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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:34 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 266 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Mood Management Clear all

Conditions: Anxiety, Substance Use Disorders
Interventions: IMPROVE, PHET; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Alcoholism, Smoking
Interventions: nicotine replacement patch, mood management; Drug · Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2003
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Depressive Disorder, Major, Suicidal Ideation
Interventions: Ketamine; Drug
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Musculoskeletal Strain, Musculoskeletal Sprain, Injury of Musculoskeletal System
Interventions: Computer based pain management; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Baltimore, Maryland • Nashville, Tennessee

Conditions: Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression, Opioid Use Disorder
Interventions: FORT-A, VA Treatment as Usual; Behavioral · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 72 Years
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Problematic Phone Use Behavior, Depression, Anxiety
Interventions: Mindwire; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 13 Years to 19 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Pain, Mood, Patient Satisfaction, Scheduled Cesarean Sections
Interventions: Lavender-sandalwood aromatherapy tabs; Other
Lead sponsor: Memorial Hermann Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Drug Discontinuation, Substance Use Disorders, Eating Behavior Changes, Tirzepatide
Interventions: Discontinuation and Reinitiation of Tirzepatide; Other
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Mood Disorders
Interventions: Mindfulness-Based Intervention (MBI), Health and Wellness Intervention (HWI); Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 11 Years to 14 Years
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Depression, Social Stress, Anxiety, Quality of Life, Disaster
Interventions: Technical Assistance, Community Engagement and Planning, Community Resources (CR), Community Resources + eBT; Other
Lead sponsor: Louisiana State University Health Sciences Center in New Orleans; Other
Eligibility: 18 Years and older
Enrollment: 258 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Advanced Lung Carcinoma, Extensive Stage Lung Small Cell Carcinoma, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8, Unresectable Lung Carcinoma, Unresectable Lung Non-Small Cell Carcinoma
Interventions: Physical Therapy, Quality-of-Life Assessment, Questionnaire Administration, Relaxation Therapy; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 60 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Mood Change, Depressive Symptoms, Anxiety Generalized
Interventions: Integrative-Mind-Body Skills Group; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Chronic Pain
Interventions: Cognitive Behavioral Therapy (CBT), Exercise Counseling and tele-EnhanceFitness, Care Coordination, Standard Clinical Practice Regimen; Behavioral · Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Rheumatoid Arthritis, Obesity, Pain
Interventions: Enhanced Lifestyle Weight Management; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Mood
Interventions: Activities., Wait list; Behavioral · Other
Lead sponsor: i4Health; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Cancer Pain, Opioid Use, Cognitive Behavior Therapy
Interventions: Cognitive Behavioral Therapy for pain; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Torticollis, Dystonia
Interventions: CBT; Behavioral
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years to 75 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Acute Coronary Syndrome, Tobacco Use
Interventions: Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS), Smoking cessation plus Health and Wellness; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Bipolar Disorder
Interventions: Experimental Diet, Comparator Diet; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Mood Disorder, Disruptive Behavior Disorders
Interventions: Oxytocin, Placebo; Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 10 Years to 18 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Aging, Dementia, Cognitive Decline
Interventions: utmbHealthyBrain Smartphone App; Behavioral
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 50 Years to 100 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Major Depressive Disorder, Recurrent, in Remission, Depressive Symptoms
Interventions: Usual Depression Care, Mindful Mood Balance; Behavioral
Lead sponsor: University of Toronto; Other
Eligibility: 18 Years and older
Enrollment: 460 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Cigarette Addiction, Tobacco Use Disorder
Interventions: Biospecimen Collection, Questionnaire Administration, Cigarette Purchase Task, Cross-Price Elasticity Task, Daily Diary Surveys, Progressive Ratio Task; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Health Behavior, Quality of Life, Aging
Interventions: Not listed
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 110 Years
Enrollment: 10,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Orlando, Florida

Search by objective public record fields.

Intervention for Managing Physical Reactions to Overwhelming Emotions

Behavioral Counseling for Alcohol Dependent Smokers (Nicotine Patch)

Ketamine for Mood Disorders With Suicidal Ideation

Pain Management Following Musculoskeletal Injury

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

The Mindful Smartphone Use Study

Lavender Sandalwood Aromatherapy Study

Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation

Brain, Emotions, and Mind-Wandering

Community Resilience Learning Collaborative and Research Network

Resiliency Among Older Adults Receiving Lung Cancer Treatment

Mind-Body Skills Group for Graduate Students

Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain

Rheumatoid Arthritis Coping Enhancement

Mood Management Effects of Brief Unsupported Internet Interventions II

Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain

OnabotulinumtoxinA in the Management of Psychogenic Dystonia

Integrated Smoking Cessation and Mood Management for ACS Patients

Dietary Intervention for Bipolar Disorder

Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders

Feasibility of A Smartphone Application Intervention in Community Settings: A Pretest-Posttest Pilot Study

Reducing Residual Depressive Symptoms With Web-based Mindful Mood Balance

Impact of Novel vs. Usual Brand Menthol Cigarettes on Abuse Liability

The Lake Nona Life Project