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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Mindfulness-Oriented Recovery Enhancement Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Smoking Cessation Behavioral Treatment Study

NCT03948893
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Mindfulness-Oriented Recovery Enhancement (MORE), Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Columbia, Missouri • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Sep 23, 2026, 11:08 PM EDT
Suspended Not applicable Interventional

Mindfulness Intervention for Individuals With HIV and Chronic Pain

NCT06481501
View directory record Official record
Conditions
Chronic Pain, HIV Infections
Interventions
ONE Mindfulness-Oriented Recovery Enhancement
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction

NCT04112186
View directory record Official record
Conditions
Opiate Use Disorder
Interventions
Behavioral group therapy #1, Behavioral group therapy #2
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 23, 2026, 11:08 PM EDT
Recruiting Phase 1 Interventional

Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder

NCT06642181
View directory record Official record
Conditions
Mindfulness, Guanfacine, Opioid Use Disorder
Interventions
Guanfacine pharmacotherapy, Mindfulness Oriented Recovery Enhancement (MORE)
Drug · Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 55 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional

One MORE for Chronic Pain

NCT05194241
View directory record Official record
Conditions
Chronic Pain
Interventions
One MORE
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Sep 23, 2026, 11:08 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief

NCT05877521
View directory record Official record
Conditions
Chronic Pain, Cancer Pain
Interventions
MORE treatments, Standard of Care for Pain Management
Behavioral · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 23, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

This Project is a Three-arm RCT Evaluating Two, Single-session Behavioral Interventions for Adults With Chronic Musculoskeletal Pain (CMP) -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE) vs. Empowered Relief (ER) -- Relative to the Traditional 8-week Version of MORE.

NCT07193095
View directory record Official record
Conditions
Chronic Musculoskeletal Pain
Interventions
Brief Mindfulness Oriented Recovery Enhancement, Empowered Relief, Mindfulness Oriented Recovery Enhancement
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Pilot of Mindfulness Oriented Recovery Enhancement in MethadoneTreatment

NCT03894501
View directory record Official record
Conditions
Opioid Use, Chronic Pain
Interventions
Mindfulness Oriented Recovery Enhancement, Methadone program behavioral treatment as usual
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Impact of Mindfulness Training on Adolescent Well-Being and Behavior

NCT05537961
View directory record Official record
Conditions
Substance Use, Mindfulness, Psychological Well-being
Interventions
Mindfulness-Oriented Recovery Enhancement
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
15 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 23, 2026, 11:08 PM EDT
Not listed Not applicable Interventional

Treating Opioid Misuse Via Mindfulness-Based Just-in-Time Adaptive Intervention

NCT04567043
View directory record Official record
Conditions
Chronic Pain
Interventions
MORE+JITAI, Supporive Psychotherapy
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 4, 2023 · Synced Sep 23, 2026, 11:08 PM EDT
Terminated Not applicable Interventional

Mindfulness Oriented Recovery Enhancement in Hospitalized People With Opioid Use Disorder

NCT05066321
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Mindfulness Oriented Recovery Enhancement Sessions
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 23, 2026, 11:08 PM EDT
Recruiting Phase 3 Interventional

Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement

NCT06033599
View directory record Official record
Conditions
Polysubstance Abuse, Opioid Use, Tobacco Use
Interventions
MORE and MI and NRT, MORE and No MI and NRT, Support Group and MI and NRT, Support Group and No MI and NRT
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
New Brunswick, New Jersey • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 23, 2026, 11:08 PM EDT
Not yet recruiting Phase 2 Interventional

Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement

NCT07369089
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Ketamine, Mindfulness-Oriented Recovery Enhancement (MORE), Support Group
Drug · Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
La Jolla, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Optimize Low Back Pain

NCT03859713
View directory record Official record
Conditions
Low Back Pain, Chronic Pain
Interventions
Physical Therapy, Cognitive Behavioral Therapy, Mindfulness, Phase I Treatment, Phase II Switching
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 64 Years
Enrollment
749 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
Baltimore, Maryland • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 23, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

Brief Mindfulness-Oriented Recovery Enhancement vs Brief Cognitive-Behavioral Therapy for Chronic Pain

NCT07207174
View directory record Official record
Conditions
Chronic Pain
Interventions
Brief Mindfulness Oriented Recovery Enhancement, Brief Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 23, 2026, 11:08 PM EDT
Terminated Not applicable Interventional Results available

A Pilot Feasibility Study of Mindfulness-Oriented Recovery Enhancement With Pregnant Women With Opioid Use Disorder

NCT04824521
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Mindfulness-Oriented Recovery Enhancement
Behavioral
Lead sponsor
University of Montana
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Jan 15, 2024 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Mindfulness Oriented Recovery Enhancement for Chronic Pain and Opioid Relapse

NCT04491968
View directory record Official record
Conditions
Opioid Use, Chronic Pain
Interventions
Mindfulness Oriented Recovery Enhancement, Methadone Treatment as Usual
Behavioral · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Behavioral Interventions for Chronic Pain and Opioid-Related Problems

NCT03298269
View directory record Official record
Conditions
Chronic Pain
Interventions
Mindfulness-Oriented Recovery Enhancement, Supportive Counseling
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 100 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Sep 23, 2026, 11:08 PM EDT
Terminated Not applicable Interventional

Effects of Behavioral Interventions on Mechanisms of Pain Regulation and Hedonic Regulation

NCT02935465
View directory record Official record
Conditions
Chronic, Non-neuropathic Back Pain
Interventions
Mindfulness-Oriented Recovery Enhancement (MORE), Support Group
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
21 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 23, 2026, 11:08 PM EDT
Not listed Not applicable Interventional

MORE in the Management of Lumbosacral Radiculopathy Symptoms: A Randomized Controlled Trial

NCT04818606
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Mindfulness Oriented Recovery Enhancement
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Sep 23, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE

NCT07125027
View directory record Official record
Conditions
Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar, Chronic Pain (Back / Neck)
Interventions
Move-MORE
Behavioral
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 23, 2026, 11:08 PM EDT
Completed Not applicable Interventional

Mindfulness-Oriented Recovery Enhancement For Chronic Pain and Prescription Opioid Misuse in Primary Care

NCT02602535
View directory record Official record
Conditions
Chronic Pain, Opioid Use Disorders
Interventions
Mindfulness-Oriented Recovery Enhancement, Support Group
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 21, 2025 · Synced Sep 23, 2026, 11:08 PM EDT
Recruiting Phase 3 Interventional

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

NCT06387290
View directory record Official record
Conditions
Chronic Pain, Prescription Opioid Misuse, Substance-Related Disorders, Pain, Narcotic-Related Disorders, Chemically-Induced Disorders, Mental Disorders, Opioid-Related Disorders, Neurologic Manifestations
Interventions
Mindfulness Oriented Recovery Enhancement, Patient-Centered Chronic Pain Management Visits
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
La Jolla, California • New Brunswick, New Jersey • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 23, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

SMART Embedded Intervention for Military Postsurgical Engagement Readiness

NCT05050409
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
Brief mindfulness, Mindfulness-Oriented Recovery Enhancement (MORE), Standard care
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 23, 2026, 11:08 PM EDT