Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:27 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 279 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: NRT patches Clear all

Conditions: Drug Addiction, Smoking Cessation
Interventions: Nicotine transdermal system, Nicotine containing cigarette, Placebo cigarette; Drug · Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking
Interventions: CBME, Optional NRT; Behavioral · Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 14 Years to 21 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Tobacco Cessation, Peripheral Artery Disease
Interventions: Tobacco Treatment Research Program Standard Care; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 100 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Smoking Cessation, Tobacco Use Disorder
Interventions: Nicotine Replacement Therapies, Nicotine patch, Folic Acid; Drug · Dietary Supplement
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 13 Years to 18 Years
Enrollment: 128 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2004
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: HIV, AIDS, Smoking Cessation
Interventions: Algorithm Treatment, Quitline only; Drug · Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 371 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Smoking Cessation
Interventions: Nicotine Patch, Telephone Counseling, Placebo, Self-Help Materials; Drug · Behavioral · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 4,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: San Diego, California

Conditions: Smoking Cessation
Interventions: Telephone counseling, Nicotine patches, Incentive; Behavioral · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 3,816 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: San Diego, California

Conditions: Current Smoker, Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Nasopharyngeal Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
Interventions: Bupropion Hydrochloride, Laboratory Biomarker Analysis, Nicotine Replacement, Quality-of-Life Assessment, Questionnaire Administration, Varenicline; Drug · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Winston-Salem, North Carolina • Charleston, South Carolina

Conditions: Tobacco Use Disorder
Interventions: Cognitive Behavioral Therapy for Smoking Cessation, Nicotine Replacement Therapy, Bupropion, Varenicline, Mobile Contingency Management, Clinic-Based Smoking Cessation Counseling; Behavioral · Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smokeless Tobacco, Nicotine Dependence
Interventions: Tailored behavioral intervention, Behavioral activation for elevated depressive symptoms, Post-cessation weight gain management, Alcohol use risk reduction, Nicotine replacement therapy - transdermal nicotine patch, Nicotine replacement therapy - nicotine lozenge, Nicotine replacement therapy - nicotine gum, Bupropion sustained release, Varenicline, Combination nicotine replacement therapy, Combination nicotine replacement therapy + bupropion, Tobacco quit line, Educational materials; Behavioral · Drug
Lead sponsor: Mark Vander Weg; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 123 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Tobacco Smoking
Interventions: Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback, Nicotine patch; Behavioral · Biological · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 21 Years to 50 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Smoking Cessation
Interventions: Nicotine Replacement Therapy, Smoking Cessation Counseling; Drug · Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 278 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Kansas City, Kansas • Kansas City, Missouri

Conditions: Nicotine Dependence
Interventions: Nicotine patch - transdermal, placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 60 Years
Enrollment: 127 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Nicotine Replacement, Questionnaire Administration, Vaping; Drug · Other · Device
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 1,500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Limited Stage Small Cell Lung Cancer, Recurrent Small Cell Lung Cancer, Stage IA Non-small Cell Lung Cancer, Stage IB Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Tobacco Use Disorder
Interventions: questionnaire administration, quality-of-life assessment, counseling intervention, internet-based intervention, telephone-based intervention, educational intervention, nicotine replacement therapy; Other · Procedure · Behavioral + 1 more
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Tobacco Use Cessation
Interventions: Nicotine patch, nicotine gum, nicotine nasal spray, nicotine inhaler, Varenicline or bupropion, Contingency Management; Drug · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 323 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 4
States / cities: Bridgeport, Connecticut • New Haven, Connecticut • Brooklyn, New York + 1 more

Conditions: Smoking, Tobacco
Interventions: Counseling, Nicotine patch, Community Resource; Behavioral · Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 50 Years to 80 Years
Enrollment: 642 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 6
States / cities: Boston, Massachusetts • Newton, Massachusetts • Oak Bluffs, Massachusetts + 1 more

Conditions: Smoking Cessation, Nicotine Dependence, Tobacco Use, Cigarette Smoking
Interventions: Social media-based education, counseling, and support, Nicotine replacement therapies (NRT), Gamification; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Smoking
Interventions: transdermal nicotine replacement therapy; Drug
Lead sponsor: Duke University; Other
Eligibility: 21 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Smoking
Interventions: Nicotine Patch, E-cigarette; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 65 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Tobacco-Use Disorder, Schizophrenia, Psychotic Disorders
Interventions: bupropion SR, Cognitive Behavioral Group Therapy, nicotine replacement therapy; Drug · Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1998 – 2004
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Smoking Cessation, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette, Smoking (Tobacco) Addiction
Interventions: ACT Lung Health Intervention; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 18 Years to 100 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Smoking, Veterans
Interventions: Nicotine gum, mobile contingency management, Telephone counseling, Nicotine patch, Nicotine lozenge, Smart phone, Carbon monoxide monitor; Other · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 291 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cigarette Smoking, Nicotine Dependence
Interventions: varenicline (Chantix), bupropion (Zyban), nicotine patches; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: Durham, North Carolina • Raleigh, North Carolina

Search by objective public record fields.

Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3

Youth Smoking Cessation: Therapy +/- "The Patch"

Onsite Tobacco Cessation Treatment for Patients With PAD

Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1

Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care

Telephone Counseling and the Distribution of Nicotine Patches to Smokers

A Randomized Trial of Medi-Cal Beneficiaries Calling the California Smokers' Helpline

Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness

Treating Smokeless Tobacco Use in Rural Veterans

Heart Rate Variability Biofeedback for Smoking Cessation Treatment

Informing Tobacco Treatment Guidelines for African American Non-Daily Smokers

Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging

A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior

Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancer

A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV

Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)

Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment

Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and the Environment

E-cigarettes to Promote Smoking Reduction Among Individuals With Schizophrenia

Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke

ACT Lung Health Intervention: Phase Two

Mobile Contingency Management for Smoking Cessation in Returning US Veterans

Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants