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Conditions: Obesity
Interventions: Behavioral Child Tx Contacts, Behavioral Parent-Tx Contacts, Dietary and Physical Activity Information; Behavioral · Other
Lead sponsor: University of Florida; Other
Eligibility: 8 Years to 12 Years
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Aging, Physical Activity, Vascular Health
Interventions: Aerobic Exercise Training; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 242 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Osteoarthritis
Interventions: Diet & Exercise, Attention Control; Behavioral
Lead sponsor: Wake Forest University; Other
Eligibility: 50 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Cherokee, North Carolina • Winston-Salem, North Carolina

Conditions: Uterine Fibroid
Interventions: LIFE program; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Metabolic Syndrome, Obesity
Interventions: Exercise Intervention; Behavioral
Lead sponsor: Plymouth State University; Other
Eligibility: 18 Years to 39 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 2
States / cities: Plymouth, New Hampshire

Conditions: Cachexia; Cancer, Weight Loss, Lung Cancer, Gastrointestinal Cancer
Interventions: Remune, EXCAP©®; Drug · Other
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Obesity, Primary
Interventions: g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors; Device
Lead sponsor: USGI Medical; Industry
Eligibility: 22 Years to 60 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obesity
Interventions: Stigma-Reduction Intervention, Behavioral Weight Loss (BWL); Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Diabetes Mellitus, Type 2, Obesity
Interventions: laparoscopic Roux-en-Y gastric bypass (RYGB) procedure, Lifestyle Intervention; Procedure · Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 25 Years to 65 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 2
States / cities: Seattle, Washington

Conditions: Obesity
Interventions: Daily Caloric Restriction (DCR), Intermittent Fasting (IMF); Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 60 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Endometrial Carcinoma, Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8, Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8, Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions: Aerobic Exercise, Biospecimen Collection, Dietary Intervention, Discussion, Goal Setting, Internet-Based Intervention, Medical Device Usage and Evaluation, Questionnaire Administration, Resistance Training, Smartphone Application-based Intervention, Supportive Care, Tailored Intervention; Other · Procedure · Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 40 Years to 69 Years · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Obesity, Weight Loss, Diet Modification, Aging, Weight Change, Body, Dietary Habits, Osteopenia, Osteoporosis, Bone Loss, Fractures, Bone
Interventions: Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement, 6-month NutraBio™ 100% Whey Protein Isolate Supplement, 18-month NutraBio™ 100% Whey Protein Isolate Supplement; Behavioral · Dietary Supplement
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 65 Years to 85 Years
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Obesity
Interventions: Building Habits Together Online Weight Loss 6-Week Usability Trial; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Obesity, Weight Loss, Diet Modification, Aging, Weight Change, Body, Dietary Habits
Interventions: Weight loss intervention months 0-6, Exercise intervention months 0-6, Carbohydrate supplement for months 0-6, Protein supplement for months 0-6, Protein supplement for follow-up months 7-18; Behavioral · Dietary Supplement
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 65 Years to 85 Years
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Obesity, Compensated Cirrhosis, Sarcopenia
Interventions: Continuous Energy Restriction (CER), Alternate Day Modified Fasting (ADMF), Group Health Education Sessions, Late Evening Snack, Physical activity, Self-monitoring, Remotely Supervised Exercise Sessions; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Motoric Cognitive Risk Syndrome
Interventions: Physical Activity (PA) Intervention, Healthy Aging Education (HE) Intervention; Other
Lead sponsor: Tufts University; Other
Eligibility: 60 Years to 89 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast Cancer, Obesity, Weight Changes
Interventions: behavioral dietary intervention, Exercise intervention; Behavioral
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 50 Years to 75 Years · Female only
Enrollment: 439 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Traumatic Brain Injury
Interventions: Telehealth-delivered Group Lifestyle Balance for people with TBI (tGLB-TBI), Brain Health Group (BHG); Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years to 80 Years
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obesity & Overweight
Interventions: Online Behavioral Obesity Treatment, Full Dietary Self-monitoring, Reduced-frequency Dietary Self-monitoring, Self-Monitoring of Dietary Lapses Only, Smartwatch-based Self-monitoring of Energy Intake, Self-monitoring of Body Weight Only; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 275 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obesity
Interventions: Behavioral Treatment, Placebo, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]; Behavioral · Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 70 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Non Hodgkin Lymphoma, Hodgkin Lymphoma
Interventions: LIFE-L Mediterranean Diet, LIFE-L Home-Based Exercise Program, Supportive Materials; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Obesity, Stroke
Interventions: Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 35 Years to 85 Years
Enrollment: 130 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Obesity, Sleep Apnea, Obstructive
Interventions: lifestyle intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 696 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Childhood Cancer Survivors
Interventions: Physical Activity; Behavioral
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 10 Years to 17 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Hershey, Pennsylvania

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Extension Family Lifestyle Intervention Project (E-FLIP for Kids)

Heterogeneity of Vascular Adaptations to Exercise With Aging in Women and Men

The Cherokee Study: Cherokee Health for Elderly Residents With Osteoarthritis of the Knee

Life Study: Lifestyle Intervention in Fibroid Elimination

Effects of Brisk Walking and Regular Intensity Exercise Interventions on Glycemic Control

Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia

A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm

Behavioral Weight Loss and Stigma Reduction

Calorie Reduction Or Surgery: Seeking Remission for Obesity And Diabetes

Intermittent Fasting Versus Daily Caloric Restriction for Weight Loss

Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C Trial

Utilizing Protein During Weight Loss to Impact Physical Function and Bone

Proof-of-Concept Study of an Integrated Mobile and Social Network Weight Loss Intervention

Utilizing Protein During Weight Loss to Impact Physical Function

OPTIMIzing muScle Preservation in paTients wIth Cirrhosis

ENGAGE for Brain Health

Effect of a Low-Calorie Diet and/or Exercise Program on Risk Factors for Developing Breast Cancer in Overweight or Obese Postmenopausal Women

Expanding Delivery of an Evidence-based Weight-loss Intervention to Enhance Access and Reach Underserved Groups After TBI

Microrandomized Trial to Optimize Use of Burden-reducing Self-monitoring Approaches in Behavioral Obesity Treatment

Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

Lifestyle Intervention of Food and Exercise for Lymphoma Survivors

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach

Physical Activity Post-Cancer for Adolescents and Young Adults