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ClinicalTrials.gov public records Last synced Oct 20, 2026, 3:15 PM EDT

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Showing 1–24 of 93 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Multifocal contact lens Clear all
Completed Not applicable Interventional Results available

Assessing Fitting Guides in Alcon Multifocal Contact Lenses

NCT03118934
View directory record Official record
Conditions
Presbyopia, Refractive Errors
Interventions
Lotrafilcon B multifocal contact lenses, Nelfilcon A multifocal contact lenses, Delefilcon A multifocal contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years to 65 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
14
States / cities
Phoenix, Arizona • San Diego, California • Pensacola, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Oct 20, 2026, 3:15 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Evaluation of a Toric Multifocal Contact Lens Manufactured in Etafilcon Material in a Low ADD Hyperopic Population

NCT03713281
View directory record Official record
Conditions
Visual Acuity
Interventions
Toric Multifocal etafilcon A with PVP
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 20, 2026, 3:15 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Visual Performance With Contact Lenses

NCT03705130
View directory record Official record
Conditions
Myopia
Interventions
Single Vision Contact Lens, Multifocal Contact Lens 1, Multifocal Contact Lens 2
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 39 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accommodative Behaviors in Multifocal Contact Lenses

NCT06064617
View directory record Official record
Conditions
Accommodation Disorder
Interventions
Center-Near (+2.50D) Coopervision Biofinity Multifocal Contact Lens, Center Distance (+2.50 D) Coopervision Biofinity Multifocal Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 20, 2026, 3:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses

NCT07638943
View directory record Official record
Conditions
Contact Lens Comfort and Successful Refitting, Presbyopia
Interventions
DAILIES TOTAL1 Multifocal (delefilcon A)
Device
Lead sponsor
Gordon Schanzlin New Vision
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

NCT06377488
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
15
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Results available

Initial Performance of a Daily Disposable Contact Lens Featuring Molded Marks

NCT02939170
View directory record Official record
Conditions
Refractive Error
Interventions
Delefilcon A Multifocal Contact Lenses with Molded Mark, Delefilcon A Multifocal Contact Lenses
Device
Lead sponsor
Alcon, a Novartis Company
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Results available

Proclear 1-D Multifocal Nondispensing Study

NCT01526902
View directory record Official record
Conditions
Presbyopia
Interventions
omafilcon A / PC 1-D MF, lotrafilcon B / Air Optix MF
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
40 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 7, 2014 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of an Investigational Multifocal Lens

NCT02223754
View directory record Official record
Conditions
Presbyopia
Interventions
lotrafilcon B, etafilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
371 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
20
States / cities
Montgomery, Alabama • Mission Viejo, California • Jacksonville, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fitting Investigational Contact Lenses Phase 2

NCT03168542
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Fitting Guides
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 19, 2018 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Rotation With a Multifocal Toric Contact Lens

NCT05433571
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fitting Investigational Contact Lenses

NCT03150485
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Fitting Guides
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 29, 2018 · Synced Oct 20, 2026, 3:15 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial

NCT05159765
View directory record Official record
Conditions
Myopia
Interventions
Single vision contact lenses, Multifocal contact lenses
Device
Lead sponsor
Visioneering Technologies, Inc
Industry
Eligibility
7 Years to 13 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
4
States / cities
Fresno, California • Deerfield, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 20, 2026, 3:15 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control

NCT04080128
View directory record Official record
Conditions
Myopia
Interventions
Contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
10 Years to 15 Years
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Multifocal Soft Contact Lens Study

NCT06172881
View directory record Official record
Conditions
Myopia
Interventions
Investigational Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia

NCT05325931
View directory record Official record
Conditions
Presbyopia
Interventions
kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05101252
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A C3, Dailies Total 1 Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Roswell, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2023 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Performance of Investigational Contact Lenses in a Presbyopic Population

NCT01763047
View directory record Official record
Conditions
Presbyopia
Interventions
etafilcon A, lotrafilcon B
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
19
States / cities
Mission Viejo, California • Jacksonville, Florida • Saint Augustine, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 20, 2026, 3:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

VisionApp - Ghosting

NCT07571538
View directory record Official record
Conditions
Diplopia, Monocular
Interventions
Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens, MiSight 1 Day Contact Lens, Investigational Contact Lens, VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 20, 2026, 3:15 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Myopia Progression With a Novel Extended Depth of Focus Contact Lens

NCT03358862
View directory record Official record
Conditions
Myopia, Myopia, Progressive
Interventions
NaturalVue Multifocal Contact Lens
Device
Lead sponsor
Aller, Thomas A., OD
Other
Eligibility
5 Years to 25 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Bruno, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 20, 2026, 3:15 PM EDT
Recruiting Not applicable Interventional

Comparison of Hand Eye Coordination and Sports Vision Performance in Dual-Focus Multifocal Contact Lenses and Habitual Contact Lenses

NCT07840209
View directory record Official record
Conditions
Myopia
Interventions
Multifocal Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 38 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 20, 2026, 3:15 PM EDT
Active, not recruiting Phase 2 Interventional

Myopia Control: a Comparison Study Between Atropine and MiSight

NCT05815784
View directory record Official record
Conditions
Myopia
Interventions
Atropine, MiSight contact lenses
Drug · Device
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
5 Years to 12 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 20, 2026, 3:15 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Can Distance Center and Near Center Multifocal Contact Lenses Control Myopia Progression in Children?

NCT03519490
View directory record Official record
Conditions
Myopia, Myopia, Progressive
Interventions
Hybrid Contact Lens
Device
Lead sponsor
Thomas A. Aller, OD
Other
Eligibility
7 Years to 14 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Bruno, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 20, 2026, 3:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses

NCT02719366
View directory record Official record
Conditions
Presbyopia
Interventions
comfilcon A Extended Range test lens, comfilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 20, 2026, 3:15 PM EDT