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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:03 PM EST

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Showing 73–96 of 279 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: NRT patches Clear all

Conditions: Smoking Cessation
Interventions: Motivational Interviewing (MI), Nicotine Replacement Therapy (NRT), Nicotine Lozenge, Message Framing, saliva sample; Behavioral · Drug · Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 50 Years to 80 Years
Enrollment: 807 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2027
U.S. locations: 18
States / cities: Los Angeles, California • Walnut Creek, California • La Grange, Georgia + 14 more

Conditions: Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions: Brief Intervention with NRT Initiation; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking
Interventions: Brief tobacco counseling; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 2,637 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 3
States / cities: Jackson, Mississippi • New York, New York • Eugene, Oregon

Conditions: Tobacco Use Cessation
Interventions: VergeRx, SmokefreeTXT, NRT Lozenge (Combination), Extended NRT Patch (16 weeks), Standard NRT Patch (8 weeks); Behavioral · Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 592 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2032
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Newly Diagnosed Cancer Patients
Interventions: Hospital Counseling + Nicotine Replacement Therapy. questionaires, Hospital Counseling + Nicotine Replacement + Presurgical Scheduled Reduced Smoking, questionaires; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Cigarette Smoker, Tobacco Use Disorder
Interventions: Behavioral Intervention, Laboratory Biomarker Analysis, Nicotine Patch, Questionnaire Administration, Smoking Cessation Intervention; Behavioral · Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation
Interventions: Nicotine transdermal patch; Drug
Lead sponsor: University of Texas at Austin; Other
Eligibility: 23 Years to 60 Years · Male only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Endothelial Dysfunction
Interventions: Nicotine Replacement Therapy (NRT), Gamma-Tocopherol, Placebo, Smoking cessation; Other · Dietary Supplement · Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 60 Years
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Tobacco Smoking
Interventions: Motivational Interviewing, Nicotine Replacement Therapy Sampling, Referral Only; Behavioral · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 65 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Smoking Cessation
Interventions: WEB, Social Network, Nicotine Replacement Therapy (NRT); Behavioral
Lead sponsor: Truth Initiative; Other
Eligibility: 18 Years and older
Enrollment: 5,292 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Lung Cancer
Interventions: smoking cessation intervention, bupropion hydrochloride, nicotine, psychosocial assessment and care; Behavioral · Drug · Procedure
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2004
U.S. locations: 175
States / cities: Anniston, Alabama • Mobile, Alabama • Phoenix, Arizona + 115 more

Conditions: Tobacco Use Disorder
Interventions: ModafinilNicotine Replacement Therapy, Modafinil; Drug
Lead sponsor: Catherine Martin, MD; Other
Eligibility: 16 Years to 40 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Nicotine Dependence
Interventions: nicotine patch (Nicoderm Committed Quitter (CQ), Habitrol), denicotinized cigarettes (Quest 3 cigarettes); Drug · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 60 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cigarette Smoking
Interventions: D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure, Progressive Muscle Relaxation, Placebo; Drug · Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 21 Years to 55 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Use
Interventions: EX program; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years to 120 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Smoking, Pain, Smoking Cessation
Interventions: PASS2, Treatment as Usual; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Tobacco Use Cessation, Cancer Prevention
Interventions: Nicotine Patch, Questionnaires, Carbon Monoxide (CO) Test, Health Education and Handouts, Culturally Tailored Reading Materials, Counseling Sessions; Drug · Behavioral · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cigarette Smoking, Smoking Cessation
Interventions: Contingency Management (CM), Transdermal nicotine skin patches (i.e. Habitrol), Supportive Counseling; Behavioral · Drug · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking, Smoking Cessation, Smoking, Tobacco, Opioid Use, Opioid Abuse
Interventions: Nicotine patch; Drug
Lead sponsor: University of Houston; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation
Interventions: Android Wear smartwatch, Adaptive Treatment, Nicotine Patch, interviewing-based counseling; Behavioral · Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation, Mental Illness
Interventions: Smart-T Mental Health+ and NRT, QuitGuide + NRT; Combination Product
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 100 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Smoking Cessation
Interventions: Nicotine patch, in-person counseling and quitline counseling, Preparation Nicotine Mini-Lozenges, Combination NRT (nicotine patch + nicotine mini-lozenges), Intensive In-Person Cessation Counseling, Extended Maintenance Counseling Calls, Automated Adherence Calls; Drug · Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 623 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Tobacco Use Disorder
Interventions: Very low nicotine content (VLNC) cigarettes and nicotine replacement therapy (NRT), Reduce cigarettes per day (CPD) with nicotine replacement therapy (NRT); Other
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Tobacco Use Disorder
Interventions: active repetitive transcranial magnetic stimulation, sham repetitive transcranial magnetic stimulation, cognitive behavioral therapy for smoking cessation, nicotine replacement therapy; Device · Behavioral · Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Search by objective public record fields.

Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

Treating Low-Income Smokers in the Hospital Emergency Department

Tobacco Cessation Via Public Health Dental Clinics

VergeRx for Smokers Not Ready to Quit

Smoking Cessation Intervention for Cancer Patients

Behavioral Activation Therapy and Nicotine Replacement Therapy in Increasing Smoking Cessation

Smoking Cessation and Sexual Health in Men

Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function

Tobacco and Socioeconomic Disadvantage

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery

Safety of Combining Modafinil and Nicotine Replacement Therapy in Treating Nicotine Dependent Adolescents

Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes

Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers

Be A Quitter: Illinois Small Business EX Program Dissemination

Pain and Smoking Study 2.0: A Randomized Clinical Trial of Smoking Cessation Among Veterans With Chronic Pain

Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers

Contingency Management, Quitting Smoking, and ADHD

Opioids and Smoking Cessation

Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation

Mobile App for Smoking Cessation and Mental Health

A Comparative Effectiveness RCT of Optimized Cessation Treatments

Switching to Very Low Nicotine Content Cigarettes vs Reducing Cigarettes Per Day

Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD