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Showing 1–24 of 95 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Morning light treatment Clear all
Completed Not applicable Interventional

A Randomized Crossover Trial of Bright Light Therapy in Irritable Bowel Syndrome

NCT06676488
View directory record Official record
Conditions
Irritable Bowel Syndrome (IBS), Circadian Misalignment
Interventions
Re-Timer glasses, Placebo Device
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Terminated Not applicable Interventional Results available

Prevention of Delirium After Bone Marrow Transplantation

NCT01700816
View directory record Official record
Conditions
Delirium
Interventions
Bright light therapy, Sham light
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional

Light Therapy for Obsessive-compulsive Disorder (OCD)

NCT05391503
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Light therapy, Placebo light therapy
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 35 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 5, 2026, 9:30 AM EDT
Recruiting Not applicable Interventional

Sleep and Circadian Interventions for College Students at High Risk of Suicide

NCT07346014
View directory record Official record
Conditions
Sleep Disturbance, Sleep, Depression, Suicide
Interventions
Sleep Feedback + Psychoeducation, Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+), Triple Chronotherapy (TCT+)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 25 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Phase 2 Interventional

RECOVER-SLEEP: Platform Protocol

NCT06404086
View directory record Official record
Conditions
Long COVID, Long COVID-19, Hypersomnia, Sleep Disturbance
Interventions
Modafinil, Modafinil Placebo, Solriamfetol, Solriamfetol Placebo, Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo
Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
47
States / cities
Phoenix, Arizona • Tucson, Arizona • Palo Alto, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Phase 2 Interventional Results available

Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration

NCT02564978
View directory record Official record
Conditions
Age-Related Macular Degeneration
Interventions
Minocycline
Drug
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
55 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 5, 2026, 9:30 AM EDT
Recruiting Not applicable Interventional

Phase 2 - Rhythmic Light Therapy for Alzheimer's Disease Patients

NCT05016219
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Circadian-Effective Light, Rhythmic Light, Placebo Light, Placebo Rhythmic Light
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
55 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Menands, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Not yet recruiting Not applicable Interventional

Overnight TI in TLE

NCT07434986
View directory record Official record
Conditions
Temporal Lobe Epilepsy (TLE), Drug Resistant Epilepsy, Sleep
Interventions
Non-invasive Temporal Interference (TI) Stimulation Targeting Bilateral Hippocampi
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy and Light Therapy

NCT05337943
View directory record Official record
Conditions
Pulmonary Hypertension, Insomnia, Fatigue
Interventions
CBT-I, Bright Light Therapy
Behavioral · Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Sep 5, 2026, 9:30 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

NCT06104280
View directory record Official record
Conditions
Opioid Use Disorder, Sleep Disturbance
Interventions
Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test, Ecological Momentary Assessments, Actigraphy, DLMO, Melatonin Suppression Test
Other · Behavioral · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Recruiting Not applicable Interventional

A Study Of Auricular Transcutaneous Vagus Nerve Stimulation In Chronic Dizziness

NCT07420803
View directory record Official record
Conditions
Chronic Dizziness, Persistent Postural Perceptual Dizziness
Interventions
Sham Device, Auricular transcutaneous vagus nerve stimulation
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Terminated Phase 2 Interventional Results available

Itacitinib (INCB039110) and Extracorporeal Photopheresis (ECP) for First-Line Treatment in Chronic GVHD

NCT04446182
View directory record Official record
Conditions
Chronic Graft-versus-host-disease
Interventions
Itacitinib, Extracorporeal Photopheresis (ECP)
Drug · Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 21, 2024 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional

Cognitive-behavioral Therapy vs. Light Therapy for Preventing SAD Recurrence

NCT01714050
View directory record Official record
Conditions
Seasonal Affective Disorder (SAD), Winter Depression, Major Depressive Disorder, Recurrent, With Seasonal Pattern
Interventions
Cognitive-Behavioral Therapy (CBT), Light Therapy (LT)
Behavioral · Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional

Light Therapy to Increase Energy in Adolescents and Young Adults Newly Diagnosed With Solid Tumors: A Pilot Study

NCT02429063
View directory record Official record
Conditions
Neoplasms, Fatigue
Interventions
Bright White Light, Dim Red Light
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
12 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional Results available

30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder

NCT01462305
View directory record Official record
Conditions
Seasonal Affective Disorder
Interventions
goLITE, Control
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 64 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
4
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Sep 5, 2026, 9:30 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans

NCT03968874
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Light box therapy, Negative Ion Generator
Device
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years to 88 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Phase 2 Interventional Results available

BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy.

NCT01658436
View directory record Official record
Conditions
Pancreatic Neuroendocrine Tumors (pNET)
Interventions
BEZ235 (Stage 1)
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
4
States / cities
Indianapolis, Indiana • Boston, Massachusetts • The Bronx, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2016 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional Results available

Personalized Integrated Chronotherapy for Perinatal Depression

NCT04364646
View directory record Official record
Conditions
Depression, Postpartum Depression, Prenatal Disorder, Circadian Dysregulation, Pregnancy Related, Sleep Disturbance
Interventions
Personalized Integrated Chronotherapy
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Glen Oaks, New York • Chapel Hill, North Carolina • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Physiology During Float-REST and the Consequential Effects on Subjective and Objective Recovery

NCT04415970
View directory record Official record
Conditions
Sleep Quality
Interventions
Flotation therapy sensory deprivation tank, Sleep Pod
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Phase 1 Interventional

Bright Light on Fatigue in Women Being Treated for Breast Cancer

NCT02658708
View directory record Official record
Conditions
Breast Neoplasms, Breast Cancer, Cancer of Breast, Cancer of the Breast
Interventions
Bright blue-green light using light visor cap, Dim red light using light visor cap, European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance, Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue, Digital foot candle datalogging light meter (Extech Instrument, Model SDL400), Polysomnography (Easy Ambulatory 2 Cadwell, Kennewick, WA), Horne-Ostberg Morningness-Eveningness Questionnaire, Daily Fatigue and Sleep Log
Other · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 5, 2026, 9:30 AM EDT
Active, not recruiting Not applicable Interventional

Flashed Light Therapy for Adolescents With ADHD and Delayed Sleep Timing

NCT06036420
View directory record Official record
Conditions
ADHD
Interventions
Flashed Light Therapy, Videoconference-delivered Cognitive Behavioral Therapy
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
14 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Phase 1 Interventional

A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies

NCT01470209
View directory record Official record
Conditions
Solid Tumors, Lung Cancer
Interventions
BKM120, Everolimus
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 18, 2018 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional

Alternative Treatments for Premenstrual Dysphoric Disorder

NCT01799733
View directory record Official record
Conditions
Premenstrual Dysphoric Disorder
Interventions
LWT+AM BWL, EWT+PM BWL
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 5, 2026, 9:30 AM EDT
Completed Not applicable Interventional

IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms

NCT06094608
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
Interventions
Morning light treatment, Treatment-as-usual
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 5, 2026, 9:30 AM EDT