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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Motivational interviewing for smoking cessation Clear all
Terminated Phase 4 Interventional Accepts healthy volunteers

Testing Pharmacological Therapies for Pregnant Smokers

NCT00224419
View directory record Official record
Conditions
Smoking, Pregnancy
Interventions
Motivational interviewing for smoking cessation, Cognitive behaviors therapy, CBT + NRT
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
2
States / cities
Durham, North Carolina • Fayetteville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Text Messaging to Engage and Retain Veterans in Smoking Cessation Counseling

NCT03177265
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Text messaging prior to first counseling call, Text-to-Enhance, Mail Notice, Telephone Counseling
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
San Diego, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Testing Methods of Self-persuasion Involving Cigarette Smoking

NCT02069483
View directory record Official record
Conditions
Smoking
Interventions
Motivational Interviewing, Tailored Feedback
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Sep 26, 2026, 10:38 AM EDT
Recruiting Phase 1Phase 2 Interventional

Overcoming Nicotine Dependence to Enable Quitting

NCT05513872
View directory record Official record
Conditions
Tobacco Use, Smoking Cessation, Smoking Behaviors, Nicotine Dependence, Nicotine Withdrawal
Interventions
Nicotine Replacement Therapy (NRT) Sampling, Practice Quitting (PQ) Counseling, Motivational Interviewing (MI) Counseling
Drug · Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Phase 2 Interventional

Combination Pharmacotherapy for Smoking Cessation Among Methadone Patients

NCT00060814
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Combined intervention
Other
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Testing Counseling Styles to Motivate Smokers to Quit

NCT01188018
View directory record Official record
Conditions
Smoking, Tobacco Use, Nicotine Dependence
Interventions
Brief Advice (BA), Motivational Interviewing (MI), Health Education (HE)
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 3, 2012 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Choices4Health: Intervention to Prevent Substance-exposed Pregnancy

NCT03633149
View directory record Official record
Conditions
Prenatal Alcohol Exposure, Prenatal Tobacco Exposure, Prenatal Marijuana Exposure
Interventions
Computer tablet-delivered C4H, Person-delivered C4H, Brief Advice
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PRIDE: Preventing Respiratory Illnesses During Childhood Study

NCT00927264
View directory record Official record
Conditions
Tobacco Smoke Pollution
Interventions
Motivational Interviewing Intervention for ETS Reduction, Educational Program for ETS Reduction
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
6 Months to 6 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Smoking Cessation Intervention for Thoracic Patients

NCT00580398
View directory record Official record
Conditions
Lung Cancer
Interventions
Smoking cessation counseling, varenicline
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Phase 4 Interventional Results available

Helping Those With Mental Illness Quit Smoking

NCT01783912
View directory record Official record
Conditions
Smoking, Nicotine Dependence, Mental Disorders
Interventions
Cognitive / Motivational Individual Sessions, Attention Control Individual Sessions, Nicotine Patch, Group Curriculum
Behavioral · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 28, 2016 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Results available

Nicotine Withdrawal Symptoms and Smoking Relapse

NCT01511614
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Transcranial Direct Current Stimulation, sham, Nicotine patch, Placebo patch, Varenicline Pill, Placebo pill, Motivational Interviewing
Device · Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Sep 26, 2026, 10:38 AM EDT
Completed No phase listed Observational

Tobacco Assessment and Intervention With Low-Income Persons Living With HIV-AIDS (PLWHA) in Community-Based AIDS Service Organizations

NCT01482923
View directory record Official record
Conditions
Tobacco Cessation, HIV, AIDS
Interventions
Treatment as usual, AIR (Aspirations, Inspiration, Respiration)
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 3, 2019 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Let's STOP Now Trial: Smoking in Trauma Orthopaedic Patients

NCT02428244
View directory record Official record
Conditions
Smoking, Tobacco, Fractures, Bone
Interventions
Motivational Interviewing, Motivational Interviewing + Follow-up
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 79 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV

NCT04505371
View directory record Official record
Conditions
HIV Infections, Smoking, Smoking Cessation
Interventions
Wellness Intervention for Smokers with HIV
Behavioral
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 26, 2026, 10:38 AM EDT
Recruiting Phase 2 Interventional

E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

NCT05722561
View directory record Official record
Conditions
Opioid Use Disorder, Cigarette Smoking
Interventions
Telehealth Motivational Counseling, Nicotine Replacement Product, National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).
Behavioral · Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 75 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 26, 2026, 10:38 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Working Inside for Smoking Elimination

NCT01122589
View directory record Official record
Conditions
Cigarette Smoking, Tobacco Smoking
Interventions
Motivational Interviewing/CBT, CONcise Tapes Reviewing Obstacles to healthy Living (CONTROL)
Behavioral · Other
Lead sponsor
Memorial Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Pawtucket, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 8, 2010 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combined Treatment for Tobacco and Alcohol Use in Puerto Rico

NCT00570804
View directory record Official record
Conditions
Smoking
Interventions
Telephone Counseling, Telephone Assessments
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Sep 26, 2026, 10:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Quitxt Mobile Text Messaging Cessation Research Study

NCT05958667
View directory record Official record
Conditions
Smoking Cessation
Interventions
Quitxt text messaging or Chat, Usual care
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 29 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Phase 3 Interventional

Hutchinson Study of High School Smoking

NCT00115882
View directory record Official record
Conditions
Smoking Cessation
Interventions
MI + CBST
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
16 Years to 20 Years
Enrollment
2,151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 23, 2016 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Sustaining Smoking Cessation in Smokers With Kids With Asthma

NCT00862368
View directory record Official record
Conditions
Asthma, Smoking Cessation
Interventions
PAM, PAM-Enhanced/Asthma Counseling Phone Calls, Follow-Up Phone Calls - Child Wellness Topic
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
573 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
5
States / cities
Fall River, Massachusetts • Pawtucket, Rhode Island • Providence, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2012 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Practice-Based Trial of Home BP Telemonitoring Among Minority Stroke Survivors

NCT02011685
View directory record Official record
Conditions
Stroke, Hypertension
Interventions
Home BP Telemonitoring (HBPTM), Nurse Case Management (NCM)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

A Peer Navigator Model to Improve Quit Attempts and Smoking Cessation Rates Among HIV-positive Smokers

NCT04327921
View directory record Official record
Conditions
HIV
Interventions
Peer navigation social support for smoking cessation, Standard Condition
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Sep 26, 2026, 10:38 AM EDT
Completed Not applicable Interventional

Increasing Digital Equity and Access Among Rural Patients (IDEA) Study

NCT05209451
View directory record Official record
Conditions
Smoking Cessation
Interventions
Digital, evidence-based behavioral health program for smoking cessation, Bluetooth enabled iPad, Coaching Support
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Sep 26, 2026, 10:38 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

NCT03315910
View directory record Official record
Conditions
Smoking Cessation
Interventions
Motivational Interviewing (MI), Nicotine Replacement Therapy (NRT), Nicotine Lozenge, Message Framing, saliva sample
Behavioral · Drug · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
807 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
18
States / cities
Los Angeles, California • Walnut Creek, California • La Grange, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 26, 2026, 10:38 AM EDT