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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Microneedling device Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Follicular Revival in Treatment-resistant Alopecia Areata: Evaluating Use of Micro-needling

NCT04338295
View directory record Official record
Conditions
Alopecia Areata
Interventions
Tattoo machine (SOL Nova Device)
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SkinPen Efficacy on Acne Scars on the Face and/or Back

NCT02646917
View directory record Official record
Conditions
Atrophic Acne Scar
Interventions
Aesthetic Microneedling Treatment
Procedure
Lead sponsor
Bellus Medical, LLC
Industry
Eligibility
18 Years to 60 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 5, 2026, 4:24 PM EDT
Recruiting Not applicable Interventional

Rosacea Radiofrequency Microneedling

NCT06801717
View directory record Official record
Conditions
Rosacea, Papulopustular, Rosacea, Erythematotelangiectatic
Interventions
KTP Laser Therapy, Radiofrequency microneedling
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Miami Beach, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Recruiting Phase 4 Interventional

Treatment of Perioral Wrinkles Using Topical Poly-L-lactic Acid and Microneedling Device

NCT07225348
View directory record Official record
Conditions
Perioral Wrinkles
Interventions
Poly-L-Lactic Acid, Microneedling
Drug · Device
Lead sponsor
Skincare Physicians of Chestnut Hill
Other
Eligibility
40 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Follicular Revival in Fibrosing Alopecia: Evaluating Use of Micro-needling

NCT04342091
View directory record Official record
Conditions
Fibrosing Alopecia, Frontal Fibrosing Alopecia, Central Centrifugal Cicatricial Alopecia
Interventions
SOL Nova Device
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Sep 5, 2026, 4:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Sylfirm X Radiofrequency Microneedling for the Treatment of Melasma

NCT06415435
View directory record Official record
Conditions
Melasma
Interventions
Radiofrequency Microneedling
Device
Lead sponsor
Benev Company, Inc.
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
La Jolla, California • Charlotte, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 5, 2026, 4:24 PM EDT
Not yet recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

A Full Face Study to Evaluate the Efficacy of Dermapen 4™ Microneedling Device in Addition with MG-CLR Serum for Acne Treatment Over 12 Weeks.

NCT06602284
View directory record Official record
Conditions
Acne
Interventions
Dermapen 4™
Combination Product
Lead sponsor
Equipmed USA LLC
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Straberi Microneedling For Atrophic Acne

NCT04740268
View directory record Official record
Conditions
Atrophic Acne Scar
Interventions
Straberi
Device
Lead sponsor
Universal Skincare Institute
Other
Eligibility
21 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Results available

Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device

NCT05254210
View directory record Official record
Conditions
Wrinkles, Fine Lines, Crepey Skin, Acne Scars, Active Acne, Enlarged Pores, Loose Skin
Interventions
RF Device (Potenza™)
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 5, 2026, 4:24 PM EDT
Not listed Not applicable Interventional

Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions

NCT05987319
View directory record Official record
Conditions
Wrinkle, Fine Lines, Crepey Skin, Acne Scars, Active Acne, Enlarged Pores, Stretch Mark, Loose Skin
Interventions
RadioFrequency Microneedling Device
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Westford, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 5, 2026, 4:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Radio-Frequency Microneedling Device

NCT06228144
View directory record Official record
Conditions
Healthy
Interventions
Candela Profound System with Dermal Handpiece, Experimental Dermal Cooling Device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars

NCT02643628
View directory record Official record
Conditions
Atrophic Acne Scars
Interventions
Microneedling, Microneedling followed by Bellafill treatment
Procedure · Device
Lead sponsor
Suneva Medical, Inc.
Industry
Eligibility
21 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 27, 2019 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin

NCT03380845
View directory record Official record
Conditions
Acne Scars
Interventions
Fraxel Restore, Fractora
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Clinical Efficacy And Safety Of SkinStylus Microneedling System

NCT03366194
View directory record Official record
Conditions
Cicatrix, Hypertrophic
Interventions
SkinStylus Sterilock System
Device
Lead sponsor
Esthetic Education LLC
Industry
Eligibility
23 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Follicular Revival in Androgenic Alopecia: Evaluating Use of Micro-needling

NCT04341363
View directory record Official record
Conditions
Androgenic Alopecia
Interventions
Tattoo machine
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Sep 5, 2026, 4:24 PM EDT
Not listed Not applicable Interventional

Clinical Study to Evaluate Different Energy-based Devices for Aesthetic Treatments.

NCT06111482
View directory record Official record
Conditions
Dermatologic Conditions
Interventions
Intense pulsed light., Radiofrequency microneedling device, Radiofrequency device, Combined energy devices
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Westford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Sep 5, 2026, 4:24 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Evaluating Microneedling With CBD and Hempseed Oil for Acne Vulgaris Safety and Efficacy

NCT06362889
View directory record Official record
Conditions
Acne Vulgaris (Disorder)
Interventions
Microneedling with CBD
Combination Product
Lead sponsor
Rejuva Medical Aesthetics
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 5, 2026, 4:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars

NCT03901417
View directory record Official record
Conditions
Acne Scars
Interventions
Fraxel Restore (Non-ablative Fractional Laser), Fraxel Restore (Non-ablative fractional laser) and SkinPen (Microneedling Device)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional

Microneedling Plus the Universal Peel For Acne Scarring

NCT02174393
View directory record Official record
Conditions
Acne Scarring
Interventions
Universal Peel, Microneedling, Post-Microneedling Skin Care, Post-Universal Peel Skin Care
Drug · Procedure
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Englewood Cliffs, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment

NCT04738149
View directory record Official record
Conditions
Vitiligo
Interventions
Bimatoprost, Excimer laser, Microneedling with a dermaroller
Drug · Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Results available

Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions

NCT05097157
View directory record Official record
Conditions
Wrinkle, Fine Lines, Crepey Skin, Acne Scars, Acne, Enlarged Pores, Stretch Marks, Loose Skin
Interventions
Potenza
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Sacramento, California • Hunt Valley, Maryland • Westford, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RF Microneedling With Multi-Depth Targeting Per Insertion for The Treatment of Cellulite

NCT06283056
View directory record Official record
Conditions
Cellulitis of Leg
Interventions
Device treatment
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
New York, New York • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 5, 2026, 4:24 PM EDT
Withdrawn Not applicable Interventional

Acne Scarring in Skin of Color: Laser vs Microneedling

NCT03395678
View directory record Official record
Conditions
Acne Vulgaris, Scar
Interventions
Microneedling, Fractional non-ablative 1,540nm laser
Device
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Sep 5, 2026, 4:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radio Frequency Microneedling for Suprapatellar Skin

NCT03507036
View directory record Official record
Conditions
Skin Laxity
Interventions
Profound system
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Sep 5, 2026, 4:24 PM EDT