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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Multifocal Contact Lens 2 Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population

NCT03581825
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal, etafilcon A Sphere
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
Orlando, Florida • East Lansing, Michigan • Raytown, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 7, 2020 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accommodative Relief for Uncomfortable Non-Presbyopes

NCT03544216
View directory record Official record
Conditions
Asthenopia
Interventions
Multifocal Contact Lens, Single Vision Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 40 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 3, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

VisionApp - Ghosting

NCT07571538
View directory record Official record
Conditions
Diplopia, Monocular
Interventions
Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens, MiSight 1 Day Contact Lens, Investigational Contact Lens, VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fitting Investigational Contact Lenses Phase 2

NCT03168542
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Fitting Guides
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens

NCT05765227
View directory record Official record
Conditions
Refractive Ametropia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses

NCT07076160
View directory record Official record
Conditions
Visual Acuity, Presbyopia
Interventions
INFUSE® One Day Multifocal, ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
7
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 3, 2026, 8:03 AM EDT
Active, not recruiting Phase 2 Interventional

Myopia Control: a Comparison Study Between Atropine and MiSight

NCT05815784
View directory record Official record
Conditions
Myopia
Interventions
Atropine, MiSight contact lenses
Drug · Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
5 Years to 12 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population Phase 2

NCT03586648
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal, etafilcon A Sphere
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
Whittier, California • Jacksonville, Florida • Maitland, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Sep 3, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses

NCT07638943
View directory record Official record
Conditions
Contact Lens Comfort and Successful Refitting, Presbyopia
Interventions
DAILIES TOTAL1 Multifocal (delefilcon A)
Device
Lead sponsor
Gordon Schanzlin New Vision
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Evaluating Two Multifocal Daily Disposable Contact Lenses

NCT05579886
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens, Test Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Ocoee, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss

NCT03653715
View directory record Official record
Conditions
Presbyopia
Interventions
Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens, Clerio Vision Single Vision Contact Lens
Device
Lead sponsor
Clerio Vision, Inc.
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types

NCT06232590
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens (comfilcon A), Test Lens (lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Granville, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Two Marketed Multifocal Contact Lenses

NCT03322423
View directory record Official record
Conditions
Visual Performance
Interventions
Multifocal Contact Lens 1, Multifocal Contact Lens 2, Spherical Contact Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
5
States / cities
Sarasota, Florida • Albuquerque, New Mexico • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Multifocal Contact Lens Designs With and Without an HEV Blocker on Visual Function

NCT04995055
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens TEST Lens, ACUVUE® OASYS Multifocal
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses

NCT05763628
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens (stenfilcon A), Test Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Vestal, New York • Athens, Ohio • Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Handling Comparison Between Two Contact Lens Types

NCT02310126
View directory record Official record
Conditions
Presbyopia
Interventions
etafilcon A (multi-focal), etafilcon A (sphere)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
8
States / cities
Jacksonville, Florida • Sarasota, Florida • Winter Park, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 3, 2026, 8:03 AM EDT
Recruiting Not applicable Interventional

Performance of Two Daily Disposable Multifocal Contact Lenses

NCT07444658
View directory record Official record
Conditions
Presbyopia
Interventions
Lens A (kalfilcon A), Lens B (stenfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 3, 2026, 8:03 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Myopia Progression With a Novel Extended Depth of Focus Contact Lens

NCT03358862
View directory record Official record
Conditions
Myopia, Myopia, Progressive
Interventions
NaturalVue Multifocal Contact Lens
Device
Lead sponsor
Aller, Thomas A., OD
Other
Eligibility
5 Years to 25 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Bruno, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Multifocal Toric Contact Lenses

NCT03208088
View directory record Official record
Conditions
Visual Acuity
Interventions
etafilcon A Investigational Toric Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
7
States / cities
Whittier, California • Orlando, Florida • Kahului, Hawaii + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 3, 2026, 8:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

NCT06335212
View directory record Official record
Conditions
Myopia, Refractive Errors, Contact Lens
Interventions
Single vision and multifocal contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses

NCT05886907
View directory record Official record
Conditions
Refractive Errors, Presbyopia, Astigmatism
Interventions
Lehfilcon A multifocal toric contact lenses, Samfilcon A multifocal toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Silicone Hydrogel Multifocal Contact Lenses

NCT04093258
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1® Multifocal Contact Lenses, Air Optix® Multifocal Contact Lenses Plus HydraGlyde®
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Roswell, Georgia • Granville, Ohio • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Sep 3, 2026, 8:03 AM EDT
Completed Not applicable Interventional Results available

Comparison of Two Soft Bifocal Contact Lenses

NCT00724945
View directory record Official record
Conditions
Presbyopia
Interventions
balafilcon A, senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
35 Years to 70 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
6
States / cities
Jacksonville, Florida • Winter Park, Florida • East Lansing, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated May 20, 2015 · Synced Sep 3, 2026, 8:03 AM EDT