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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Mood Induction Clear all
Completed Phase 4 Interventional

Comparing the Effects of Four Types of Electroconvulsive Therapy on Mood and Thinking in People With Depression

NCT00487500
View directory record Official record
Conditions
Depression
Interventions
Electroconvulsive Therapy (ECT)
Device
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2014 · Synced Sep 2, 2026, 4:15 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Alcohol and Mood on Attention

NCT04276779
View directory record Official record
Conditions
Suicidal Ideas
Interventions
Alcohol administration, Placebo administration, Positive mood induction, Negative mood induction
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Phase 2 Interventional Results available

Estrogen Receptor Beta and Mood

NCT03689543
View directory record Official record
Conditions
Perimenopause-Related Depression
Interventions
Estradiol, ER Beta Agonist, Placebo, Provera
Drug · Other
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
45 Years to 65 Years · Female only
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 2, 2026, 4:15 PM EDT
Recruiting Not applicable Interventional

Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents

NCT07626944
View directory record Official record
Conditions
BPSD, Caregiver Distress, Well-being, Mood
Interventions
Personalized Music Listening (PML), Binaural Beat Music (BBM), Spatialized Music (SM)
Other
Lead sponsor
Maharishi International University
Other
Eligibility
55 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Denver, Colorado • Lakewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Results available

Check It! 2.0: Positive Psychology Intervention for Adolescents With Type 1 Diabetes

NCT02984709
View directory record Official record
Conditions
Type1diabetes
Interventions
Positive Psychology Intervention, Education
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
13 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Sep 2, 2026, 4:15 PM EDT
Not yet recruiting Phase 4 Interventional

Neuromodulation of Mood Switch Circuitry in Bipolar Disorder

NCT07680153
View directory record Official record
Conditions
Bipolar Disorder (BD), Bipolar 1 Depression, rTMS, fMRI
Interventions
MagVenture MagPro TMS system, Sham Stimulation
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study Comparing Two Versions of Group Cognitive-behavioral Indicated Prevention Programs

NCT04111887
View directory record Official record
Conditions
Depressive Symptoms
Interventions
Group-based therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
18 Years to 28 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Impact of Hot Flashes on Sleep and Mood Disturbance

NCT01116401
View directory record Official record
Conditions
Menopause, Depression, Hot Flashes
Interventions
leuprolide
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Mobile-Web Emotion Self-management Tool

NCT02346591
View directory record Official record
Conditions
Stress, Depression
Interventions
Jauntly, Online stress management information
Behavioral
Lead sponsor
Oregon Center for Applied Science, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Phase 3 Interventional Results available

Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

NCT00068445
View directory record Official record
Conditions
Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
lamotrigine, Placebo
Drug · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2013
U.S. locations
23
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Atlanta, Georgia + 20 more
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Sep 2, 2026, 4:15 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Enhancing Psychotherapy for Mood Disorders With Whole Body Hyperthermia

NCT02021149
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
High intensity whole-body infrared heating, Psychotherapy, Questionnaires, Low intensity whole-body infrared heating
Device · Behavioral · Other
Lead sponsor
Charles (Chuck) Raison
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 26, 2015 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Phase 3 Interventional Results available

Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine

NCT03831854
View directory record Official record
Conditions
Reducing Psychological Side Effects of Ketamine
Interventions
Lamotrigine 300 MG, Placebo, Ketamine
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Sep 2, 2026, 4:15 PM EDT
Recruiting No phase listed Observational

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

NCT06683092
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
RETRIAL-Mental Health, RETRIAL-Liver, RETRIAL-Neuro
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
18
States / cities
Birmingham, Alabama • Aurora, Colorado • Denver, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 2, 2026, 4:15 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Smoked Nicotine Induced Changes in Hormone Function, Mood States and Behaviors

NCT01636323
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine
Other
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 14, 2013 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Pilot Study of Entacapone for Methamphetamine Abuse

NCT02058966
View directory record Official record
Conditions
Methamphetamine Dependence
Interventions
Entacapone, Methamphetamine, Placebo
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Results available

A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)

NCT03687970
View directory record Official record
Conditions
Chemotherapy-induced Peripheral Neuropathy
Interventions
Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory, Diode Laser fiber type Selective Stimulator, Quantitative sensory testing, Conditioned pain modulation efficiency, Spontaneous pain at baseline on 0-10 Numerical Rating Scale (NRS)
Other · Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Understanding Experimentally Induced Hot Flushes

NCT00455689
View directory record Official record
Conditions
Hot Flashes
Interventions
Leuprolide acetate
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Relora Supplement on Anxiety, Cognitive Performance & Mood Tested After Induced Stress

NCT02734251
View directory record Official record
Conditions
Mood (Psychological Function)
Interventions
Relora, Placebo
Dietary Supplement
Lead sponsor
InterHealth Nutraceuticals, Inc.
Industry
Eligibility
21 Years to 59 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2016
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated May 23, 2016 · Synced Sep 2, 2026, 4:15 PM EDT
Recruiting Not applicable Interventional

Mind After Midnight

NCT07438912
View directory record Official record
Conditions
Suicidal Ideation, Circadian Rhythm Disorders, Sleep Deprivation, Sleep Wake Disorders
Interventions
Sleep Pressure Manipulation
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 2, 2026, 4:15 PM EDT
Terminated Phase 4 Interventional

Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes

NCT00283309
View directory record Official record
Conditions
Mood, Memory Deficit
Interventions
Memantine, Riluzole
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 22, 2013 · Synced Sep 2, 2026, 4:15 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuroimaging of St. John's Wort-Induced Changes of Serotonin Metabolism in Normal Subjects

NCT00001919
View directory record Official record
Conditions
Healthy, Mood Disorder
Interventions
Hypericum (LI-160)
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 2, 2026, 4:15 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Men, Mood, and Attention Study: Examination of Alcohol, State Anger, and Emotion Regulation Sexual Aggression

NCT04192448
View directory record Official record
Conditions
Alcohol Intoxication, Anger
Interventions
Alcohol Administration, Mood Induction
Other
Lead sponsor
Elizabeth C Neilson
Other
Eligibility
21 Years to 35 Years · Male only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Morehead, Kentucky
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multisite Virtual Reality Intervention for Speech Anxiety

NCT06593847
View directory record Official record
Conditions
Public Speaking, Speech Anxiety
Interventions
Single-session VR exposure intervention
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 70 Years
Enrollment
1,542 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
6
States / cities
Tucson, Arizona • Carbondale, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 2, 2026, 4:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies for Coping With Negative Thoughts

NCT05566691
View directory record Official record
Conditions
Depressive Symptoms, Anxiety, Negative Thinking
Interventions
Positive thinking, Positive thinking + Mood induction, Thought reevaluation, Thought reevaluation + Mood induction
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2023 · Synced Sep 2, 2026, 4:15 PM EDT