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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Muscle Cooling Clear all
Completed Not applicable Interventional

Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion

NCT03157349
View directory record Official record
Conditions
Acute Pain, Neck Pain
Interventions
Biofreeze, Placebo
Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Landover, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 12, 2026, 1:43 AM EDT
Recruiting Not applicable Interventional

Functional Balance Intervention in Multiple Sclerosis

NCT06341023
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Functional Balance Intervention, Stretching
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Palmar Cooling on the Human Immune System

NCT07215338
View directory record Official record
Conditions
Human Immune Response
Interventions
Muscle Temperature Control
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 12, 2026, 1:43 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Muscle Function Study

NCT04733287
View directory record Official record
Conditions
Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
Interventions
High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse, Sham Heat Therapy
Other
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 95 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 12, 2026, 1:43 AM EDT
Recruiting Not applicable Interventional

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

NCT04998916
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking, Substance Use, Drinking, Alcohol, Alcohol Use Disorder (AUD)
Interventions
Real TBS to the mPFC, Sham TBS to the mPFC
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Sep 12, 2026, 1:43 AM EDT
Withdrawn Not applicable Interventional

miRNA and Myokines in Patients With PAH

NCT03905083
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Exercise Rehab
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional

Resistance Training in HFpEF

NCT02435667
View directory record Official record
Conditions
Heart Failure Preserved Ejection Fraction
Interventions
Resistance Exercise Training, DEXA bone scan, Cardiopulmonary Max Exercise Test, Quality of Life Questionnaire, Submaximal Exercise Test, Blood Draw
Other · Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Muscle Temperature on Muscle Growth and Breakdown: Cooling During Resistance Training

NCT05302791
View directory record Official record
Conditions
Exercise Training
Interventions
Muscle Cooling, Resistance Exercise
Device · Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 12, 2026, 1:43 AM EDT
Active, not recruiting Phase 4 Interventional

Biofreeze® vs. a Placebo on Chronic Low Back Pain Walking Gait Characteristics and Pain

NCT03888820
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Biofreeze, Placebo
Drug
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional

Knee Arthroplasty Rehabilitation Outcomes Study

NCT02426190
View directory record Official record
Conditions
Total Knee Arthroplasty, Rehabilitation
Interventions
Anti-gravity treadmill, PENS - neuro-muscular stimulation, Anti-gravity treadmill & PENS - neuro-muscular stimulation, Recumbent or Nu-step bike
Other
Lead sponsor
MedStar National Rehabilitation Network
Other
Eligibility
40 Years and older
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Results available

Balance Training for Elders With Heart Failure

NCT02566785
View directory record Official record
Conditions
Heart Failure
Interventions
Balance Intervention
Other
Lead sponsor
University of Nebraska
Other
Eligibility
65 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 24, 2023 · Synced Sep 12, 2026, 1:43 AM EDT
Recruiting Not applicable Interventional

Home Based Functional Balance Intervention for Multiple Sclerosis

NCT07355387
View directory record Official record
Conditions
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis (MS) Secondary Progressive, Multiple Sclerosis Acute and Progressive
Interventions
Multicomponent balance intervention consisting of four components including dual-tasking, functional strength, vestibular and dynamic balance., Stretching
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years to 90 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise for Brain Health in the Fight Against Alzheimer's Disease

NCT03727360
View directory record Official record
Conditions
Healthy Cognition
Interventions
Exercise Training, Flexibility Control
Other
Lead sponsor
University of Maryland, College Park
Other
Eligibility
60 Years to 80 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ACTIV- Exercise Intervention in Healthy Young Men

NCT00401791
View directory record Official record
Conditions
Insulin Resistance
Interventions
Exercise
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
25 Years to 35 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Cancer Survivorship With Pickleball

NCT06048822
View directory record Official record
Conditions
Cancer
Interventions
Pickleball
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Results available

Spinal Cord Injury Program in Exercise

NCT03925077
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Movement-to-Music, Standard Exercise Training
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Impacts of Parent-Child Interactive Activities

NCT04839861
View directory record Official record
Conditions
Emotional Regulation
Interventions
Mightier Family Games, Mightier online gameplay
Behavioral
Lead sponsor
Neuromotion Labs
Industry
Eligibility
6 Years to 12 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly

NCT01899586
View directory record Official record
Conditions
Elderly, Sedentary
Interventions
Regional Specific Training Stimulus (RSTS), Aerobic Exercise Regimen (AE)
Other
Lead sponsor
Duke University
Other
Eligibility
70 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Baton Rouge, Louisiana • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 3, 2014 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of Prehabilitation in Vulnerable Patients Undergoing Cystectomy for Bladder Cancer

NCT01840137
View directory record Official record
Conditions
Bladder Cancer
Interventions
Baseline Strength Test, Exercise
Other
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional

Daily Undulating Periodization Methods With Parkinson's Disease

NCT03867877
View directory record Official record
Conditions
Parkinson Disease, Weight-Lifting Exercise Program
Interventions
Periodized training with motor practice, Simple Periodized Training
Other
Lead sponsor
University of Miami
Other
Eligibility
40 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 12, 2026, 1:43 AM EDT
Completed Not applicable Interventional Results available

Effects of Exercise Training and Ketone Ester on Muscle Strength and Cardiovascular Response in Parkinson's Disease

NCT05948956
View directory record Official record
Conditions
Parkinson Disease
Interventions
Ketone Ester Beverage, Electrolyte Beverage, Cycling Intervention
Dietary Supplement · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
45 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 12, 2026, 1:43 AM EDT
Terminated Phase 4 Interventional

Biofreeze® vs. a Placebo on Knee Osteoarthritis Walking Gait Characteristics and Pain

NCT03888807
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Biofreeze, Placebo
Drug
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Sep 12, 2026, 1:43 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Examining the Impacts on In-School Behaviors of In-Home Videogame Play

NCT05260398
View directory record Official record
Conditions
Emotional Regulation, Problem Behavior, Irritable Mood
Interventions
Mightier Online Gameplay
Behavioral
Lead sponsor
Neuromotion Labs
Industry
Eligibility
6 Years to 11 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 12, 2026, 1:43 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Training for Older Adults

NCT05542758
View directory record Official record
Conditions
Age-Related Sarcopenia
Interventions
Total Body HIIT Program
Other
Lead sponsor
Creighton University
Other
Eligibility
65 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Sep 12, 2026, 1:43 AM EDT