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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Minimally enhanced usual care Clear all
Completed Not applicable Interventional Results available

Trauma-informed Collaborative Care for Low-income African Americans With PTSD

NCT03591107
View directory record Official record
Conditions
PTSD
Interventions
PTSD Care Management (PCM), Minimally Enhanced Usual Care (MEU)
Other
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Sep 25, 2026, 7:42 PM EDT
Enrolling by invitation Phase 4 Interventional

Evaluating Worksite Sleep Health Coaching in Firefighters: The Sleep Assistance for Firefighters Study

NCT06684444
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Sleep Initiation and Maintenance Disorders, Sleep Deprivation, Sleep Disorders, Intrinsic
Interventions
firefighter Sleep Health Coaching Intervention (ffSHC), Control (Minimally Enhanced Usual Care)
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

Digital Cognitive-Behavioral Therapy for Insomnia in Spanish Speaking Latinas/os (Dormir Mejor Study)

NCT05353296
View directory record Official record
Conditions
Insomnia
Interventions
Digital cognitive behavioral therapy for insomnia (CBT-I) program, Minimally Enhanced Usual Care (mEUC), Somryst (culturally adapted)
Behavioral · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

SHARE: Sharing Healthcare Wishes in Primary Care

NCT04593472
View directory record Official record
Conditions
Cognitive Impairment
Interventions
Sharing Healthcare Wishes in Primary Care (SHARE), Minimally Enhanced Usual Care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
80 Years and older
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
9
States / cities
Baltimore, Maryland • Dundalk, Maryland • Mitchellville, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Dementia

NCT04338750
View directory record Official record
Conditions
Anxiety, Anxiety Generalized, Anxiety Disorders and Symptoms, Caregiver Burnout
Interventions
Telephone Acceptance and Commitment Therapy Intervention for Caregivers, minimally-Enhanced Usual Care
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

Toolkit for Optimal Recovery After Orthopedic Injury

NCT04973696
View directory record Official record
Conditions
Acute Orthopedic Injury
Interventions
Toolkit for Optimal Recovery after Orthopedic Injury, Minimally Enhanced Usual Care (MEUC)
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Sep 25, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Rise With Resilience

NCT07217275
View directory record Official record
Conditions
Athletic Injuries, Sport Injuries
Interventions
Community Resiliency Model (CRM), Control
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 26 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care

NCT01401101
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
PCM, MEU
Other
Lead sponsor
RAND
Other
Eligibility
18 Years to 65 Years
Enrollment
404 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
7
States / cities
Jersey City, New Jersey • Far Rockaway, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2016 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Treatment of Depression After Coronary Bypass Surgery

NCT00042198
View directory record Official record
Conditions
Depression, Coronary Disease
Interventions
Cognitive behavior therapy, Supportive Stress Management
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Sep 25, 2026, 7:42 PM EDT
Withdrawn Phase 2Phase 3 Interventional

GetHealthy-OA: A Program to Improve Pain and Function for Patients With Knee Osteoarthritis, Obesity, and Depression

NCT05482672
View directory record Official record
Conditions
Knee Osteoarthritis, Obese, Depression
Interventions
Fisetin, GetHealthy-OA mind-body program, Placebo oral capsule, Health education booklet
Drug · Behavioral
Lead sponsor
Cale Andrew Jacobs, PhD
Other
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 30, 2023 · Synced Sep 25, 2026, 7:42 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Early Intervention to Prevent Development of PTSD in Burn Survivors and Their Caregivers

NCT07656545
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Burns, Traumatic Injury, Acute Stress Disorder, Trauma and Stressor Related Disorders, Trauma and Stress Related Disorders, Stress Disorder, Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Relationship, Social
Interventions
Promotion of Emotional Disclosure for Burns (PoED-B), minimally Enhanced Usual Care control (mEUC)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Chronic Depression and PTSD in Stroke Patients Admitted to the Neuroscience Intensive Care Unit (NICU) and Their Family Caregivers

NCT02797509
View directory record Official record
Conditions
Neurological Disorder
Interventions
Psychosocial Skills-Based Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Sep 25, 2026, 7:42 PM EDT
Not yet recruiting Not applicable Interventional

A Structured Peer Support Intervention for Patients Undergoing Hematopoietic Stem Cell Transplantation

NCT07774104
View directory record Official record
Conditions
Hematopoietic Stem Cell Transplantation
Interventions
STEPP, Minimally Enhanced Usual Care Control
Behavioral · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Tampa, Florida • Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Behavioral Health Program for Short-Stay Nursing Facility Residents & Care Partners

NCT07220486
View directory record Official record
Conditions
Nursing Home Resident, Skilled Nursing Facility, Depression, Feasibility Studies, Caregiver
Interventions
Interventions for Stressful Transitions in Later Life
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 25, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest

NCT07143357
View directory record Official record
Conditions
Emotional Distress, Cardiac Arrest (CA), Anxiety, Depression, Caregivers, Survivorship, Resilience, Mindfulness
Interventions
Recovering Together after Cardiac Arrest 1, Recovering Together after Cardiac Arrest 2
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 25, 2026, 7:42 PM EDT
Active, not recruiting Phase 3 Interventional

Tele-Collaborative Outreach to Rural Patients With Chronic Pain

NCT06091202
View directory record Official record
Conditions
Chronic Pain
Interventions
CORPs Intervention, Minimally Enhanced Usual Care (MEUC)
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
608 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Minneapolis, Minnesota • Portland, Oregon • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Resilient Together for Dementia (RT-D)

NCT06619327
View directory record Official record
Conditions
Dementia
Interventions
Resilient Together for Dementia, MEUC
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

I-scan for Adenoma Detection

NCT02811419
View directory record Official record
Conditions
Colorectal Adenomatous Polyps
Interventions
i-scan, standard high-definition white light
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years to 75 Years
Enrollment
740 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Sep 25, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease

NCT06910969
View directory record Official record
Conditions
Bone Marrow Transplant Complications, Graft-versus-Host Disease
Interventions
HORIZONS Intervention, Minimally enhanced usual care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Miami, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Nurse-Led PTSD Treatment in Primary Care

NCT07430657
View directory record Official record
Conditions
Post Traumatic Stress Disorder PTSD
Interventions
NurseNET, Referral to PTSD Treatment
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Chicago, Illinois • Brookfield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community Health Workers and mHealth for Sickle Cell Disease Care

NCT03648710
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Peer Community Health Worker, Mobile Health
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
17 Years and older
Enrollment
405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
5
States / cities
Hartford, Connecticut • New Hyde Park, New York • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 25, 2026, 7:42 PM EDT
Recruiting Phase 2 Interventional

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

NCT06419439
View directory record Official record
Conditions
Chronic Low Back Pain, Depression
Interventions
Ketamine hydrochloride, Minimally Enhanced Usual Care, Brief narrative intervention
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 25, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With ADRD

NCT04780178
View directory record Official record
Conditions
Anxiety, Caregiver Burden
Interventions
Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults with Alzheimer's Disease and Related Dementias
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Sep 25, 2026, 7:42 PM EDT
Not listed Not applicable Interventional

Pain SMART: Shared Medical Appointments to Refocus Treatment

NCT03707886
View directory record Official record
Conditions
Chronic Pain
Interventions
Pain SMART, minimally enhanced usual care
Behavioral · Other
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Sep 25, 2026, 7:42 PM EDT