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Showing 1–4 of 4 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Results available

Long-Term Study of Nitisinone to Treat Alkaptonuria

NCT00107783
Conditions
Alkaptonuria
Interventions
Nitisinone (NTBC)
Drug
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
30 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional

Study of NTBC for Tyrosinemia I

NCT00004443
Conditions
Tyrosinemia I
Interventions
NTBC
Drug
Lead sponsor
University of Washington
Other
Eligibility
Up to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2006
U.S. locations
2
States / cities
Portland, Oregon • Seattle, Washington
Completed Not applicable Interventional

Prevention of Dichloroacetate Toxicity

NCT00031161
Conditions
Acidosis, Lactic, Chronic Disease
Interventions
Nitisinone (NTBC), Dichloroacetate, Low-tyrosin diet
Drug · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
3 Months to 21 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Alkaptonuria
Interventions
Nitisinone
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
La Jolla, California