:52 AM EDT
Active, not recruiting Not applicable Interventional

Efficacy and Safety of TargetCool + Benev Exosomes in Patients With Hair Thinning

NCT06999408
View directory record Official record
Conditions
Hair Diseases, Alopecia, Hair Thinning
Interventions
Scalp tattoo, Canfield HairMetrix®, TargetCool, Microneedle-facilitated lidocaine application
Device
Lead sponsor
Recens Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Follicular Revival in Treatment-resistant Alopecia Areata: Evaluating Use of Micro-needling

NCT04338295
View directory record Official record
Conditions
Alopecia Areata
Interventions
Tattoo machine (SOL Nova Device)
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color.

NCT06616311
View directory record Official record
Conditions
Melasma
Interventions
Radiofrequency microneedling
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 2, 2026, 1:52 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Efficacy and Tolerability of the SkinPen on Male and Female Subjects' Dorsal Hands as a Treatment for Signs of Hand Aging

NCT04136847
View directory record Official record
Conditions
Aging
Interventions
SkinPen Precision
Device
Lead sponsor
Bellus Medical, LLC
Industry
Eligibility
50 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2021 · Synced Sep 2, 2026, 1:52 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Evaluating Microneedling With CBD and Hempseed Oil for Acne Vulgaris Safety and Efficacy

NCT06362889
View directory record Official record
Conditions
Acne Vulgaris (Disorder)
Interventions
Microneedling with CBD
Combination Product
Lead sponsor
Rejuva Medical Aesthetics
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment Skin Quality and Efficacy of Dermal Line After Four Bipolar Radiofrequency Microneedling Treatments

NCT05085730
View directory record Official record
Conditions
Aging
Interventions
InMode Morpheus8 System
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Sep 2, 2026, 1:52 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Efficacy and Safety Of AGE ZERO™ EXOSOMES To Treat Men and Women With Androgenetic Alopecia

NCT06482541
View directory record Official record
Conditions
Androgenetic Alopecia
Interventions
5 billion exosomes and saline solution microneedling, 50 billion exosomes and saline solution microneedling
Combination Product
Lead sponsor
Levit Dermatology
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars

NCT02643628
View directory record Official record
Conditions
Atrophic Acne Scars
Interventions
Microneedling, Microneedling followed by Bellafill treatment
Procedure · Device
Lead sponsor
Suneva Medical, Inc.
Industry
Eligibility
21 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 27, 2019 · Synced Sep 2, 2026, 1:52 AM EDT
Recruiting Not applicable Interventional

Microneedling vs Dermabrasion for Early Facial Scar Resurfacing

NCT06171386
View directory record Official record
Conditions
Scar
Interventions
Microneedling, Dermabrasion
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 2, 2026, 1:52 AM EDT
Recruiting Phase 4 Interventional

Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

NCT07225348
View directory record Official record
Conditions
Perioral Wrinkles
Interventions
Poly-L-Lactic Acid, Microneedling
Drug · Device
Lead sponsor
Skincare Physicians of Chestnut Hill
Other
Eligibility
40 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Phase 1 Interventional Results available

Phase I Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)

NCT01682811
View directory record Official record
Conditions
Neurofibromatoses
Interventions
Part 1 Levulan injection, Part 1 Levulan surface application, Part 1 Levulan surface application twice, Part 1 Levulan surface application twice with microneedling, Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 1, Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 2, Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 3
Drug
Lead sponsor
Harry T Whelan, MD
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 2, 2026, 1:52 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Split Face Study of the Effects of Micro Needling With and Without Platelet Rich Plasma

NCT04219293
View directory record Official record
Conditions
Aging
Interventions
Microneedling w/ and w/o PRP
Device
Lead sponsor
Dallas Plastic Surgery Institute
Other
Eligibility
30 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional

Microneedling Plus the Universal Peel For Acne Scarring

NCT02174393
View directory record Official record
Conditions
Acne Scarring
Interventions
Universal Peel, Microneedling, Post-Microneedling Skin Care, Post-Universal Peel Skin Care
Drug · Procedure
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Englewood Cliffs, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Straberi Microneedling For Atrophic Acne

NCT04740268
View directory record Official record
Conditions
Atrophic Acne Scar
Interventions
Straberi
Device
Lead sponsor
Universal Skincare Institute
Other
Eligibility
21 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional

A Proof of Concept Study to Evaluate the Efficacy and Tolerability of Microneedling With SkinPen in Female and Male Subjects With Facial Acne Vulgaris, Ages 18 Through 45

NCT05071274
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Skinpen Prescision System
Device
Lead sponsor
Crown Laboratories, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2022 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Efficacy and Safety of the Skinstylus Sterilock Microneedling System for the Treatment of Facial Wrinkles

NCT06032286
View directory record Official record
Conditions
Subjects Displaying Facial Ageing
Interventions
Skinstylus microneedling device
Device
Lead sponsor
Beauty Health
Industry
Eligibility
35 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Manhattan Beach, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Straberi Epistamp Needling Treatment For Skin Rejuvenation

NCT04742803
View directory record Official record
Conditions
Wrinkle, Elastic Skin, Collagen Degeneration
Interventions
Straberi Epistamp Microneedling Treatment
Device
Lead sponsor
Universal Skincare Institute
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 2, 2026, 1:52 AM EDT
Enrolling by invitation Not applicable Interventional

Pilot Study to Evaluate the Efficacy and Safety of Xvie Delivered Into the Scalp by Microneedling in Women With Self-perceived Thinning Hair

NCT07221773
View directory record Official record
Conditions
Hair Thinning
Interventions
XVIE
Other
Lead sponsor
Restore Biologics Holdings, Inc. dba Xtressé
Industry
Eligibility
28 Years to 65 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Maitland, Florida • Marriottsville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Follicular Revival in Androgenic Alopecia: Evaluating Use of Micro-needling

NCT04341363
View directory record Official record
Conditions
Androgenic Alopecia
Interventions
Tattoo machine
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Sep 2, 2026, 1:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation

NCT06157853
View directory record Official record
Conditions
Photoaging, Wrinkle
Interventions
Radiofrequency Microneedling, Facial Cleanser, Facial Moisturizer, Sunscreen
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2024 · Synced Sep 2, 2026, 1:52 AM EDT
Not listed Not applicable Interventional

Clinical Study to Evaluate Different Energy-based Devices for Aesthetic Treatments.

NCT06111482
View directory record Official record
Conditions
Dermatologic Conditions
Interventions
Intense pulsed light., Radiofrequency microneedling device, Radiofrequency device, Combined energy devices
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Westford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Sep 2, 2026, 1:52 AM EDT