Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 27, 2026, 6:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–8 of 8 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Myopia, Astigmatism, Refractive Error
Interventions
OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Results available

Clinical Biocompatibility Evaluation of Contact Lens Coatings

NCT03034928
Conditions
Refractive Errors, Ametropia
Interventions
Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS, Contact lens with investigational coating 2
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Johns Creek, Georgia
Conditions
Refractive Errors
Interventions
LID018869+RepleniSH, LID018869+Biotrue, Biofinity+RepleniSH, PV+Biotrue
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Maitland, Florida
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluation of an Investigational Multi-Purpose Solution (MPS)

NCT00961051
Conditions
Study Focus is Healthy Contact Lens Wearers
Interventions
Investigational MPS, Opti-Free
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
9
States / cities
San Diego, California • Waipahu, Hawaii • Warrensburg, Missouri + 6 more
Withdrawn Not applicable Interventional

OPTI-FREE Family STUDY

NCT06592521
Conditions
Contact Lens Care
Interventions
OPTI-FREE EXPRESS MPDS and Alcon contact lens case, OPTI-FREE PureMoist MPDS and Alcon contact lens case, OPTI-FREE REPLENISH MPDS and Alcon contact lens case, Habitual contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
7 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Myopia
Interventions
Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 65 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Myopia
Interventions
Nelfilcon A contact lens, Etafilcon A contact lens, FID 107027 solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, Multi-purpose disinfection solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
3
States / cities
Maitland, Florida • Bloomington, Illinois • Memphis, Tennessee