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ClinicalTrials.gov public records Last synced Nov 10, 2026, 1:42 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 129 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Motivational and Problem-Solving Clear all

Conditions: Short Interpregnancy Intervals, Maternal Health Disparities
Interventions: Joint contraceptive and couple communication education, Couple communication consultation with Interventionist to increase partner engagement and improve communication, Check-ins to support continued partner support & communication; Other
Lead sponsor: University of Tennessee Graduate School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Work-related Injury
Interventions: individual -Brief Motivational Intervention (BMI), Group (Group Problem Solving), Standard of Care (OSHA 10 Safety Cards); Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 325 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: HIV Seropositivity, Substance Use, STI, Stigma, Social
Interventions: Stigma counseling for PrEP use; Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years and older · Male only
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
Interventions: MET, ED; Behavioral
Lead sponsor: National Jewish Health; Other
Eligibility: 30 Years to 80 Years
Enrollment: 306 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2015
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: HIV Infections
Interventions: Focus Group, First Intervention Trial, Intervention Trial 2; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 24 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 3
States / cities: Los Angeles, California • New York, New York • Philadelphia, Pennsylvania

Conditions: Acute Coronary Syndrome
Interventions: Positive Psychology (PP), Motivational Interviewing (MI); Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Type 1 Diabetes
Interventions: FL3X: Flexible Lifestyle Empowering Change; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 13 Years to 16 Years
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 2
States / cities: Aurora, Colorado • Cincinnati, Ohio

Conditions: Tobacco Use Cessation
Interventions: Standard contest (1 month), Motivational and Problem-Solving, Extended Contests; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 1,318 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Diabetes Mellitus, Chronic Disease
Interventions: Text Messaging (TM), Health Coaching (HC), Enhanced Usual Care (EC); Behavioral
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years and older
Enrollment: 646 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 19
States / cities: Holly Springs, Mississippi • Bartlett, Tennessee • Covington, Tennessee + 2 more

Conditions: Inactivity
Interventions: Original Tailored Intervention, Enhanced Tailored Intervention; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 214 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Stroke, Hypertension
Interventions: Home BP Telemonitoring (HBPTM), Nurse Case Management (NCM); Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Current Smoker, Tobacco Smoking, Tobacco Use
Interventions: Ask-Advise-Connect (AAC), Text Messaging (TM), Motivation And Problem-Solving (MAPS), Quitline; Other · Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 12,009 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Adolescent Behavior, Dental Plaque, Gingivitis, Cognitive Change
Interventions: Cognitive behavioral intervention, Colgate smart toothbrush; Behavioral · Other
Lead sponsor: Howard University; Other
Eligibility: 14 Years to 17 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Posttraumatic Stress Disorder (PTSD), Depression
Interventions: STEPS UP, OUC; Behavioral
Lead sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 666 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 6
States / cities: Fort Carson, Colorado • Fort Stewart, Georgia • Fort Campbell, Kentucky + 3 more

Conditions: Hypertension, Family Relations
Interventions: Walk Together; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Opioid-use Disorder, Amphetamine Use Disorders
Interventions: Neurocognitive Empowerment for Addiction Treatment (NEAT), Active Control; Behavioral
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Smoking
Interventions: Telephone Counseling, Telephone Assessments; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 370 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Bipolar Disorder
Interventions: CARE; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Cranston, Rhode Island • Providence, Rhode Island

Conditions: Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
Interventions: Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions, Individual Adolescent Therapy Sessions; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 14 Years to 17 Years
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Psychosis Nos/Other
Interventions: Brief family engagement intervention for CHR, Treatment as usual (TAU); Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 13 Years to 18 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: East Providence, Rhode Island

Conditions: HIV, Depression
Interventions: Health and Wellness Combined Cognitive Behavioral Therapy and a Medication Management Algorithm, Enhanced Standard of Care; Behavioral
Lead sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group; Network
Eligibility: 12 Years to 24 Years
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 13
States / cities: Alhambra, California • La Jolla, California • Los Angeles, California + 9 more

Conditions: Opioid-use Disorder, Mental Health Conditions
Interventions: Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 567 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Autism Spectrum Disorder
Interventions: Engagement Intervention, Engagement + Coaching Intervention; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 12 Months to 24 Months
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 3
States / cities: Coral Gables, Florida • Tallahassee, Florida • Boston, Massachusetts

Conditions: Subjective Cognitive Complaints, Mild Cognitive Impairment
Interventions: Personalized Web-based training for EMMA app, Motivational Interviewing: Clinician Support; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 50 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Pullman, Washington

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Planning Together: A Couple-based, Multi-level Prenatal Contraceptive Education Program for Economically Marginalized Families

VALES+Tú: Targeting Psychosocial Stressors to Reduce Latino Day Laborers (LDL) Injury Disparities

Assessing the PrEP Care Cascade Among Black Men and Transwomen in the Southeastern US

Evaluating Behavioral Treatments to Improve Adherence to Continuous Positive Airway Pressure (CPAP) Therapy in People With Obstructive Sleep Apnea (The BREATHE Study)

Integrated Treatment of Marijuana Abuse for HIV+ Youth

Positive Psychology for ACS Patients: a Factorial Design Study

FL3X Study: An Adaptive Intervention to Improve Outcomes for Youth With Type 1 Diabetes (FL3X)

Quit and Win Contests to Improve Smoking Cessation Among College Students

The Management of Diabetes in Everyday Life Program

Culturally and Linguistically Adapted Physical Activity Intervention for Latinas

Practice-Based Trial of Home BP Telemonitoring Among Minority Stroke Survivors

Strategies to Connect Patients at Federally Qualified Health Clinics With Evidence Based Tobacco Cessation Treatment

Evaluating the Effectiveness of a Cognitive Behavioral Intervention (CBI)

Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial

Walk Together: A Family-Based Intervention for Hypertension In African Americans

Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder

Combined Treatment for Tobacco and Alcohol Use in Puerto Rico

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Open Trial

Culturally Informed Family Based Treatment of Adolescents: A Randomized Trial

A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis

IMPAACT 2002: Cognitive Behavioral Therapy and Medication Management for Treatment of Depression in US Youth With HIV

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions

Autism Adaptive Community-based Treatment to Improve Outcomes Using Navigators (ACTION) Network

Electronic Memory and Management Aid