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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Multi-Component Weight Loss Intervention Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

Engaging Motivation for the Prevention of Weight Regain

NCT01169428
View directory record Official record
Conditions
Obesity
Interventions
Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2013 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Technology-Based Intervention for the Reduction of Overweight and Obesity Among College Students

NCT02196012
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Intervention group, attention control condition
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 22 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Holistic Health Program for United Methodist Clergy

NCT01564719
View directory record Official record
Conditions
Obesity, Depression, Diabetes, Hypertension, Hypercholesterolemia
Interventions
Holistic health
Behavioral
Lead sponsor
Duke Clergy Health Initiative
Other
Eligibility
18 Years and older
Enrollment
1,114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 29, 2020 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Charge: A Text Messaging-based Weight Loss Intervention

NCT03254940
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Charge
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
534 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Sugar-sweetened Beverage Consumption in Overweight Adolescents

NCT00381160
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Reduction of sugar-sweetened beverage consumption
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
13 Years to 17 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2012 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Teaching Obesity Treatment Options to Adult Learners (TOTAL): A Multisite RCT

NCT05346575
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Teaching Obesity Treatments to Adult Learners (TOTAL), Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
West Los Angeles, California • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Feasibility of a Multi Component Intervention in Patients With Severe Dyspnea and Obesity

NCT03836547
View directory record Official record
Conditions
COPD, Emphysema, Lung Diseases
Interventions
Coaching and Weight Loss for patients with dyspnea, Active Control
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Partners in Health: A Couples-based Approach to Obesity Prevention

NCT02205281
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
California Polytechnic State University-San Luis Obispo
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Luis Obispo, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2020 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Results available

Lifestyle Modification and Liraglutide

NCT02911818
View directory record Official record
Conditions
Obesity
Interventions
CMS-recommended lifestyle counseling, Liraglutide 3.0mg, Portion-Controlled Diet, Placebo Oral Tablet, Phentermine 15 MG, Extension Study CMS-recommended lifestyle counseling
Behavioral · Drug · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Health-Smart for Weight Loss at UF Jax Clinics

NCT03418701
View directory record Official record
Conditions
Obesity
Interventions
Health Smart for Weight Loss
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 100 Years · Female only
Enrollment
683 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Feasibility and Impact of Yoga in Obesity

NCT05031221
View directory record Official record
Conditions
Yoga, Obesity, Weight Loss
Interventions
Yoga + behavioral weight loss
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 11, 2026, 2:08 PM EDT
Terminated Not applicable Interventional

Sustaining the Reach of a Scalable Weight Loss Intervention Through Financial Incentives

NCT04225234
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Financial incentives
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Sep 11, 2026, 2:08 PM EDT
Active, not recruiting Not applicable Interventional

Miro-randomized Trial for Optimizing a JITAI to Reduce Dietary Lapses in Obesity Treatment

NCT04784585
View directory record Official record
Conditions
Obesity
Interventions
JITAI Enhanced Education Intervention Option, JITAI Self-Efficacy Intervention Option, JITAI Motivation Intervention Option, JITAI Self-Regulation Intervention Option, JITAI Generic Risk Alert Intervention Option (Active Comparator), Online Behavioral Obesity Treatment, JITAI No Treatment Intervention Option
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 11, 2026, 2:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The ADAPT Trial: Adapting Evidence-Based Obesity Interventions in Community Settings

NCT06546696
View directory record Official record
Conditions
Childhood Obesity
Interventions
Competency Based Approaches to Community Health (COACH)
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
6 Years to 12 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Precision Nutrition Impact on Health-Related Behavior Change

NCT04959318
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Professional nutrition counseling, No professional nutrition counseling
Other
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 45 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional

A Multi-Component Weight Loss Intervention to Improve Outcomes of Total Knee Replacement

NCT05853497
View directory record Official record
Conditions
Arthropathy of Knee, Obesity
Interventions
Multi-Component Weight Loss Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
50 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional

Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults

NCT06284681
View directory record Official record
Conditions
Obesity, Prehypertension, Hypertension, PreDiabetes, Type 2 Diabetes, Dyslipidemia
Interventions
Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach, Augment with enhanced medical management
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Building an Evidence Base for Weight Loss Strategies Among Those With Chronic SCI-The GLB-SCI+

NCT03874988
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Weight Loss, Diet Modification
Interventions
Portion-Controlled Meals, Enhanced Self-Monitoring, GLB-SCI+
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program

NCT04302389
View directory record Official record
Conditions
Weight Loss
Interventions
myWW App, Virtual Workshops, and Private Facebook Group
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

NCT02706288
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Weight loss with very low fat plant-based diet and regular exercise
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional

A Test of Nutritional Interventions to Enhance Weight Loss Maintenance

NCT01065974
View directory record Official record
Conditions
Overweight, Obesity, Weight Loss Maintenance
Interventions
Behavior Therapy, Meal Replacements, Nutritrol
Behavioral · Dietary Supplement
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Sep 11, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Just-in-time Adaptive Intervention Messaging in a Digital Weight Loss Intervention for Young Adults

NCT05625061
View directory record Official record
Conditions
Obesity, Overweight, Overweight and Obesity
Interventions
Core Behavioral Weight Loss (BWL) Intervention, Behavior Change Technique 1 Message (Action Planning), Behavior Change Technique 2 Message (Discrepancy between Current Behavior and Goal), Behavior Change Technique 3 Message (Feedback on Outcome of Behavior), Behavior Change Technique 4 Message (Social Support), Behavior Change Technique 5 Message (Social Comparison), Behavior Change Technique 6 Message (Social Reward), Behavior Change Technique 7 Message (Focus on Past Success)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 39 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 11, 2026, 2:08 PM EDT