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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:08 PM EDT

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Showing 553–576 of 646 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Muscle Strength Clear all
Recruiting No phase listed Observational

The APS Phenotyping Study

NCT06521502
View directory record Official record
Conditions
ARDS, Sepsis, Pneumonia
Interventions
Blood collection, Urine Collection, Nasal, oral, and rectal swabs, Stool collection, Heat Moisture Exchange Filter collection, Tracheal Aspirate sample collection, Non-bronchoscopic bronchoalveolar lavage (NBBAL), Surveys, Short physical performance battery, Hand grip strength, CNS Vital Signs, Muscle Ultrasound, Muscle Strength, Spirometry, Lung Diffusion Testing (DLCO), Chest CT Scan
Other · Procedure · Radiation
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
20
States / cities
Fresno, California • Palo Alto, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy

NCT00260442
View directory record Official record
Conditions
Sarcopenia, Cardiovascular Disease
Interventions
Resistance Training, Sedentary
Behavioral
Lead sponsor
Texas A&M University
Other
Eligibility
50 Years to 69 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2018
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 20, 2026, 10:08 PM EDT
Terminated Phase 2 Interventional Results available

Safety and Exercise Study of Two Doses of BMN 110 for Morquio A Syndrome

NCT01609062
View directory record Official record
Conditions
Mucopolysaccharidosis IVA, Morquio A Syndrome, MPS IVA
Interventions
BMN 110
Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
7 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
4
States / cities
Oakland, California • Chicago, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional

The Effect of Blood Flow Restriction Training on Muscle Atrophy Following Knee Surgery

NCT03035266
View directory record Official record
Conditions
Knee Injuries
Interventions
Blood Flow Restriction, Standard rehabilitation
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 50 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
West Point, New York • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2020 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia

NCT00499759
View directory record Official record
Conditions
Depression, Fatigue, Leukemia, Musculoskeletal Complications, Psychosocial Effects of Cancer and Its Treatment
Interventions
Resting vitals, Body Composition, Timed Get-up and Go test (TGUG)., Cardiorespiratory assessment, Handgrip evaluation, Dynamic muscular endurance
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2012 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

NCT04886518
View directory record Official record
Conditions
Myotonic Dystrophy 1, Excessive Daytime Sleepiness
Interventions
Pitolisant Oral Tablet, Placebo oral tablet
Drug
Lead sponsor
Harmony Biosciences Management, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
11
States / cities
Irvine, California • Aurora, Colorado • Tampa, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 20, 2026, 10:08 PM EDT
Not yet recruiting Not applicable Interventional

Inspiratory Muscle Strength Training in Adults With Type 1 Diabetes

NCT07859943
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
High-Resistance Inspiratory Muscle Strength Training, Sham Inspiratory Muscle Strength Training
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
2
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 20, 2026, 10:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Entorhinal Cortex and Aerobic Exercise in Aging

NCT02775760
View directory record Official record
Conditions
Aging
Interventions
Cardiovascular endurance, Strength, balance, and flexibility
Behavioral
Lead sponsor
Boston University
Other
Eligibility
60 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

PRIME: Pilot Study Evaluating Percutaneous Vaccination of BCG for Bladder Cancer

NCT02326168
View directory record Official record
Conditions
Bladder Cancer
Interventions
Bacillus Calmette-Guerin (BCG)
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional

EXERT-BCN: an Exercise and Nutrition Regimen to Designed to Improve Body Composition After Treatment for Breast Cancer

NCT05978960
View directory record Official record
Conditions
Breast Cancer
Interventions
Nutrition and resistance training exercise intervention
Other
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
20 Years to 89 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional Results available

Muscle Weakness and Post-traumatic Knee OA

NCT01879852
View directory record Official record
Conditions
Meniscectomy
Interventions
Quadriceps intensive strengthening, Standard rehabilitation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
15 Years to 35 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Oct 20, 2026, 10:08 PM EDT
Completed No phase listed Observational

Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit

NCT02270502
View directory record Official record
Conditions
Critical Illness, Sarcopenia, Muscle Wasting
Interventions
Ultrasound Philips CX50, Frailty Index Questionnaire, Muscle strength tests
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Phase 2 Interventional Results available

Dose Range Finding Study of Bimagrumab in Sarcopenia

NCT02333331
View directory record Official record
Conditions
Sarcopenia
Interventions
bimagrumab, placebo
Drug · Other
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
70 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
17
States / cities
Little Rock, Arkansas • Cypress, California • La Jolla, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 20, 2026, 10:08 PM EDT
Completed No phase listed Observational

Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes

NCT04319237
View directory record Official record
Conditions
Diffuse Large B Cell Lymphoma, Transformed Lymphoma
Interventions
Handgrip strength test, Neuropsychological Assessment - Wechsler Test of Adult Reading (WTAR), Neuropsychological Assessment - Repeatable Battery for the Assessment of Status (RBANS), Neuropsychological Assessment - Color Trails, Neuropsychological Assessment -Stroop Color and Word Test, Patient Reported Outcomes Measurement Information System-29 (PROMIS-29) Questionnaire, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire, Quality of Life (EQ-5D-5L) Questionnaire, PROMIS Cognitive Function 4a Questionnaire, Comprehensive Score for Financial Toxicity (COST) measure
Other · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 20, 2026, 10:08 PM EDT
Terminated Not applicable Interventional

Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit

NCT04160039
View directory record Official record
Conditions
Liver Cirrhoses, Liver Failure, ICU Acquired Weakness
Interventions
Cycle ergometry
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 20, 2026, 10:08 PM EDT
Withdrawn Not applicable Interventional

The Effects of Adding Expiratory Muscle Strength Training in Voice Therapy

NCT03692494
View directory record Official record
Conditions
Dysphonia, Unilateral Vocal Cord Paralysis
Interventions
Standard of care voice therapy, Expiratory muscle strength training (EMST)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Home-based vs. Supervised Exercise for People With Claudication

NCT00618670
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Walking Exercise, Control--Resistance Training
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
35 Years to 100 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 2, 2018 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Mental Effort and Muscle Strength

NCT00059436
View directory record Official record
Conditions
Aging, Muscle Strength
Interventions
Mental effort in muscle strengthening
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
65 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1999
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2016 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Covid-19 Virtual Recovery Study

NCT04950725
View directory record Official record
Conditions
Covid19
Interventions
Strength RMT, Strength RMT and nasal breathing, Endurance RMT, Endurance RMT and nasal breathing, Low dose RMT
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
2,268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy Study of Oral Fampridine-SR in Patients With Multiple Sclerosis

NCT00053417
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Placebo, 10 milligram (mg) fampridine-SR (4-aminopyridine, 4-AP), 15 mg fampridine-SR (4-aminopyridine, 4-AP), 20 mg fampridine-SR (4-aminopyridine, 4-AP)
Drug
Lead sponsor
Acorda Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003
U.S. locations
23
States / cities
Phoenix, Arizona • Los Angeles, California • New Haven, Connecticut + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2011 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional Results available

Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program

NCT00942890
View directory record Official record
Conditions
Traumatic Amputation
Interventions
NMES (EMPI 300PV stimulator) plus standard of care, TMARP standard of care
Device · Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
San Diego, California • Bethesda, Maryland • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Strive Cardio for Endometrial Cancer Survivors

NCT06534008
View directory record Official record
Conditions
Endometrial Cancer, Cardiovascular Diseases
Interventions
12-week home-based exercise intervention
Behavioral
Lead sponsor
Jess S. Gorzelitz
Other
Eligibility
18 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional

Identify Patients With Neck Pain Likely to Benefit From Education and Exercise

NCT01144884
View directory record Official record
Conditions
Neck Pain
Interventions
Procedure (education and exercise)
Other
Lead sponsor
William J. Hanney
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
9
States / cities
Altamonte Springs, Florida • Jacksonville, Florida • Kissimmee, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 20, 2026, 10:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women

NCT03888040
View directory record Official record
Conditions
Aging
Interventions
Exercise
Other
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 100 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 20, 2026, 10:08 PM EDT