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Showing 1–24 of 121 matching trials from the live ClinicalTrials.gov search.
Conditions
Labor Induction
Interventions
Amniotomy, Foley Catheter, Misoprostol
Procedure · Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 4 Interventional Accepts healthy volunteers

Mifepristone and Misoprostol for Fetal Demise

NCT00177372
Conditions
Anembryonic Pregnancy, Gestation Abnormality, Intrauterine Fetal Demise Term
Interventions
mifepristone/misoprostol
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Pregnancy
Interventions
Buccal Misoprostol, Vaginal misoprostol
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Completed Early Phase 1 Interventional Accepts healthy volunteers

Buccal Versus Vaginal Misoprostol In Combination With Foley Bulb

NCT03976037
Conditions
Induction of Labor
Interventions
Misoprostol
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Clostridium Difficile
Interventions
Misoprostol 100Mcg Tab, Placebo
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
3
States / cities
St Louis, Missouri • Chapel Hill, North Carolina • Nashville, Tennessee
Conditions
Gastric Ulcer
Interventions
PN400 (VIMOVO), Diclofenac/Misoprostol
Drug
Lead sponsor
POZEN
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women

NCT00886834
Conditions
Contraception
Interventions
Misoprostol, Placebo
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Salt Lake City, Utah
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pitocin or Oral Misoprostol for PROM IOL

NCT04028765
Conditions
PROM
Interventions
Misoprostol, Oxytocin
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Cesarean Section, Misoprostol, Oxytocin, High Risk Pregnancy
Interventions
Oxytocin, Misoprostol
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Outpatient Cervical Ripening With Orally Administered Misoprostol in Diabetics

NCT00514618
Conditions
Diabetes, Gestational
Interventions
Misoprostol, Placebo
Drug · Dietary Supplement
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Long Beach, California
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Mail Order Mifepristone Study

NCT03913104
Conditions
Abortion Early, Pregnancy Related
Interventions
Mifepristone
Drug
Lead sponsor
Daniel Grossman, MD
Other
Eligibility
15 Years and older · Female only
Enrollment
536 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
11
States / cities
Oakland, California • Denver, Colorado • Wilmington, Delaware + 7 more
Completed No phase listed Observational

Outpatient Cervical Ripening

NCT04041687
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Misoprostol With Intrauterine Device Insertion

NCT00613366
Conditions
Contraception
Interventions
Misoprostol, Magnesium Oxide
Drug · Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Portland, Oregon
Conditions
Tibial Fractures, Pain
Interventions
600 mg Ibuprofen
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
13
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Cambridge, Massachusetts + 9 more
Conditions
Pregnancy, Labor
Interventions
Misoprostol, Pitocin
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Completed Not applicable Interventional Results available

Foley OR MisO for the Management of Induction

NCT01916681
Conditions
Delivery; Prolonged
Interventions
Cervical Foley & Misoprostol, Misoprostol Alone, Cervical Foley Alone, Cervical Foley & Pitocin
Device · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
491 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Phase 4 Interventional Results available

Misoprostol Dosing in BMI Greater Than 30

NCT05262738
Conditions
Pregnancy Related, Obesity, Labor Onset and Length Abnormalities
Interventions
50 Micrograms Vaginal Misoprostol (Intervention), 25 Micrograms Vaginal Misoprostol (Control)
Drug
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Conditions
Second Trimester Abortions
Interventions
Misoprostol administered vaginally, Misoprostol administered buccally, Misoprostol administered vaginally with Dilapan, Misoprostol administered buccally with Dilapan
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Silver Spring, Maryland
Conditions
Medical Abortion
Interventions
Mifepristone followed by misoprostol 24-48 hours later
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
11 Years to 55 Years · Female only
Enrollment
719 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
4
States / cities
Hartford, Connecticut • Atlanta, Georgia • Chicago, Illinois
Conditions
Legally Induced Abortion Without Mention of Complication
Interventions
Misoprostol, Mifepristone, Hygroscopic cervical dilators
Drug · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Jose, California
Conditions
Pregnancy
Interventions
30 mg letrozole followed by 800 mcg misoprostol
Drug
Lead sponsor
Gynuity Health Projects
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Pregnancy
Interventions
Foley catheter, Misoprostol
Device · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Abortion, Blood Loss
Interventions
Misoprostol, Folic acid
Drug · Other
Lead sponsor
Boston University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers

PROMMO Trial: Oral Misoprostol vs IV Oxytocin

NCT04478942
Conditions
Premature Rupture of Membrane, Induction of Labor Affected Fetus / Newborn
Interventions
Misoprostol Oral Product, Intravenous Oxytocin
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin