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ClinicalTrials.gov public records Last synced Sep 22, 2026, 10:31 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Cardiopulmonary Bypass
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Shoulder Pain, Chronic Pain, Musculoskeletal Injury
Interventions
Dry Needling, Sham Dry Needling
Device · Other
Lead sponsor
Army-Baylor University Doctoral Program in Physical Therapy
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Wound Heal
Interventions
Near Infrared Spectroscopy
Diagnostic Test
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Recruiting No phase listed Observational Accepts healthy volunteers

fNIRS for Disorders of Consciousness

NCT07485361
Conditions
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness, Coma, Minimally Conscious State, Unresponsive Wakefulness Syndrome, Brain Injury, TBI Traumatic Brain Injury
Interventions
Functional Near-Infrared Spectroscopy Monitoring
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Blood Pressure
Interventions
NIRS Monitoring
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 6 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

NIRS Monitoring in the NICU and AKI

NCT07222722
Conditions
Acute Kidney Injury (AKI), Postnatal AKI
Interventions
NIRS Monitoring
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
24 Weeks to 30 Weeks
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
- Non-Invasive Near-infrared Spectroscopy (NIRS) device (HEM1 with Foresight Elite Sensor)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Infant, Premature, Diseases, Hypoxia, Necrotizing Enterocolitis
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Up to 3 Weeks
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational

NIRS in Neonatal Cardiac Surgery

NCT00166101
Conditions
Hypoplastic Left Heart, Surgery
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
1 Day to 1 Year
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
Interventions
Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG)
Device
Lead sponsor
Maria Angela Franceschini
Other
Eligibility
0 Hours to 72 Hours
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Phase 2 Interventional

Brain Oxygenation-II

NCT05171881
Conditions
Cerebral Hypoxia
Interventions
Intervention for cerebral hypoxia
Other
Lead sponsor
Valerie Chock, M.D., M.S. Epi
Other
Eligibility
Up to 6 Hours
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
5
States / cities
Loma Linda, California • Palo Alto, California • St Louis, Missouri + 2 more
Completed No phase listed Observational Results available

Cerebral Oxygenation and Autoregulation in Preterm Infants

NCT02147769
Conditions
Intraventricular Hemorrhage of Prematurity, Complications of Prematurity
Interventions
NIRS monitoring
Device
Lead sponsor
Stanford University
Other
Eligibility
Up to 24 Hours
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
7
States / cities
Birmingham, Alabama • Palo Alto, California • San Jose, California + 4 more
Conditions
Anemia
Interventions
Inhaled Nitric Oxide, Placebo
Drug
Lead sponsor
New York Medical College
Other
Eligibility
2 Weeks and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Springfield, Massachusetts • Stony Brook, New York • Valhalla, New York + 1 more
Conditions
Unstable Blood Pressure, Hypotension
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
24 Weeks to 44 Weeks
Enrollment
80 participants
Timeline
2025 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Patent Ductus Arteriosus
Interventions
INVOS Cerebral/Somatic oximeter
Device
Lead sponsor
University of Louisville
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Lousiville, Kentucky
Conditions
Brain Injuries
Interventions
Licox® Brain Tissue Oxygen Monitoring System, Near-infrared spectroscopy (NIRS)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Completed No phase listed Observational

RBC Irradiation, Anemia and Gut Injury

NCT02741648
Conditions
Anemia, Necrotizing Enterocolitis
Interventions
Near Infrared Spectroscopy, Non-invasive Image-based Anemia Assessment
Device · Other
Lead sponsor
Emory University
Other
Eligibility
1 Day to 5 Days
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
3
States / cities
Atlanta, Georgia
Conditions
Depression
Interventions
Transcranial Magnetic Stimulation (TMS), near infrared spectroscopy (NIRS)
Procedure · Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Near-infrared Spectroscopy (NIRS) Neurodevelopmental Outcomes

NCT00464100
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
4 Years to 5 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Major Depression
Interventions
functional Near Infrared Spectroscopy
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
21 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Belmont, Massachusetts
Conditions
Pediatric Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
3 Years to 12 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Cardiac Surgery, Protein Metabolomics, Cerebral Function, Cardiopulmonary Bypass
Interventions
Perioperative and postoperative management
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Infant, Premature, Congenital Heart Disease, Patent Ductus Arteriosus, Necrotizing Enterocolitis
Interventions
Near-infrared spectroscopy (NIRS)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
12 Days to 6 Months
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
3
States / cities
Murray, Utah • Salt Lake City, Utah
Not listed Not applicable Interventional

PDA Occlusion Using NIRS

NCT06359522
Conditions
Organ Perfusion Determined by Using NIRS Post Transcatheter PDA Occlusion or Medical Closure of PDA
Interventions
NIRS monitor
Device
Lead sponsor
University of Louisville
Other
Eligibility
0 Months to 3 Months
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky