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Showing 25–45 of 21 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Monopolar Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment

NCT07187297
View directory record Official record
Conditions
Wrinkle, Lax Skin, Lines Skin
Interventions
Thermage FLX
Device
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
30 Years to 60 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
6
States / cities
Sacramento, California • San Diego, California • Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Not applicable Interventional Results available

Pivotal Study of the NanoKnife System for the Ablation of Prostate Tissue

NCT04972097
View directory record Official record
Conditions
Prostate Cancer
Interventions
Irreversible Electroporation
Device
Lead sponsor
Angiodynamics, Inc.
Industry
Eligibility
50 Years and older · Male only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
17
States / cities
Orange, California • Aurora, Colorado • Gainesville, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Not applicable Interventional

Characterizing Stray Energy Injuries During Robotic Surgery

NCT03477201
View directory record Official record
Conditions
Port-site Injury Caused by Stray Energy Transfer
Interventions
Laparoscopic robotic DaVinci assisted inguinal hernia repair, Standard laparoscopic inguinal hernia repair
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Male only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Not applicable Interventional Results available

PlasmaKinetic (PK) Button Vaporization Electrode for Treatment of Bladder Tumors

NCT01567462
View directory record Official record
Conditions
Bladder Cancer
Interventions
Monopolar electrocautery loop in Transurethral resection of bladder tumors, PK Button Vaporization Electrode in transurethral resection of bladder tumors
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 12, 2026, 4:57 AM EDT
Recruiting Not applicable Interventional

Electrophysiology-based DBS Programming for PD

NCT07348705
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
Clinician-based DBS programming, Maximum Beta power-based DBS programming, Broad-band electrophysiology-based DBS programming
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 12, 2026, 4:57 AM EDT
Terminated Not applicable Interventional Results available

Efficacy of Cooled and Monopolar Radiofrequency Ablation of the Geniculate Nerves for the Treatment of Chronic Osteoarthritic Knee Pain

NCT02260869
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Genicular nerve radiofrequency ablation, Pain Management Radiofrequency Kit
Procedure · Device
Lead sponsor
Millennium Pain Center
Other
Eligibility
18 Years to 100 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
3
States / cities
Bloomington, Illinois • Decatur, Illinois • Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Laparoscopic Cholecystectomy And Capacitive Coupling - Coag Versus Blend Mode Causing Thermal Injury at Port Site Skin

NCT01664806
View directory record Official record
Conditions
Intraoperative Complications, Thermal Injury, Electrocoagulation
Interventions
Covidien Triad monopolar generator
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 24, 2013 · Synced Sep 12, 2026, 4:57 AM EDT
Completed No phase listed Observational

Histological Characterization of Vaginal Cuff Tissue Using Different Energy Sources During Robotic Hysterectomy

NCT01846858
View directory record Official record
Conditions
Extent of Thermal Injury Using Different Energy Sources at the Time of Robotic Hysterectomy Procedure
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Sep 12, 2026, 4:57 AM EDT
Withdrawn No phase listed Observational

Pancreatic Cyst Ablation With a Monopolar Radiofrequency Ablation Probe

NCT04253249
View directory record Official record
Conditions
Treatment Related Cancer
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 12, 2026, 4:57 AM EDT
Active, not recruiting Not applicable Interventional

Monopolar Current Cutting Knife vs Bipolar RFA Knife

NCT04919824
View directory record Official record
Conditions
Gastrointestinal Neoplasms
Interventions
Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Not applicable Interventional Results available

CUSTOM-DBS: Current Steering to Optimize Deep Brain Stimulation

NCT01896115
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Vercise DBS settings
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Valencia, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Sep 12, 2026, 4:57 AM EDT
Terminated Phase 4 Interventional Results available

Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain

NCT05409443
View directory record Official record
Conditions
Sacroiliac Joint Complex, Low Back Pain
Interventions
Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA), Conventional Sacroiliac Joint Radiofrequency Ablation (C-SIJRFA)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Farmington, Utah • Salt Lake City, Utah • South Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 12, 2026, 4:57 AM EDT
Terminated Not applicable Interventional

DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET)

NCT05096572
View directory record Official record
Conditions
Essential Tremor
Interventions
VIM Stimulation, PSA Stimulation, VIM+PSA Stimulation
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 12, 2026, 4:57 AM EDT
Terminated Not applicable Interventional Results available

Therapy Cool Path Ablate VT

NCT00925522
View directory record Official record
Conditions
Ischemic Ventricular Tachycardia
Interventions
Therapy Cool Path Duo Cardiac Ablation System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
5
States / cities
Birmingham, Alabama • Maywood, Illinois • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 12, 2026, 4:57 AM EDT
Withdrawn Not applicable Interventional

Monopolar and Bipolar in Esophageal ESD

NCT05736705
View directory record Official record
Conditions
Esophageal Neoplasm, Esophageal Polyp, Endoscopic Submucosal Dissection, Bipolar Electocautery
Interventions
Endoscopic Submucosal Dissection, Bipolar electrocautery knife
Procedure · Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 12, 2026, 4:57 AM EDT
Completed No phase listed Observational

Automated Parkinson's Disease (PD) Motor Symptom Assessment for Deep Brain Stimulation (DBS) Programming

NCT01429220
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
21 Years to 90 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2014 · Synced Sep 12, 2026, 4:57 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Tradeoff Between Spatial and Temporal Resolution

NCT03867058
View directory record Official record
Conditions
Deafness
Interventions
Electrode selection/electrode configuration
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
15 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Thermal Outcome and Safety of Nuera Tight RF System

NCT05957029
View directory record Official record
Conditions
To Verify Tissue Heating and Temperature Stability and Safety Throughout RF Treatment Duration Applied on the Face
Interventions
NuEra Tight RF system
Device
Lead sponsor
Lumenis Be Ltd.
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Detroit, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Renuvion APR System When Used as an Adjunct Procedure In Gynecomastia Surgery

NCT05093049
View directory record Official record
Conditions
Gynecomastia
Interventions
Renuvion APR System, Gynecomastia Correction Surgery
Device · Procedure
Lead sponsor
Apyx Medical
Industry
Eligibility
18 Years to 75 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Sep 12, 2026, 4:57 AM EDT
Active, not recruiting Not applicable Interventional

Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)

NCT04996173
View directory record Official record
Conditions
Pulmonary Disease
Interventions
Spray cryotherapy, Ballon Dilation, Radial Incision
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Jackson, Mississippi • Nashville, Tennessee • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 12, 2026, 4:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cochlear Promontory Stimulation for Treatment of Tinnitus

NCT03759834
View directory record Official record
Conditions
Tinnitus
Interventions
Cochlear promontory stimulation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Sep 12, 2026, 4:57 AM EDT