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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Morning Bright Light Therapy Clear all
Completed Not applicable Interventional

Out-patient Wake Therapy, Light Therapy and Sleep Phase Advance for Depression

NCT02750631
View directory record Official record
Conditions
Unipolar Depression
Interventions
Triple Therapy
Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2017 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional

Bright Light Therapy for Sleep Disturbance in People With Multiple Sclerosis

NCT04054050
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Light therapy
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Noradrenergic Dysregulation, Sleep and Cognition in Older Adults With Insomnia

NCT06694441
View directory record Official record
Conditions
Insomnia
Interventions
Light Exposure, Placebo
Other
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

A Wearable Morning Light Treatment for Postpartum Depression

NCT04845347
View directory record Official record
Conditions
Post Partum Depression
Interventions
Bright Light Therapy, Dim Light Therapy
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

Fibromyalgia Sleep A to ZZZ Study

NCT06567886
View directory record Official record
Conditions
Fibromyalgia
Interventions
Light Therapy, Sleep Stabilization
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Morning Bright Light to Improve Sleep Quality in Veterans

NCT03578003
View directory record Official record
Conditions
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
Interventions
Morning Bright Light Therapy
Other
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Portand, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Bright Light Treatment At Home To Manage Chronic Pain In U.S. Veterans

NCT02373189
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Bright light
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Sep 2, 2026, 6:49 AM EDT
Terminated Not applicable Interventional

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

NCT06626334
View directory record Official record
Conditions
Rib Fractures, Pain, Acute
Interventions
Bright Blue Light, Bright Full-Spectrum (White) Light, Usual Ambient Light
Device
Lead sponsor
Rebecca E Kotcher, MD
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Potentials of Biodynamic Lighting for Home Office Workers

NCT05481424
View directory record Official record
Conditions
Cognitive Performance, Sleep, Alertness
Interventions
Biodynamic, Active Placebo
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional

Alternative Treatments for Premenstrual Dysphoric Disorder

NCT01799733
View directory record Official record
Conditions
Premenstrual Dysphoric Disorder
Interventions
LWT+AM BWL, EWT+PM BWL
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional

A Pilot Test of Mood and Circadian Rhythm Mechanisms Driving Binge Eating

NCT03680989
View directory record Official record
Conditions
Eating Disorder, Binge Eating, Circadian Dysregulation
Interventions
Bright Light Exposure, Natural Light Exposure
Device
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Morning Light Treatment at Home to Reduce PTSD Symptoms

NCT03513848
View directory record Official record
Conditions
PTSD
Interventions
Retimer, Retimer placebo
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

NCT05579392
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
Bright Light Therapy, Placebo Retimer Device
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

Pilot Trial of Phototherapy for Acute Depression in Hospitalized Cystic Fibrosis Patients

NCT01822197
View directory record Official record
Conditions
Depression, Cystic Fibrosis
Interventions
Phototherapy
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2016 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function

NCT05691439
View directory record Official record
Conditions
Depression in Adolescence
Interventions
Sleep extension and advance, Regular sleep duration and timing
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
14 Years to 18 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Morning Light Treatment to Improve Glucose Metabolism

NCT03188263
View directory record Official record
Conditions
PreDiabetes, Circadian Dysregulation
Interventions
Bright Light, Dim Light
Other
Lead sponsor
Northwestern University
Other
Eligibility
35 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Results available

The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS

NCT05299723
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Acute Coronary Syndrome
Interventions
BLT Intervention, BLB Intervention, Sleep Hygiene Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens

NCT04792697
View directory record Official record
Conditions
Delayed Sleep Phase Syndrome
Interventions
Increase morning bright light, Decrease evening blue light, Sleep Scheduling, Monitor sleep, mood, and substance use
Other · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 15 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Terminated Not applicable Interventional Results available

Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer

NCT06164691
View directory record Official record
Conditions
Pancreatic Neoplasms, Rectal Neoplasms
Interventions
Blue light, Amber light, Ambient White Light
Device · Other
Lead sponsor
Matthew Neal MD
Other
Eligibility
19 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Delayed Sleep Timing in Teens Study

NCT03806296
View directory record Official record
Conditions
Delayed Sleep Phase
Interventions
Increase morning bright light, Decrease evening blue light, Sleep scheduling, Monitor sleep, mood, and substance use
Other · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 19 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

Light Therapy to Improve Sleep in TBI: Sleep-active Biomarkers and Glymphatic Function

NCT07601841
View directory record Official record
Conditions
Sleep, Phototherapy, Glymphatic System, Mitochondrial Dynamics, Brain Injuries, Traumatic, Inflammation
Interventions
Morning Bright Light Therapy, Negative Ion Generator Therapy
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nighttime Synchrony of Your Nutrition and Circadian Health

NCT07329283
View directory record Official record
Conditions
Sleep, Metabolism Changes, Circadian Rhythm, Lifestyle Factors, Sleep Hygiene, Sleep Hygiene, Inadequate, Sleep Deprivation, Insufficient Sleep, Circadian Misalignment, Circadian Dysregulation, Light Exposure
Interventions
Central Clock Misalignment, Peripheral Misalignment
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 2, 2026, 6:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors

NCT03304587
View directory record Official record
Conditions
Breast Cancer
Interventions
Polysomnography (PSG), Rectal thermistor 400 Series, Bright blue-green light, Dim red light, Digital foot candle datalogging light meter, Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue, Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance, Patient-Reported Outcomes Measurement Information System (PROMIS)-Depression, Patient-Reported Outcomes Measurement Information System (PROMIS)-Physical Function, Pittsburgh Sleep Quality Index (PSQI), Center for Epidemiological Studies - Depression, Montreal Cognitive Assessment (MoCA), European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ-C30), Daily Log
Diagnostic Test · Other
Lead sponsor
Michigan State University
Other
Eligibility
21 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced Sep 2, 2026, 6:49 AM EDT
Recruiting Not applicable Interventional

Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

NCT05519878
View directory record Official record
Conditions
Bladder Carcinoma, Genitourinary System Neoplasm, Kidney Carcinoma, Prostate Carcinoma
Interventions
Best Practice, Bright White Light Therapy, Occupational Therapy, Questionnaire Administration
Other · Device · Behavioral
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 2, 2026, 6:49 AM EDT