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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:38 PM EDT

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Showing 289–312 of 592 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Multimodal Clear all
Completed Not applicable Interventional Results available

A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression

NCT01604512
View directory record Official record
Conditions
Brain Cancer
Interventions
MRI perfusion and PET/CT scans
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
6
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Not applicable Interventional Results available

Treating Chronic Pain in Gulf War Illness

NCT02378025
View directory record Official record
Conditions
Chronic Pain, Gulf War Illness, Chronic Illness
Interventions
Yoga Group, Pain Management Wellness Group
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
42 Years to 85 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2020 · Synced Oct 23, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The SENTINL-1 Study: Evaluating Patient-Reported Outcomes of AI-Inferred Lung Cancer Risk

NCT07458425
View directory record Official record
Conditions
Lung Cancer
Interventions
Artificial Intelligence (AI) test, Research-use-only multimodal AI risk model
Diagnostic Test
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional

M2VA Pain Care Pathway

NCT06526143
View directory record Official record
Conditions
Pain, Substance Use, Opioid Misuse, Quality of Life
Interventions
M2VA Pain Care Pathway (M2VAPCP), Implementation Facilitation
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
1,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 23, 2026, 1:38 PM EDT
Withdrawn Not applicable Interventional

EpiCare@Home Validation Study for Focal Onset Seizures

NCT05738226
View directory record Official record
Conditions
Epilepsy, Seizures, Seizures, Focal, Seizure, Refractory
Interventions
EpiCare@Home, wearable multimodal seizure monitoring system
Device
Lead sponsor
Byteflies
Industry
Eligibility
12 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 23, 2026, 1:38 PM EDT
Terminated Phase 4 Interventional

Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study

NCT02202369
View directory record Official record
Conditions
Single Level Lumbar Decompression and Fusion Spine Surgery
Interventions
Multimodal Analgesia Treatment, Standard of Care Pain Management Protocol
Other
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Multimodal Magnetoencephalography and Electroencephalography Exploration of the Acute Effects of THC Exposure on Neural Noise and Information Transmission Within Working Memory Networks

NCT05641766
View directory record Official record
Conditions
THC
Interventions
THC, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Not applicable Interventional

Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain

NCT04494698
View directory record Official record
Conditions
Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
Interventions
Duotherm VibraCool Back Device, TENS 8-channel unit
Device
Lead sponsor
MMJ Labs LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Landover, Maryland • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 23, 2026, 1:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detecting an MCI and Amyloid Digital Neuro Signature(DNS) Using Altoida's Multimodal Digital Biomarkers.

NCT06223438
View directory record Official record
Conditions
Alzheimer Disease, MCI
Interventions
Not listed
Lead sponsor
Altoida
Industry
Eligibility
50 Years and older
Enrollment
614 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Phase 2 Interventional

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

NCT00003955
View directory record Official record
Conditions
Sarcoma
Interventions
dactinomycin, filgrastim, pegfilgrastim, sargramostim, cyclophosphamide, irinotecan hydrochloride, vincristine sulfate, radiation therapy
Biological · Drug · Radiation
Lead sponsor
Children's Oncology Group
Network
Eligibility
Up to 49 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2009
U.S. locations
209
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 151 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2014 · Synced Oct 23, 2026, 1:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability

NCT04321200
View directory record Official record
Conditions
Pediatric ALL, Infant Development, Neurodevelopmental Disorders
Interventions
PANDA Gym, Mobile App
Diagnostic Test · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
0 Months to 6 Months
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Completed No phase listed Observational

Multimodal Approach to Testing the Acute Effects of Mild Traumatic Brain Injury (mTBI)

NCT02069613
View directory record Official record
Conditions
Concussion, Mild
Interventions
Not listed
Lead sponsor
Huntington Medical Research Institutes
Other
Eligibility
18 Years to 50 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Oct 23, 2026, 1:38 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Muscle Aging Phenotypes in Childhood Cancer Survivors

NCT07531498
View directory record Official record
Conditions
Muscle Weakness, Low Muscle Mass, Sarcopenia
Interventions
Multimodal Muscle Imaging and Functional Assessment, Multimodal Muscle Imaging and Neuromuscular Assessment, Comprehensive Muscle Phenotyping, Integrated Neuromuscular and Imaging Evaluation
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
533 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cessation Clinical Trial

NCT06806098
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Truth Initiative Digital Cessation Program, Usual Care
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
1,555 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Not yet recruiting Phase 1 Interventional

Study Evaluating 68GA-FAPI-46 PET/CT in Patients With Interstitial Lung Disease

NCT07817563
View directory record Official record
Conditions
Interstitial Lung Disease
Interventions
⁶⁸Ga-FAPI-46, PET/CT
Drug · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Active, not recruiting Early Phase 1 Interventional

Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression

NCT05683964
View directory record Official record
Conditions
Prostate Adenocarcinoma, Prostate Cancer, Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Interventions
Apalutamide [Erleada], darolutamide [Nubeqa], or enzalutamide [Xtandi], Prostate-Specific Membrane Antigen (PSMA) PET/CT Scan
Drug · Diagnostic Test
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
40 Years and older · Male only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Recruiting Not applicable Interventional

Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures

NCT05415384
View directory record Official record
Conditions
Pain, Postoperative, Rib Fracture Multiple
Interventions
Cryoablation of Intercostal Nerves, Standard surgical treatment of patients with multiple rib fractures
Device · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 23, 2026, 1:38 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults

NCT05258981
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
MRI
Diagnostic Test
Lead sponsor
Boston Children's Hospital
Other
Eligibility
24 Years to 35 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery

NCT04710277
View directory record Official record
Conditions
Postoperative Pain, Narcotic Use, Cryotherapy Effect
Interventions
Opioid-sparing multimodal pain management, Usual care
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 23, 2026, 1:38 PM EDT
Terminated Phase 1 Interventional

Multimodal Imaging Outcome Measures for ALS (Image ALS)

NCT04490096
View directory record Official record
Conditions
ALS
Interventions
[11C]-PBR28
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Dopaminergic Mechanisms Underlying Human Social Behavior

NCT04205994
View directory record Official record
Conditions
Decision Making, Executive Function, Dopamine
Interventions
Tolcapone 200 MG, Functional Magnetic Resonance Imaging (fMRI)
Drug · Other
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 40 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation

NCT03068611
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Standard Web-based Smoking Cessation, Alcohol-focused Web-Based Smoking Cessation
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 23, 2026, 1:38 PM EDT
Completed Phase 3 Interventional

A Phase 3 Study of F14 for Management of Pain Following Total Knee Replacement

NCT05603832
View directory record Official record
Conditions
Post Operative Pain
Interventions
F14, 0.25 % Bupivacaine HCl, Acetaminophen, Methocarbamol
Drug
Lead sponsor
Arthritis Innovation Corporation
Industry
Eligibility
45 Years to 80 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Little Rock, Arkansas • Tamarac, Florida • Tulsa, Oklahoma + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 23, 2026, 1:38 PM EDT
Not yet recruiting Not applicable Interventional

Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis.

NCT07831928
View directory record Official record
Conditions
Primary Progressive Multiple Sclerosis (PPMS), Secondary Progressive Multiple Sclerosis (SPMS)
Interventions
Online wellness course and online exercise platform, Usual Care Group
Behavioral · Other
Lead sponsor
University of Iowa
Other
Eligibility
45 Years to 70 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 23, 2026, 1:38 PM EDT