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Showing 1–24 of 75 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Mohs Surgery Clear all
Not yet recruiting Not applicable Interventional

A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer

NCT07032701
View directory record Official record
Conditions
Skin Carcinoma
Interventions
Best Practice, Educational Intervention, Electronic Health Record Review, Follow-Up Care, Medical Device Usage and Evaluation, Negative Pressure Wound Therapy, Photography, Questionnaire Administration
Other · Procedure
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
19 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 4, 2026, 11:57 AM EDT
Recruiting Phase 4 Interventional

Meloxicam in Mohs Micrographic Surgery

NCT07200544
View directory record Official record
Conditions
Postoperative Pain, Acute, Skin Cancer
Interventions
Meloxicam 7.5 mg, Meloxicam 15 mg, Acetaminophen 500mg
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 110 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 4, 2026, 11:57 AM EDT
Withdrawn Not applicable Interventional

Mohs and Immunofluorescence for Malignant Melanoma In Situ

NCT02306512
View directory record Official record
Conditions
Lentigo Maligna, Melanoma In Situ
Interventions
H&E, IHC MART-1, IF MART-1, IF cocktail
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 6, 2019 · Synced Sep 4, 2026, 11:57 AM EDT
Completed No phase listed Observational

Reflectance Confocal Microscopy of Wounds During Moh's Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins

NCT01872130
View directory record Official record
Conditions
Basal Cell Carcinoma, Squamous Cell Carcinoma
Interventions
Not listed
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
4
States / cities
Basking Ridge, New Jersey • Harrison, New York • Hauppauge, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Sep 4, 2026, 11:57 AM EDT
Active, not recruiting Not applicable Interventional

A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia

NCT05934851
View directory record Official record
Conditions
Vulvar Neoplasm, Dysplasia Vulvar
Interventions
Frozen-Section Directed Excision, Wide Local Excision
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 4, 2026, 11:57 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Optical Imaging for Preoperative Delineation of Nonmelanoma Skin Cancers

NCT02666833
View directory record Official record
Conditions
Carcinoma, Basal Cell, Carcinoma, Squamous Cell
Interventions
Polarization Enhanced Reflectance and Fluorescence System
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 14, 2016 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Not applicable Interventional

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

NCT06167096
View directory record Official record
Conditions
Skin Cancer, Skin Carcinoma
Interventions
Lavender essential oil, Water
Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 4, 2026, 11:57 AM EDT
Completed No phase listed Observational Results available

Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery

NCT00793169
View directory record Official record
Conditions
Basal Cell Carcinoma, Squamous Cell Carcinoma
Interventions
Blood Draw
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 5, 2021 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Early Phase 1 Interventional

Ethyl Chloride Spray to Reduce Pain From Local Anesthesia During Mohs Micrographic Surgery

NCT06920381
View directory record Official record
Conditions
Surgery
Interventions
Gebauer's Ethyl Chloride Topical Spray
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 4, 2026, 11:57 AM EDT
Completed No phase listed Observational

Interpolated Flap Study

NCT04164550
View directory record Official record
Conditions
Skin Cancer, Non-Melanoma, Skin Cancer Melanoma, Mohs Micrographic Surgery
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 4, 2026, 11:57 AM EDT
Enrolling by invitation No phase listed Observational

Clinical Registry Collecting Real World Evidence on Wound Care Treatments

NCT06328010
View directory record Official record
Conditions
Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed, Venous Leg Ulcer, Non-healing Wound, Trauma Injury, Injury and Wounds, Degloving Injuries, Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions
Various types of wound care treatments
Combination Product
Lead sponsor
Siddhey LLC
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
12
States / cities
Scottsdale, Arizona • Tempe, Arizona • Tucson, Arizona + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Not applicable Interventional Results available

Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities

NCT04545476
View directory record Official record
Conditions
Wound Heal
Interventions
Participants in this group will receive the experimental APIS Biomaterial on the Head., Participants in this group will receive the experimental APIS Biomaterial on the Lower Extremities., Standard Secondary Intention Healing on the Head, Standard Secondary Intention Healing on the Lower Extremities
Device · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 4, 2026, 11:57 AM EDT
Withdrawn No phase listed Observational

Mohs Micrographic Surgery and Reconstruction in the Optum Insurance Claims Database

NCT04117373
View directory record Official record
Conditions
Skin Cancer, Mohs Micrographic Surgery, Interpolated Flap Repair
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
1 Year to 99 Years
Timeline
2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Phase 3 Interventional Results available

Preoperative Acetaminophen and Carbohydrate Loading

NCT03131713
View directory record Official record
Conditions
Non-melanoma Skin Cancer
Interventions
Acetaminophen
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2019 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of the Subconscious on Mohs Micrographic Surgery

NCT00374062
View directory record Official record
Conditions
Basal Cell Carcinoma, Squamous Cell Carcinoma
Interventions
relaxation therapy 1, relaxation therapy 2, relaxation therapy 3
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
25 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 14, 2014 · Synced Sep 4, 2026, 11:57 AM EDT
Recruiting Not applicable Interventional

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

NCT07241585
View directory record Official record
Conditions
Nonmelanoma Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma
Interventions
Vitamin D (VitD), Placebo, Photodynamic therapy (PDT), Mohs surgery or electrodessication & curettage (ED&C) (standard of care)
Dietary Supplement · Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Split Face Study of the Duration of Local Anesthetics

NCT05767749
View directory record Official record
Conditions
Anesthetics, Local
Interventions
lidocaine + epinephrine 1:100,000, Ropivacaine 0.5% Injectable Solution, Bupivacaine 0.5% Injectable Solution
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Not applicable Interventional

Buddy Relationships in DermatoloGic Excisions for Skin Cancer

NCT04036344
View directory record Official record
Conditions
Skin Cancer Face, Quality of Life, Surgical Wound, Peer Mentorship
Interventions
Peer Mentorship Program
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 4, 2026, 11:57 AM EDT
Terminated No phase listed Observational

Pre-operative Consultation on Patient Anxiety and First-time Mohs Micrographic Surgery

NCT04612491
View directory record Official record
Conditions
Anxiety, Surgery
Interventions
Pre-operative Consultation
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 100 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Not applicable Interventional Results available

3D Printed Models in Mohs Micrographic Surgery

NCT03461965
View directory record Official record
Conditions
Mohs Micrographic Surgery
Interventions
3D printed model, Verbal Counselling
Behavioral
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years to 90 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Sep 4, 2026, 11:57 AM EDT
Completed Phase 2 Interventional Results available

Study of EB-001 in Facial Scar Reduction

NCT03346902
View directory record Official record
Conditions
Mohs Surgery
Interventions
EB-001, 0.9% Sodium Chloride Injection
Drug
Lead sponsor
Bonti, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 4, 2026, 11:57 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Tranexamic Acid in Nasal Mohs Reconstruction

NCT06057675
View directory record Official record
Conditions
Postoperative Bleeding, Skin Cancer Face
Interventions
Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine), Control (1% lidocaine with 1:100,000 epinephrine)
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 4, 2026, 11:57 AM EDT
Completed No phase listed Observational

Experience of Non-Melanoma Skin Cancer (NMSC) Mohs Surgery Project

NCT01452984
View directory record Official record
Conditions
Non-Melanoma Skin Cancer
Interventions
Not listed
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2015 · Synced Sep 4, 2026, 11:57 AM EDT
Not yet recruiting Phase 2 Interventional

Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds Healing

NCT07384767
View directory record Official record
Conditions
Mohs Micrographic Surgery, Excision Margin
Interventions
Timolol 0.5% Ophthalmic Solution, Hydrogel of placebo
Drug · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 4, 2026, 11:57 AM EDT