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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:34 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 279 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: NRT patches Clear all

Conditions: Smoking Cessation, Obesity
Interventions: Self-Regulation strategies + large changes (SR), Healthy Lifestyle Education (LE), Smoking Cessation Treatment; Behavioral · Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Nicotine Dependence, Opiate Dependence
Interventions: Intensive, tailored intervention, NJ Quitline Referral; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Tobacco Dependence
Interventions: C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker, Lung Cancer Screening; Behavioral · Drug · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 50 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Smoking Cessation
Interventions: Non-invasive vagus nerve stimulator plus nicotine replacement patches, nicotine replacement patches; Combination Product · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cigarette Smoking, Tobacco Smoking, Smoking, Tobacco
Interventions: nicotine patch plus nicotine gum/lozenge, Intensive Alcohol Intervention; Drug · Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 75 Years
Enrollment: 352 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tobacco Use Disorder, Schizophrenia
Interventions: sensorimotor replacement, 42 mg transdermal nicotine replacement, Placebo transdermal nicotine, usual brand smoking; Behavioral · Drug · Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking Cessation, Smoking, Nicotine Dependence
Interventions: Varenicline, Nicotine lozenge, Nicotine Patch; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 1,086 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 2
States / cities: Madison, Wisconsin • Milwaukee, Wisconsin

Conditions: Smoking, Nicotine Dependence, Mental Disorders
Interventions: Cognitive / Motivational Individual Sessions, Attention Control Individual Sessions, Nicotine Patch, Group Curriculum; Behavioral · Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Smoking Cessation Counselling
Interventions: Free Help, Free Nicotine message, Spanish: Free help message, Spanish: Free nicotine message; Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 4,171 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Coronary Artery Disease, Smoking Cessation
Interventions: genotype-guided therapy, Nicotine patch, Smoking cessation counseling; Other · Drug · Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Smoking, Smoking Cessation
Interventions: Nicotine Replacement Product; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Smoking, Pulmonary Disease, Chronic Obstructive, Tobacco Use Disorder
Interventions: Standard Smoking Cessation, Extended Nicotine Replacement Therapy, Nicotine replacement therapy; Other · Drug
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 398 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Nicotine Dependence
Interventions: Bupropion SR, Nicotine Patch, Placebo Patch and Placebo Pill; Drug
Lead sponsor: Southern Illinois University Carbondale; Other
Eligibility: 18 Years to 55 Years
Enrollment: 197 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 1
States / cities: Carbondale, Illinois

Conditions: Cigarette Smoker, Tobacco Use Disorder
Interventions: Nicotine Lozenge, Nicotine Patch, Placebo, Tobacco Cessation Counseling, Varenicline; Drug · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 631 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation, Cervical Cancer, High Grade Cervical Dysplasia
Interventions: Smoking Cessation treatment delivered by Tobacco Free Florida Quitline, Nicotine patch, Nicotine Lozenge, Motivation and Problem Solving (MAPS) intervention; Behavioral · Drug
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Smoking Cessation, HIV Infections
Interventions: Sessions with a trained counselor, Cell phone messages, Offered nicotine replacement therapy, Self-help guide for quitting smoking; Behavioral · Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Nicotine Dependence
Interventions: Nicoderm CQ transdermal nicotine, placebo; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 45 Years
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Tobacco Smoking
Interventions: Tailored behavioral counseling, Standard of Care; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Smoking Cessation, Alcohol Drinking
Interventions: Nicotine Replacement Therapy, Bupropion, Cognitive Behavioral Treatment, Mobile Contingency Management, Mobile Monitoring; Other · Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking Cessation
Interventions: hypnotherapy, Nicotine; Behavioral · Drug
Lead sponsor: North Shore Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Salem, Massachusetts

Conditions: Smoking Cessation
Interventions: Treatment As Usual (TAU), Nicotine Replacement Therapies, Text Message Intervention (TMI); Other · Drug · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 203 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Alcoholism, Smoking
Interventions: naltrexone (Revia), nicotine replacement patch; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 50 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2003
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation
Interventions: Counseling, combination NRT; Behavioral · Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Smoking Cessation
Interventions: nicotine polacrilex, nicotine transdermal system, nicotine inhaler; Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Omaha, Nebraska

Search by objective public record fields.

A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers

Developing a Smoking Cessation Intervention for Methadone Maintained Smokers

C-Raven, a Virtual Tobacco Cessation Intervention in the Community

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

Enhancing Smoking Cessation in the Homeless Population

Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia

A Comparative Effectiveness & Long Term Health Study in Wisconsin Smokers

Helping Those With Mental Illness Quit Smoking

Pragmatic Trial of Text Messages to Recruit Unassisted Tobacco Users Into Quitline Service

PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo

Treating Caregivers Who Smoke at AFCH

Smoking Cessation Versus Long-term Nicotine Replacement Among High-risk Smokers

Nicotine Replacement Therapy (NRT) and Bupropion Mechanisms of Effectiveness in Smokers

Varenicline and Combined NRT for Smoking Cessation

Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS)

Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV

Assessment of High Dose Transdermal Nicotine for Fast Metabolizers of Nicotine

Development of a Tailored Smoking Cessation Program for Individuals With HIV Infection in Washington, D.C.

Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking

Smoking Cessation After Hospitalization for a Cardiopulmonary Illness

A Pilot Text Messaging Intervention to Reduce Smoking in Office-based Buprenorphine and Inpatient Detoxification Patients

Behavioral/Drug Therapy for Alcohol-Nicotine Dependence (Naltrexone/Nicotine Patch)

Nicotine Replacement Therapy (NRT) Sampling and Selection to Increase Medication Adherence

Analysis of Aldehyde Biomarkers of Exposure and Host Response