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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Active, not recruiting Phase 3 Interventional

Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment

NCT05261399
View directory record Official record
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
Savolitinib, Osimertinib, Pemetrexed, Cisplatin, Carboplatin
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 130 Years
Enrollment
341 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
5
States / cities
Orlando, Florida • Honolulu, Hawaii • New Brunswick, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Child Care Wellness Study on Nutrition and Physical Activity

NCT01921842
View directory record Official record
Conditions
Overweight, Obesity
Interventions
NAP-SACC Child Care Wellness Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
2 Years to 5 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 12, 2013 · Synced Sep 4, 2026, 3:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Role of Naps and Overnight Sleep on Cognitive Learning in Preschoolers

NCT04758663
View directory record Official record
Conditions
Sleep
Interventions
Nap/wake conditions on memory, Nap/wake conditions on overnight physiology
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
33 Months to 71 Months
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Sep 4, 2026, 3:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Age-Related Changes in Sleep-Dependent Emotional Memory

NCT04141722
View directory record Official record
Conditions
Sleep, Age, Emotional Valence
Interventions
Overnight sleep, Wake
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2019 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder

NCT01163032
View directory record Official record
Conditions
Non-24-Hour Sleep-Wake Disorder
Interventions
tasimelteon, Placebo
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
23
States / cities
Phoenix, Arizona • Orange, California • Palo Alto, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2014 · Synced Sep 4, 2026, 3:57 AM EDT
Terminated Not applicable Interventional

The Nightmare Augmented Protocol for Treatment of Nightmares in Veterans With PTSD

NCT05120674
View directory record Official record
Conditions
PTSD
Interventions
NAP, CPT, ERRT, Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
VA Eastern Kansas
Federal
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Leavenworth, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2021 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Night Shift Nurses' Health and Reducing Burnout

NCT06829979
View directory record Official record
Conditions
Healthy
Interventions
Access to napping/relaxation room, Blue and green light blocking glasses
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 99 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 4, 2026, 3:57 AM EDT
Recruiting Phase 1 Interventional

A Vaccine (MV-s-NAP) for the Treatment of Patients With Invasive Metastatic Breast Cancer

NCT04521764
View directory record Official record
Conditions
Anatomic Stage IV Breast Cancer AJCC v8, Invasive Breast Carcinoma, Metastatic Breast Adenocarcinoma, Recurrent Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
Interventions
Oncolytic Measles Virus Encoding Helicobacter pylori Neutrophil-activating Protein, Computed Tomography, Magnetic Resonance Imaging, Biopsy, Biospecimen Collection
Biological · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Phase 2 Interventional

Effect of Activities and Exercise on Sleep in Elderly Persons With Dementia

NCT00888706
View directory record Official record
Conditions
Dementia, Elderly, Sleep
Interventions
Control Condition, Individualized Social Activities (ISA), Physical Resistance Training and Walking (PRT/walking), Combined ISA/PRT/walking
Behavioral
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
55 Years and older
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2009 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Phase 3 Interventional

Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception

NCT01429116
View directory record Official record
Conditions
Non-24-Hour Sleep-Wake Disorder
Interventions
tasimelteon
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
22
States / cities
Phoenix, Arizona • Orange, California • Palo Alto, California + 19 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2015 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Evolution of Memories Across Wake and Sleep

NCT03227406
View directory record Official record
Conditions
Sleep Deprivation, Sleep
Interventions
Sleep deprivation, Nap
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Sep 4, 2026, 3:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Artemis Sleep Countermeasures

NCT06531733
View directory record Official record
Conditions
Fatigue
Interventions
Sleep Promoting (pink noise), Wake Promoting (blue enriched light plus a nap)
Device
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Sep 4, 2026, 3:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

NCT03767426
View directory record Official record
Conditions
Sleep Deprivation, Sleep
Interventions
Sleep Deprivation, Daytime nap
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Not applicable Interventional

CBT-I for Sleep, Pain, and Inflammation in Crohn's Disease

NCT05034159
View directory record Official record
Conditions
Crohn Disease, Insomnia, Sleep Disturbance, Pain, Inflammation
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Sep 4, 2026, 3:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy of Center-based Childcare to Mitigate Unhealthy Weight Gain in Preschoolers From Low-income Households During the Summer

NCT07583459
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Childcare
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
3 Years to 5 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Phase 3 Interventional Results available

A Randomized Controlled Trial of Mandatory Naps for Physicians in Training

NCT00874510
View directory record Official record
Conditions
Fatigue
Interventions
Mandatory Naps
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Not applicable Interventional Results available

Neural-net Artificial Pancreas (NAP)

NCT05876273
View directory record Official record
Conditions
Type1 Diabetes
Interventions
Neural-net Artificial Pancreas, University of Virginia Model Predictive Control
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Wrist-worn Device That Produces a Small Vibration on Sleep and Performance That Can Occur During and After Night Shift Work

NCT06665672
View directory record Official record
Conditions
Sleep Duration, Psychomotor Performance
Interventions
Wrist worn vibro-acoustic device
Device
Lead sponsor
Daniel Patterson, PhD, NRP
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 4, 2026, 3:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Sleep Spindles and Memory in Rolandic Epilepsy

NCT04569708
View directory record Official record
Conditions
Rolandic Epilepsy, Rolandic Epilepsy, Benign, Centrotemporal Epilepsy, Centrotemporal; EEG Spikes, Epilepsy of Childhood, Epilepsy; Seizure, Epilepsy
Interventions
Closed loop auditory stimulation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
4 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Chronic Moderate Sleep Restriction in Older Adults

NCT01642719
View directory record Official record
Conditions
Sleep Disturbance, Aging
Interventions
Sleep restriction, Non-sleep restriction
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
4
States / cities
Tucson, Arizona • Los Angeles, California • Brooklyn, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 4, 2026, 3:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Assessment of the Safety and Efficacy of Weighted Wearable Blankets in Healthy Infants During Sleep

NCT06422364
View directory record Official record
Conditions
Sleep
Interventions
Weighted Wearable Blanket provided by Dreamland Baby Co.
Device
Lead sponsor
Indiana University
Other
Eligibility
1 Day to 12 Months
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Not applicable Interventional Results available

Predictors of Response to Insomnia Treatments for Gulf War Veterans

NCT03208049
View directory record Official record
Conditions
Insomnia
Interventions
Behavioral Therapy (BT), Cognitive Therapy (CT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
3
States / cities
Palo Alto, California • Washington D.C., District of Columbia • East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 4, 2026, 3:57 AM EDT
Completed Phase 2 Interventional Results available

A Multicenter Study of NAP (AL-108) in Schizophrenia

NCT00505765
View directory record Official record
Conditions
Schizophrenia
Interventions
AL-108, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
8
States / cities
Los Angeles, California • Catonsville, Maryland • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Sep 4, 2026, 3:57 AM EDT
Terminated Not applicable Interventional Results available

Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease

NCT03256539
View directory record Official record
Conditions
Sleep, Alzheimer Disease, Cognitive Impairment, Aging, CBT
Interventions
Sleep intervention, Placebo intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 4, 2026, 3:57 AM EDT