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ClinicalTrials.gov public records Last synced Nov 8, 2026, 7:43 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Multi-component lifestyle intervention Clear all

Conditions: Multiple Sclerosis
Interventions: Behavioral Intervention for Physical Activity in MS (BIPAMS), Wellness for MS (WellMS); Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Eating Behavior
Interventions: Multi-Component eHealth Intervention, namely Healthy Online Parental Education (HOPE); Behavioral
Lead sponsor: Texas Tech University; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Pediatric Obesity, Type 2 Diabetes, Time Restricted Eating
Interventions: Time Limited Eating, Components Common to All Study Arms., Control, Continuous Glucose Monitor; Behavioral · Device
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 12 Years to 21 Years
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Diabetes Mellitus, Type 2, Prediabetic State, Sleep Initiation and Maintenance Disorders
Interventions: SHUTi, Patient Education; Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 22 Years to 79 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Obesity
Interventions: CMS-recommended lifestyle counseling, Liraglutide 3.0mg, Portion-Controlled Diet, Placebo Oral Tablet, Phentermine 15 MG, Extension Study CMS-recommended lifestyle counseling; Behavioral · Drug · Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 21 Years to 70 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sexual Assault, Sexual Harassment
Interventions: Junior Enlisted Component, Leadership Component, Social Marketing Campaign; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Diabetes, Hypertension, Diabetic Kidney Disease
Interventions: Pharmacist telehealth intervention; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 285 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Schizophrenia, Obesity, Diabetes, Lifestyle Risk Reduction, Serious Mental Illness
Interventions: Multi-component Intervention for Diabetes in Adults with Serious Mental Illness; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Spinal Cord Injuries, Obesity, Weight Loss, Diet Modification
Interventions: Portion-Controlled Meals, Enhanced Self-Monitoring, GLB-SCI+; Behavioral
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obesity, Overweight
Interventions: Enriched lifestyle intervention; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 13 Years to 15 Years · Female only
Enrollment: 215 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Multiple Sclerosis
Interventions: MAPSS-MS, Usual Care plus computer games; Behavioral · Other
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 60 Years
Enrollment: 183 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Type 2
Interventions: Mediterranean Diet, Physical Activity, Stress Management, Social Support, Smoking Cessation, Control group; Behavioral · Other
Lead sponsor: Oregon Research Institute; Other
Eligibility: 30 Years to 75 Years · Female only
Enrollment: 273 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Obesity, Prehypertension, Hypertension, PreDiabetes, Type 2 Diabetes, Dyslipidemia
Interventions: Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach, Augment with enhanced medical management; Behavioral · Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents, Irregular Menstrual Cycle, Irregular Menstrual Cycles, Hirsutism, Hyperandrogenism
Interventions: Beef+; Other
Lead sponsor: Texas A&M University; Other
Eligibility: 11 Years to 17 Years · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: College Station, Texas

Conditions: Breast Cancer, Sedentary Lifestyle
Interventions: Common intervention components for Lifestyle; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Obesity & Overweight, Cardiometabolic Risk Factors
Interventions: Mediterranean eating style, Physical activity, Mindful Eating, Body Appreciation, Enjoyable Exercise; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obesity, Insulin Resistance
Interventions: Weight loss with very low fat plant-based diet and regular exercise; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 55 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Hypertension
Interventions: Self-Measured Blood Pressure Monitoring, Physician appointment and transportation scheduling; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Dysautonomia, Anxiety, Depression
Interventions: Transdiagnostic Group-Based Treatment; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 13 Years to 18 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Chronic Kidney Disease, Hypertension
Interventions: Multi-component lifestyle intervention, Usual Care Control; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Hypertension, Type 2 Diabetes Mellitus (T2DM)
Interventions: Coach-Directed Tailored DASH Groceries Plus Lifestyle Intervention, Self-Shopping DASH diet advice; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alcohol Consumption
Interventions: Brief Alcohol Intervention, Lifestyle brochures; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years and older
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Physical Activity, Sedentary Lifestyle
Interventions: Self-Monitoring, peer support and motivational prompts, Self-monitoring; Behavioral
Lead sponsor: Boston College; Other
Eligibility: 60 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Chestnut Hill, Massachusetts

Conditions: Overweight and Obesity
Interventions: Intervention group, attention control condition; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 18 Years to 22 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Knoxville, Tennessee

Search by objective public record fields.

Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis

Healthy Online Parental Education Project to Increase Fruit and Vegetable Intake and Active Playtime Among Toddlers

Time Limited Eating in Adolescents With Type 2 Diabetes (KT2D)

Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk

Lifestyle Modification and Liraglutide

Code of Respect (X-CoRe): Trial of a Multi-level Sexual Assault and Sexual Harassment Prevention Intervention for Active Duty Airmen

Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD)

Multi-component Intervention for Diabetes in Adults With Serious Mental Illness

Building an Evidence Base for Weight Loss Strategies Among Those With Chronic SCI-The GLB-SCI+

Examining the Feasibility of Collaborative Care Treatment for Overweight Adolescents

Computer Assisted Cognitive Rehabilitation for Persons With Multiple Sclerosis

Lifestyle Modification Program to Reduce Risk of Coronary Heart Disease in Latina Women With Diabetes

Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults

Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)

Developing a Healthy Lifestyle in Breast Cancer Survivors

Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

Reach Out 2: Emergency Department-Initiated Hypertension Mobile Health Intervention Connecting Multiple Health Systems

Implementation of Transdx Group for POTS

Lifestyle Intervention In CKD

Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes

Health Behavior Change for Hospitalized Veterans

Together we Move: A Multi-component Intervention to Increase Physical Activity for Ethnic Minority Older Adults

A Technology-Based Intervention for the Reduction of Overweight and Obesity Among College Students