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ClinicalTrials.gov public records Last synced Sep 30, 2026, 1:14 PM EDT

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Showing 25–48 of 77 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Mohs surgery Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Lidocaine Jelly for Pain Control During Mohs Surgery

NCT03595449
View directory record Official record
Conditions
Pain, Satisfaction, Consumer
Interventions
Lidocaine jelly, Surgilube
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Not applicable Interventional

Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp

NCT06287866
View directory record Official record
Conditions
Scarring
Interventions
Pinch Graft
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Terminated Not applicable Interventional Results available

Secondary Intention Wound Healing Versus Micrografting in Patients Undergoing Mohs Surgery

NCT01442844
View directory record Official record
Conditions
Impaired Wound Healing
Interventions
Micrografting
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2014 · Synced Sep 30, 2026, 1:14 PM EDT
Terminated Early Phase 1 Interventional

Use of Tranexamic Acid in Reduction of Post-Op Complications in Mohs Micrographic Surgery

NCT04630886
View directory record Official record
Conditions
Skin Neoplasms
Interventions
Tranexamic acid injection, Lidocaine Epinephrine
Drug
Lead sponsor
Riley McLean
Other
Eligibility
18 Years to 99 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 30, 2026, 1:14 PM EDT
Not yet recruiting Phase 2 Interventional

The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial

NCT07583862
View directory record Official record
Conditions
Surgical Wounds, Mohs Surgery
Interventions
Topical Timolol, Normal Saline
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Not yet recruiting Phase 4 Interventional

Impact of Dysport on PMFF Donor Scar

NCT07720726
View directory record Official record
Conditions
Skin Cancer Excision Site, Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma
Interventions
Abobotulinumtoxin-A, Control- Saline injection
Drug · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Bupivacaine for Post-operative Pain in Mohs

NCT04362566
View directory record Official record
Conditions
Pain, Postoperative, Narcotic Use
Interventions
Bupivacaine, Placebo Saline
Drug · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Sep 30, 2026, 1:14 PM EDT
Not yet recruiting Phase 2 Interventional

Efficacy and Safety of Topical Timolol in Secondary Intention Surgical Wounds Healing

NCT07384767
View directory record Official record
Conditions
Mohs Micrographic Surgery, Excision Margin
Interventions
Timolol 0.5% Ophthalmic Solution, Hydrogel of placebo
Drug · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Tranexamic Acid in Nasal Mohs Reconstruction

NCT06057675
View directory record Official record
Conditions
Postoperative Bleeding, Skin Cancer Face
Interventions
Treatment (tranexamic acid and 1% lidocaine with 1:100,000 epinephrine), Control (1% lidocaine with 1:100,000 epinephrine)
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Completed No phase listed Observational

Experience of Non-Melanoma Skin Cancer (NMSC) Mohs Surgery Project

NCT01452984
View directory record Official record
Conditions
Non-Melanoma Skin Cancer
Interventions
Not listed
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 19, 2015 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Phase 2 Interventional Results available

Study of EB-001 in Facial Scar Reduction

NCT03346902
View directory record Official record
Conditions
Mohs Surgery
Interventions
EB-001, 0.9% Sodium Chloride Injection
Drug
Lead sponsor
Bonti, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Sep 30, 2026, 1:14 PM EDT
Not yet recruiting Phase 4 Interventional

Suzetrigine Versus Standard Analgesia After Skin Cancer Surgery

NCT07843134
View directory record Official record
Conditions
Postoperative Pain, Acute Pain, Skin Cancer, Cutaneous Malignancy, Mohs Surgery
Interventions
Suzetrigine, Acetaminophen Plus Ibuprofen
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
3
States / cities
Maple Grove, Minnesota • Minneapolis, Minnesota • Wyoming, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Completed No phase listed Observational

Reflectance Confocal Microscopy of Wounds During Moh's Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins

NCT01872130
View directory record Official record
Conditions
Basal Cell Carcinoma, Squamous Cell Carcinoma
Interventions
Not listed
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
4
States / cities
Basking Ridge, New Jersey • Harrison, New York • Hauppauge, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2020 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Early Phase 1 Interventional Results available

Vismodegib in Treating Patients With Basal Cell Carcinoma (BCC)

NCT01631331
View directory record Official record
Conditions
Basal Cell Carcinoma of the Skin, Recurrent Skin Cancer
Interventions
vismodegib, Mohs surgery
Drug · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Sep 30, 2026, 1:14 PM EDT
Not listed Not applicable Interventional

Use of the Epidermal Micrografts for Wound Healing After Mohs or Excisional Surgery for Skin Cancer

NCT01536444
View directory record Official record
Conditions
Neoplasm of Skin
Interventions
Momelan Technologies Epidermal Graft Harvesting System
Device
Lead sponsor
Momelan Technologies
Industry
Eligibility
35 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Naperville, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 22, 2012 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Not applicable Interventional

Assessing Patient Anxiety During Mohs Micrographic Surgery

NCT03756792
View directory record Official record
Conditions
Anxiety
Interventions
Normal Education Material, Vignette
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery

NCT00578214
View directory record Official record
Conditions
Basal Cell Carcinoma, Squamous Cell Carcinoma, Skin Cancer, Anxiety
Interventions
Randomized Midazolam, Placebo, Local Anesthesia, Prospective Midazolam
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 9, 2012 · Synced Sep 30, 2026, 1:14 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

NCT03370406
View directory record Official record
Conditions
Carcinoma, Squamous Cell
Interventions
5-fluorouracil, Calcipotriene
Drug
Lead sponsor
Melissa Pugliano-Mauro
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Not applicable Interventional Results available

Investigation of Mohs Surgical Margins Using Two Photon Microscopy

NCT05814900
View directory record Official record
Conditions
Basal Cell Carcinoma
Interventions
Two photon microscopy imaging
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Victor, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Enrolling by invitation Phase 4 Interventional

Local Anesthetic Clinical Trial

NCT07601750
View directory record Official record
Conditions
Mohs Micrographic Surgery, Anesthesia, Local
Interventions
Lidocaine, Bupivacaine Hydrochloride, Mepivacaine Hydrochloride, Chlorprocaine
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Completed No phase listed Observational Results available

Comparison of eBX and Mohs Surgery for Treatment of Early-stage Non-melanoma Skin Cancer a Matched Pair Cohort Study.

NCT03024866
View directory record Official record
Conditions
Nonmelanoma Skin Cancer
Interventions
Electronic Brachytherapy
Procedure
Lead sponsor
Xoft, Inc.
Industry
Eligibility
41 Years and older
Enrollment
369 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
4
States / cities
Los Gatos, California • San Diego, California • Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Sep 30, 2026, 1:14 PM EDT
Recruiting Phase 4 Interventional

Meloxicam in Mohs Micrographic Surgery

NCT07200544
View directory record Official record
Conditions
Postoperative Pain, Acute, Skin Cancer
Interventions
Meloxicam 7.5 mg, Meloxicam 15 mg, Acetaminophen 500mg
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 110 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 30, 2026, 1:14 PM EDT
Active, not recruiting Not applicable Interventional

A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia

NCT05934851
View directory record Official record
Conditions
Vulvar Neoplasm, Dysplasia Vulvar
Interventions
Frozen-Section Directed Excision, Wide Local Excision
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 30, 2026, 1:14 PM EDT
Completed Early Phase 1 Interventional

Non-invasive Fluorescent Imaging System for Imaging Mohs Tumor

NCT03430934
View directory record Official record
Conditions
Skin Cancer
Interventions
NAVI mapping with Indocyanine green
Combination Product
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Sep 30, 2026, 1:14 PM EDT