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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Music Enhancement Clear all
Not yet recruiting Not applicable Interventional

The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms

NCT06701578
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Safe and Sound Protocol, Control
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 19, 2026, 1:41 PM EDT
Recruiting Not applicable Interventional

Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome

NCT03533985
View directory record Official record
Conditions
NAS
Interventions
Song of Kin, Gato box, Ocean disc, Contingent singing, Tonal Vocal holding, Muted shaker
Behavioral · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
28 Weeks and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
6
States / cities
New Orleans, Louisiana • Hackensack, New Jersey • New Hyde Park, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Infant Environment Study

NCT02936284
View directory record Official record
Conditions
Infant Development, Motivation
Interventions
Music Enhancement, Play Date
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
9 Months to 15 Months
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Sep 19, 2026, 1:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sensory Adapted Dental Environments to Enhance Oral Care for Children With and Without Dental Fear and Anxiety

NCT06912854
View directory record Official record
Conditions
Dental Fear and Anxiety
Interventions
Sensory Adapted Dental Environment, Video-based Modeling
Other
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 12 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 19, 2026, 1:41 PM EDT
Active, not recruiting Not applicable Interventional

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer

NCT05053230
View directory record Official record
Conditions
Head and Neck Cancer, Head and Neck Tumor, Thoracic Tumor, Thoracic Cancer, Gynecologic Cancer, Gynecologic Tumor, Melanoma, Ovarian Cancer
Interventions
IM@Home, Enhanced usual care
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Consciousness Studies and Cardiovascular Health

NCT07620639
View directory record Official record
Conditions
Blood Pressure, Relaxation, Virtual Reality
Interventions
Virtual Reality Relaxation, Video Meditation, Live Guided
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Active, not recruiting No phase listed Observational

A Digital Art Activity to Enhance Self-Disclosure and the Detection of Psycho-social Distress in Adult Cancer Patients

NCT06127121
View directory record Official record
Conditions
Cancer
Interventions
Digital Art Activity
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Wholetones® 2Sleep Music on Health and Sleep Behaviors of Healthy Adults With Insomnia Symptoms

NCT03928301
View directory record Official record
Conditions
Insomnia, Sleeplessness
Interventions
Wholetones Music, Classical Music
Behavioral
Lead sponsor
Jacksonville University
Other
Eligibility
25 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 19, 2026, 1:41 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Puerto Rican Obesity Intervention for Men

NCT06440551
View directory record Official record
Conditions
Obesity
Interventions
TeleSalud Healthy Eating- Physical Activity/Sedentary Behavior (HE-PA/SB), TeleSalud General Health Intervention
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
35 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Recruiting Not applicable Interventional

Mindfulness in Chronic Kidney Disease

NCT04099992
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Mindfulness-based stress reduction (MBSR), Health enhancement program (HEP), Transcutaneous Vagus Nerve Stimulation (tVNS), Sham-transcutaneous Vagus Nerve Stimulation (tVNS)
Behavioral · Device
Lead sponsor
Emory University
Other
Eligibility
40 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional Results available

Preventing Persistent Post-Surgical Pain and Opioid Use In At-Risk Veterans: Effect of ACT

NCT02437188
View directory record Official record
Conditions
Persistent Post-surgical Pain, Acceptance and Commitment Therapy, Substance Use Disorder
Interventions
ACT (Acceptance and Commitment Therapy)
Behavioral
Lead sponsor
Barbara A Rakel
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Audio-enhanced Analgesia in Healthy Subjects

NCT01835275
View directory record Official record
Conditions
Healthy
Interventions
Enhanced Audio, Audio
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2016 · Synced Sep 19, 2026, 1:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Moving Yourself in Space and Time: MYSTIC

NCT07697664
View directory record Official record
Conditions
Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders, Older Adults (60 - 85 Years Old)
Interventions
Complex Rhythmic Movement Sequences (CRMS) Sessions
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 79 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Not yet recruiting Phase 4 Interventional

Veterans Enhanced Recovery Using Integrative Treatments Around Surgery

NCT06333938
View directory record Official record
Conditions
Anesthesia, Surgery, Knee Arthropathy
Interventions
Nonpharmacologic Treatment, Standard Care
Other
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 19, 2026, 1:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Music Intervention on Sleep

NCT06088810
View directory record Official record
Conditions
Dementia
Interventions
CoMPoSER intervention group, Sleep Education
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Relaxation Music for Chronic Pain

NCT06993272
View directory record Official record
Conditions
IBS - Irritable Bowel Syndrome, IBD - Inflammatory Bowel Disease
Interventions
MIndful Jazz, Reggae Stereotypes, Traditional Mindfulness, Pain psychoeducation
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Delivering Early Intervention to Children With Down Syndrome

NCT03935620
View directory record Official record
Conditions
Down Syndrome
Interventions
Enhanced Milieu teaching
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Months to 36 Months
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Sep 19, 2026, 1:41 PM EDT
Recruiting Not applicable Interventional

VR-PMR for Post-Burn Symptoms

NCT07317271
View directory record Official record
Conditions
Burn, Chronic Pain Following Thermal Burn Injury, Non-Pharmacological Interventions, Virtual Reality, Sleep Disturbance, Anxiety, Depressive Symptoms, Fatigue Symptom, Pruritus, Burn Injury, Progressive Muscle Relaxation
Interventions
Virtual Reality-Enhanced Progressive Muscle Relaxation, Standard Progressive Muscle Relaxation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Music Therapy in the Treatment of Perioperative Anxiety and Pain

NCT05263635
View directory record Official record
Conditions
Pain, Post Operative, Anxiety, Opioid Use
Interventions
Music therapy, Standard of Care Enhanced Recovery After Surgery (ERAS)
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality to Enhance Upper Extremity Physical Therapy and Recovery

NCT05846464
View directory record Official record
Conditions
Injuries to the Hand and Wrist
Interventions
Meta Quest 2
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Single-Session Intervention Targeting Emotional Awareness, Clarity, and Acceptance to Reduce Depression/Anxiety

NCT05109507
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Visitor Mindset, Relaxing with Nature
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Well-being Interventions on Affect, Attention, Sleep, Social Stress and Pain Regulation

NCT01057368
View directory record Official record
Conditions
Health, Mental Health
Interventions
Day of intensive meditation practice, Mindfulness Based Stress Reduction (MBSR), Health Enhancement Program (HEP)
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
25 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
3
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Sep 19, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Music and Child Health and Development

NCT05868811
View directory record Official record
Conditions
Obesity, Infant, Language Development, Parent-Child Relations
Interventions
Music Together, Play Group
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
9 Months to 24 Months
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 19, 2026, 1:41 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Sleep, Dreaming, and Virtual Reality for Mental Health

NCT07408206
View directory record Official record
Conditions
Anxiety
Interventions
Dream Yoga Inspired Intervention, Sleep Health Enhancement Program (SHEP)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Evanston, Illinois • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 19, 2026, 1:41 PM EDT