- Conditions
- Renal Impairment
- Interventions
- NKTR118 Group1, NKTR118 Group 2, NKTR118 Group3, NKTR118
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011
- U.S. locations
- 3
- States / cities
- Anaheim, California • Orlando, Florida • Overland Park, Kansas
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- Conditions
- Hepatic; Functional Disturbance
- Interventions
- NKTR-118
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
- Interventions
- Naloxegol, Placebo, Laboratory Biomarker Analysis, Quality-of-Life Assessment
- Drug · Other
- Lead sponsor
- Alliance for Clinical Trials in Oncology
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 660
- States / cities
- Anchorage, Alaska • Fairbanks, Alaska • Kingman, Arizona + 407 more
- Conditions
- Constipation
- Interventions
- MOVANTIK™ (naloxegol), Sugar Pill
- Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Opioid Induced Constipation
- Interventions
- Polyethylene Glycol 3350, Movantik
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 84 Years
- Enrollment
- 276 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 53
- States / cities
- Huntsville, Alabama • Phoenix, Arizona • Anaheim, California + 46 more