- Conditions
- Amatoxin Poisoning, Amanita Poisoning, Mushroom Poisoning, Liver Failure
- Interventions
- Silibinin
- Drug
- Lead sponsor
- Mylan Specialty, LP
- Industry
- Eligibility
- Not listed
- Enrollment
- 148 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2020
- U.S. locations
- 2
- States / cities
- Somerset, New Jersey • Morgantown, West Virginia
Search Results
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Showing 1–24
of 30
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Obesity
- Interventions
- Milk Thistle (MT), Lactobacillus Gasseri (LAC), Exercise (EX), Control (CON)
- Dietary Supplement · Behavioral
- Lead sponsor
- Kyle Flack
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Healthy
- Interventions
- Product B® IsaGenesis®, IsaGenesis®
- Dietary Supplement
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Amyotrophic Lateral Sclerosis ALS
- Interventions
- Astaxanthin, Protandim, Melatonin, MitoQ
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Philadelphia, Pennsylvania
- Conditions
- Atopic Asthma
- Interventions
- Oral Silymarin, Oral Silymarin, maintenance dose, Placebo
- Drug
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Diabetic Nephropathies, Proteinuria, Oxidative Stress
- Interventions
- N-acetylcysteine, silibin, high-dose silibin, N-acetylcysteine placebo, silibin placebo
- Dietary Supplement
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 114 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2016
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Chronic Hepatitis C, Oxidative Stress
- Interventions
- silymarin, green tea extract (EGCG)
- Drug · Dietary Supplement
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Metabolic Syndrome
- Interventions
- Protandim
- Dietary Supplement
- Lead sponsor
- SomaLogic, Inc.
- Industry
- Eligibility
- 40 Years to 60 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Non-Alcoholic Fatty Liver Disease (NAFLD)
- Interventions
- Milk thistle (MT), Placebo, Lifestyle Modification, Fibroscan
- Drug · Behavioral · Device
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- 9 Years to 22 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Trichotillomania, Hair Pulling Disorder
- Interventions
- Milk Thistle, Placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 10 Years to 65 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- HIV Infections, Hepatitis C
- Interventions
- Silymarin, Placebo
- Drug
- Lead sponsor
- Henry Sacks
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Hyperoxaluria
- Interventions
- Aloe vera with cactus, Cranberry, Green tea extract, Bilberry, Cinnamon, Milk thistle, Turmeric, Aloe vera
- Dietary Supplement
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Oxidative Stress
- Interventions
- Protandim Dietary Supplement, Placebo Group
- Dietary Supplement · Other
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Constipation, Bloating
- Interventions
- Dietary supplement for digestive health, placebo capsule
- Dietary Supplement
- Lead sponsor
- University of Memphis
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Prostate Cancer
- Interventions
- Silibin-Phytosome
- Drug
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Non-alcoholic Steatohepatitis
- Interventions
- Placebo, Silymarin 700 mg, Silymarin 420 mg
- Other · Drug
- Lead sponsor
- Madaus Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 6
- States / cities
- Boston, Massachusetts • Chapel Hill, North Carolina • Philadelphia, Pennsylvania + 2 more
- Conditions
- Acne, Premenstrual Syndrome
- Interventions
- Skincare Routine, MINDBODYSKIN Supplement
- Other · Dietary Supplement
- Lead sponsor
- Clearstem Skincare
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Santa Monica, California
- Conditions
- Diabetic Nephropathy, Proteinuria, Oxidative Stress
- Interventions
- N-acetylcysteine placebo and silibin placebo, N-acetylcysteine active and silibin placebo, N-acetylcysteine placebo and silibin active, N-acetylcysteine active and silibin active, N-acetylcysteine active + high-dose silibin active
- Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 76 Years
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Healthy
- Interventions
- Not listed
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Advanced Hepatocellular Carcinoma
- Interventions
- Silybin
- Drug
- Lead sponsor
- Abby Siegel
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Small Intestinal Bacterial Overgrowth
- Interventions
- Novel Supplement Based Therapy
- Dietary Supplement
- Lead sponsor
- Atrium Innovations
- Industry
- Eligibility
- 19 Years to 84 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Oxford, Ohio
- Conditions
- PMS, Menstrual Cramp, Mood Change
- Interventions
- PMS Capsule, Capsule Placebo, PMS Gummy, Gummy Placebo
- Dietary Supplement
- Lead sponsor
- Semaine Health
- Industry
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 176 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Body Dysmorphic Disorder
- Interventions
- Milk Thistle, Placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2023
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- HIV Infection, Healthy
- Interventions
- Silymarin (milk thistle)
- Drug
- Lead sponsor
- National Institutes of Health Clinical Center (CC)
- NIH
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2001
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland