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Conditions: Colorectal Cancer Control and Prevention
Interventions: single GPT generated message, AI Chatbot, Expert-Written Patient Materials; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 45 Years to 75 Years
Enrollment: 915 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Alcohol Use and Intimate Partner Violence
Interventions: Motivational Enhancement Therapy, Alcohol Education Control, Treatment as Usual, Strength at Home; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 3
States / cities: Boston, Massachusetts • Ann Arbor, Michigan • Minneapolis, Minnesota

Conditions: Vaccine Acceptance
Interventions: Peer-led vaccine education intervention; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: Not listed
Enrollment: 154 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
Interventions: Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual, Attention Control; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 7 Years to 85 Years
Enrollment: 292 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Tobacco Use, Parental Smoking
Interventions: Telephone Quitline Enrollment; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: Not listed
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Contraceptive Behavior, Sexually Transmitted Diseases
Interventions: follow-up phone counseling; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 14 Years to 18 Years · Female only
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Neonatal Intensive Care
Interventions: Motivational Interviewing, Treatment As Usual; Behavioral · Other
Lead sponsor: Johns Hopkins All Children's Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: NON APPLICABLE
Interventions: Diet Quality Matters (DQM) Nutrition Education and Culinary Skills Program; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Caries
Interventions: verbal education, verbal education, visual aids, and motivational interviewing; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: Up to 6 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Type1diabetes
Interventions: CB Sleep; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Type 2 Myocardial Infarction
Interventions: Clinician-level intervention, Patient-level intervention; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance-Related Disorders
Interventions: Brief intervention using motivational interviewing; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 868 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Substance Use Disorders
Interventions: SBIRT, SBIRT+RMC-PC; Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: 18 Years and older
Enrollment: 266 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 4
States / cities: Chicago, Illinois • Lansing, Illinois • Oak Park, Illinois

Conditions: Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder, Drinking, Alcohol, Substance Use
Interventions: Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI); Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Cincinnati, Ohio • Columbus, Ohio

Conditions: Diabetes Mellitus, Type 2, Diabetes Complications
Interventions: Diabetes Tune-Up Group; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 21 Years and older · Female only
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Binge Eating, Psychological, Health Behavior, Weight, Body
Interventions: Meditation, Mindful Motivation; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Oral Hygiene
Interventions: Motivational Interviewing; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 14 Years to 19 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Vista, California

Conditions: Alcohol Abuse
Interventions: MI/Family Check-up, MI only; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 13 Years to 17 Years
Enrollment: 208 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Unhealthy Alcohol Use
Interventions: Contingency Management Counseling, Addiction Physician Management, Motivational Enhancement Therapy; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 7
States / cities: Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 4 more

Conditions: Violence, Substance Use, Criminal Behavior, Violence in Adolescence
Interventions: Remote Therapy Intervention (RTI), Artificial Intelligence Remote Therapy Intervention; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years to 24 Years
Enrollment: 584 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 4
States / cities: Atlanta, Georgia • Detroit, Michigan • Flint, Michigan + 1 more

Conditions: Human Immunodeficiency Virus, Hepatitis C, Alcohol Abuse
Interventions: Computer-based alcohol reduction intervention, Brief clinician-delivered MET, Standard of care; Behavioral
Lead sponsor: New York University; Other
Eligibility: 21 Years to 45 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Hypertension, High Blood Pressure
Interventions: BPCARE Intervention; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 21 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 2
States / cities: San Diego, California

Conditions: Diabetes Mellitus, Type 2, Hypertension
Interventions: Motivational interviewing intervention arm; Behavioral
Lead sponsor: University of Houston; Other
Eligibility: 65 Years and older
Enrollment: 727 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Opioid Cessation
Interventions: Motivational Interviewing and Guided Opioid Tapering Support, Enhanced Usual Care; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 179 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

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Effect of Static vs. Conversational AI-Generated Messages on Colorectal Cancer Screening Intent: a Randomized Controlled Trial

Adjunctive Motivational Alcohol Intervention to Prevent IPV

Peer Education as a Strategy to Promote Vaccine Acceptance

A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy

An Intervention to Address Parental Smoking During the Postpartum Hospitalization.

The Young Woman's Reach Project: Trial of an Intervention to Impact Contraceptive Behavior, Unintended Pregnancy, and Sexually Transmitted Infections (STIs) Among Adolescent Females

Feasibility, Acceptability, and Fidelity of Motivational Interviewing to Increase Maternal NICU Presence

Diet Quality Pilot Intervention in LA Safety Net

A Strategy to Prevent the Recurrence of Dental Disease in Children Receiving Dental Treatment With General Anesthesia

Health Behavior Intervention for Adults With Type 1 Diabetes

Enhancing Cardiac Rehabilitation Attendance After Secondary Myocardial Infarction Through Clinician Messaging and Motivational Calls

Brief Intervention in Primary Care for Problem Drug Use and Abuse

Recovery Management Checkups for Primary Care Experiment

The STop UNhealthy Substance Use Now Trial

Electronic Diabetes Tune-Up Group (eDTU) for African Americans

Mindful Motivation for Reducing Binge Eating

Oral Hygiene Intervention for Adolescents

Brief Intervention for Families of Teens Treated in the Emergency Department for an Alcohol-Related Event

Financial Incentives, Randomization With Stepped Treatment Trial

Using Re-inforcement Learning to Automatically Adapt a Remote Therapy Intervention (RTI) for Reducing Adolescent Violence Involvement

Computer-based Intervention for Alcohol-using HIV/HCV+ Women

Blood Pressure Care for Advancing Real-World Evidence (BPCARE)

Motivational Interviewing (MI) Intervention to Improve Adherence

Motivational Interviewing and Guided Opioid Tapering Support to Promote Postoperative Opioid Cessation