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ClinicalTrials.gov public records Last synced Sep 22, 2026, 7:49 AM EDT

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Showing 1–24 of 92 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population

NCT04534517
Conditions
Visual Acuity
Interventions
JJV Investigational Multifocal Contact Lens, ACUVUE OASYS® with HYDRACLEAR® PLUS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
11
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Completed Not applicable Interventional Results available

Evaluating Two Multifocal Daily Disposable Contact Lenses

NCT05579886
Conditions
Presbyopia
Interventions
Control Lens, Test Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Ocoee, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Multifocal Soft Contact Lens Study

NCT06172881
Conditions
Myopia
Interventions
Investigational Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accommodative Relief for Uncomfortable Non-Presbyopes

NCT03544216
Conditions
Asthenopia
Interventions
Multifocal Contact Lens, Single Vision Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 40 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia

NCT05325931
Conditions
Presbyopia
Interventions
kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Rochester, New York
Conditions
Accomodation, Biofeedback Training, Myopia
Interventions
Auditory biofeedback traing
Behavioral
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
8 Years to 15 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Long Beach, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Performance of Verofilcon A Toric Contact Lenses

NCT07586982
Conditions
Contact Lenses, Presbyopia
Interventions
Total 30 multi foric contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Memphis, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Rotation With a Multifocal Toric Contact Lens

NCT05433571
Conditions
Visual Acuity
Interventions
Test Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 2 more
Conditions
Presbyopia
Interventions
Comfilcon A lens (test), Omafilcon B lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Bloomington, Indiana
Recruiting Not applicable Interventional Accepts healthy volunteers

VisionApp - Ghosting

NCT07571538
Conditions
Diplopia, Monocular
Interventions
Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens, MiSight 1 Day Contact Lens, Investigational Contact Lens, VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss

NCT03653715
Conditions
Presbyopia
Interventions
Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens, Clerio Vision Single Vision Contact Lens
Device
Lead sponsor
Clerio Vision, Inc.
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Rochester, New York
Conditions
Astigmatism, Myopia
Interventions
Contact lenses (Orthokeratology), Contact lenses (Soft Multifocal)
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 39 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Visual Acuity With a Reusable Toric Multifocal Contact Lens

NCT05000164
Conditions
Visual Acuity
Interventions
Bausch + Lomb Ultra® Multifocal for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
9
States / cities
Jacksonville, Florida • Maitland, Florida • Decatur, Georgia + 4 more
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control

NCT03635528
Conditions
Visual Acuity
Interventions
Test Lens 1, Test Lens 2, Test Lens 3, Test Lens 4, Test Lens 5, Control Lens 1, Control Lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bloomington, Indiana
Completed No phase listed Observational Accepts healthy volunteers

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

NCT06335212
Conditions
Myopia, Refractive Errors, Contact Lens
Interventions
Single vision and multifocal contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Conditions
Astigmatism, Myopia
Interventions
Lens A ( comfilcon A), Lens B ( lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
New York, New York • Granville, Ohio • Corpus Christi, Texas
Conditions
Visual Acuity
Interventions
Toric Multifocal etafilcon A with PVP
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Myopia, Hyperopia, Presbyopia
Interventions
omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens, High ADD power somofilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Berkeley, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses

NCT02719366
Conditions
Presbyopia
Interventions
comfilcon A Extended Range test lens, comfilcon A control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Berkeley, California
Conditions
Presbyopia
Interventions
Investigational contact lens, PureVision contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Conditions
Presbyopia
Interventions
Control Lens (comfilcon A), Test Lens (lehfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
4
States / cities
Medina, Minnesota • Vestal, New York • Granville, Ohio + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Performance of 1 Day Multifocal Contact Lenses

NCT04449263
Conditions
Presbyopia
Interventions
Lens A, Lens B, Habitual Lenses
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
5
States / cities
San Diego, California • Whittier, California • Sarasota, Florida + 2 more
Completed No phase listed Observational Accepts healthy volunteers Results available

Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control

NCT04080128
Conditions
Myopia
Interventions
Contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
10 Years to 15 Years
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Conditions
Presbyopia
Interventions
Control Lens (stenfilcon A), Test Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Vestal, New York • Athens, Ohio • Bellaire, Texas