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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Morning bright light therapy Clear all
Completed Phase 1 Interventional

Bright Light on Fatigue in Women Being Treated for Breast Cancer

NCT02658708
View directory record Official record
Conditions
Breast Neoplasms, Breast Cancer, Cancer of Breast, Cancer of the Breast
Interventions
Bright blue-green light using light visor cap, Dim red light using light visor cap, European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance, Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue, Digital foot candle datalogging light meter (Extech Instrument, Model SDL400), Polysomnography (Easy Ambulatory 2 Cadwell, Kennewick, WA), Horne-Ostberg Morningness-Eveningness Questionnaire, Daily Fatigue and Sleep Log
Other · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional

Bright Light Therapy for Sleep Disturbance in People With Multiple Sclerosis

NCT04054050
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Light therapy
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Light Heart Study: Daily Light Box Use for Depressive Symptoms in Patients With Stage B Heart Failure

NCT02691000
View directory record Official record
Conditions
Depression, Stage B Heart Failure
Interventions
LiteBook
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
60 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy and Light Therapy

NCT05337943
View directory record Official record
Conditions
Pulmonary Hypertension, Insomnia, Fatigue
Interventions
CBT-I, Bright Light Therapy
Behavioral · Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Combined Blue and Red Home-Based Light Therapy on Sleep in Adults With Self-Reported Sleep Difficulties

NCT07465250
View directory record Official record
Conditions
Sleep
Interventions
LED portable light therapy bulb
Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional

Alternative Treatments for Premenstrual Dysphoric Disorder

NCT01799733
View directory record Official record
Conditions
Premenstrual Dysphoric Disorder
Interventions
LWT+AM BWL, EWT+PM BWL
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS

NCT05299723
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Acute Coronary Syndrome
Interventions
BLT Intervention, BLB Intervention, Sleep Hygiene Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Sep 3, 2026, 11:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Morning Bright Light to Improve Sleep Quality in Veterans

NCT03578003
View directory record Official record
Conditions
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
Interventions
Morning Bright Light Therapy
Other
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Portand, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 3, 2026, 11:27 PM EDT
Recruiting Not applicable Interventional

Light Therapy to Improve Sleep in TBI: Sleep-active Biomarkers and Glymphatic Function

NCT07601841
View directory record Official record
Conditions
Sleep, Phototherapy, Glymphatic System, Mitochondrial Dynamics, Brain Injuries, Traumatic, Inflammation
Interventions
Morning Bright Light Therapy, Negative Ion Generator Therapy
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional

A Pilot Test of Mood and Circadian Rhythm Mechanisms Driving Binge Eating

NCT03680989
View directory record Official record
Conditions
Eating Disorder, Binge Eating, Circadian Dysregulation
Interventions
Bright Light Exposure, Natural Light Exposure
Device
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years and older · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

A Wearable Morning Light Treatment for Postpartum Depression

NCT04845347
View directory record Official record
Conditions
Post Partum Depression
Interventions
Bright Light Therapy, Dim Light Therapy
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Recruiting Not applicable Interventional

Improving Cognitive Rehabilitation Outcomes

NCT07055633
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions
CCT+MBLT, CCT+ION
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
San Diego, California • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

Morning Light Treatment at Home to Reduce PTSD Symptoms

NCT03513848
View directory record Official record
Conditions
PTSD
Interventions
Retimer, Retimer placebo
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Sep 3, 2026, 11:27 PM EDT
Recruiting Not applicable Interventional

Mechanisms of Risky Alcohol Use in Young Adults: Linking Sleep to Reward- and Stress-Related Brain Function

NCT05684094
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Sleep extension and advance, Regular sleep duration and timing
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 24 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nighttime Synchrony of Your Nutrition and Circadian Health

NCT07329283
View directory record Official record
Conditions
Sleep, Metabolism Changes, Circadian Rhythm, Lifestyle Factors, Sleep Hygiene, Sleep Hygiene, Inadequate, Sleep Deprivation, Insufficient Sleep, Circadian Misalignment, Circadian Dysregulation, Light Exposure
Interventions
Central Clock Misalignment, Peripheral Misalignment
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Enrolling by invitation Phase 2 Interventional

Bright Light Therapy for Depressed Geriatric Inpatients

NCT07002554
View directory record Official record
Conditions
Unipolar Depression
Interventions
Bright light therapy, dim red light
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Recruiting Not applicable Interventional

Bright Light Exposure in Surgical Patients

NCT03822949
View directory record Official record
Conditions
Myocardial Ischemia, Critical Illness, Endothelial Dysfunction
Interventions
Day Light, Placebo light, ICU Intense Light, ICU Placebo light
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 3, 2026, 11:27 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Blue Light Therapy for Liver Surgery

NCT02915081
View directory record Official record
Conditions
Acute Kidney Injury, Liver Injury, Inflammation
Interventions
Blue light
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

Pilot Trial of Phototherapy for Acute Depression in Hospitalized Cystic Fibrosis Patients

NCT01822197
View directory record Official record
Conditions
Depression, Cystic Fibrosis
Interventions
Phototherapy
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2016 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

Personalized Integrated Chronotherapy for Perinatal Depression

NCT04364646
View directory record Official record
Conditions
Depression, Postpartum Depression, Prenatal Disorder, Circadian Dysregulation, Pregnancy Related, Sleep Disturbance
Interventions
Personalized Integrated Chronotherapy
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Glen Oaks, New York • Chapel Hill, North Carolina • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury

NCT02374918
View directory record Official record
Conditions
Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
Interventions
mTBI wavelength-1 bright light, mTBI wavelength-2 bright light, HC wavelength-1 bright light, HC wavelength-2 bright light
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 23, 2021 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

A Non-Pharmacological Method for Enhancing Sleep in PTSD

NCT02370173
View directory record Official record
Conditions
PTSD, Sleep Problems
Interventions
PTSD wavelength-1 bright light, PTSD wavelength-2 bright light
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional

A Randomized Crossover Trial of Bright Light Therapy in Irritable Bowel Syndrome

NCT06676488
View directory record Official record
Conditions
Irritable Bowel Syndrome (IBS), Circadian Misalignment
Interventions
Re-Timer glasses, Placebo Device
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 3, 2026, 11:27 PM EDT
Completed Not applicable Interventional Results available

Bright Light Treatment At Home To Manage Chronic Pain In U.S. Veterans

NCT02373189
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Bright light
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Sep 3, 2026, 11:27 PM EDT