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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:20 AM EDT

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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: N95 Respirator Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Free Air Portable Air Powered Respirator

NCT02487147
View directory record Official record
Conditions
Influenza
Interventions
Free Air Portable Air Powered Respirator, N95 Respirator
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 49 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2022 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

New Reusable Mask Design With Superior Filtration and Fit

NCT04826809
View directory record Official record
Conditions
Covid19, Tuberculosis, Respiratory Viral Infection
Interventions
N95 mask, Nordell single E-100 layer mask, Nordell double E-100 layer mask
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Mankato, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 21, 2026, 5:20 AM EDT
Not listed Not applicable Interventional

Quantifying Viral Load in Respiratory Particles That Are Generated by Children and Adults With COVID-19 Infection

NCT05195229
View directory record Official record
Conditions
COVID-19
Interventions
COVID-19 Aerosol Collection
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Respiratory Protection During Simulated Resuscitation: a Prospective Cohort Study

NCT04591756
View directory record Official record
Conditions
Occupational Exposure
Interventions
Qualitative Fit Testing
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 21, 2026, 5:20 AM EDT
Active, not recruiting Not applicable Interventional

Laying the Foundation for Building a Resilient KPNC Community in the Face of Worsening Air Quality Due to Wildfire Smoke

NCT07118189
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD), Exacerbation of COPD, Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions
N95 masks and indoor air cleaner
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Air Pollution: Strategies for Personalized Intervention to Reduce Exposure

NCT03744871
View directory record Official record
Conditions
Air Pollution
Interventions
N95 Respirator
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reusable, Transparent, and Reconfigurable N95-equivalent Respirator Masks: Design, Fabrication, and Trials for Enhanced Adoption

NCT07711145
View directory record Official record
Conditions
Focus is on Healthy Subjects
Interventions
Reusable, Transparent, and Reconfigurable N95-Equivalent Respirator Masks: Design, Fabrication, and Clinical Trials for Enhanced Adoption
Device
Lead sponsor
SEEUS95 Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Results available

The Respiratory Protection Effectiveness Clinical Trial

NCT01249625
View directory record Official record
Conditions
Influenza, Respiratory Syncytial Viruses, Paramyxoviridae Infections, Coronavirus, Rhinovirus
Interventions
N95 Respirator, Medical/surgical mask
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
2,862 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
7
States / cities
Aurora, Colorado • Denver, Colorado • Washington D.C., District of Columbia + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a N95 Respirator vs Cloth Mask on Exercise Capacity During Treadmill Exercise.

NCT04415879
View directory record Official record
Conditions
COVID-19
Interventions
N-95 Respirator, Cloth Face Mask
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 21, 2026, 5:20 AM EDT
Terminated Not applicable Interventional

Nasal Bridge Pressure Injury Prevention

NCT04761679
View directory record Official record
Conditions
Pressure Ulcer of Skin, Pressure Injury
Interventions
Applying the Mepilex foam
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 64 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 21, 2026, 5:20 AM EDT
Terminated No phase listed Observational

User Experience of the OSR M-1

NCT04733677
View directory record Official record
Conditions
Covid19
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
21 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 21, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Variation In Facial Morphology As A Determinant Of Face Covering Performance: FACEFIT

NCT05388201
View directory record Official record
Conditions
Healthy
Interventions
N95, KN95, KF94, Surgical
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment

NCT04416919
View directory record Official record
Conditions
Coronavirus Infection, Disease Prevention
Interventions
Assembled mask
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Just-in-time Elastomeric Training and Fit Testing (JET FIT)

NCT03888898
View directory record Official record
Conditions
Infection
Interventions
Reusable respirator fit test and competency evaluation, Control fit test evaluation
Other
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
3
States / cities
Atlanta, Georgia • Detroit, Michigan • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 21, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

N95 Reuse During COVID-19

NCT05148793
View directory record Official record
Conditions
Emergency Medicine, Frontline Providers, Healthcare Worker
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
412 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 21, 2026, 5:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Product Testing of the FaceView Mask™: Usability Survey

NCT04854694
View directory record Official record
Conditions
Hearing Disability
Interventions
FaceView Mask™, conventional surgical N95 respirator
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 21, 2026, 5:20 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Transparent Elastomeric Respirator for Aerosol-based Protection

NCT04511390
View directory record Official record
Conditions
Personal Protective Equipment
Interventions
Transparent, reusable respirator
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 21, 2026, 5:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Silica Exposure Among Brick Kiln Workers in Nepal

NCT06090370
View directory record Official record
Conditions
Silicosis
Interventions
N95 Respirator, Protective Eyewear, Baseline Survey, Design of Workshop, Training Workshop Pilot
Device · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
2
States / cities
Baltimore, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Oct 21, 2026, 5:20 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessment of Fit of Novel N95 Style Transparent Face Masks

NCT06570161
View directory record Official record
Conditions
Respiratory Disease, Infection, Coronavirus, Respiratory Tract Infections
Interventions
SEEUS95 Transparent mask, CrystalGuard Mask, N95 face mask
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 21, 2026, 5:20 AM EDT