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Conditions: Post Traumatic Stress Disorder
Interventions: Narrative Exposure Therapy; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: Prolonged Exposure (PE); Behavioral
Lead sponsor: Research Foundation for Mental Hygiene, Inc.; Other
Eligibility: 18 Years to 60 Years
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Trauma, Psychological, Trauma and Stressor Related Disorders
Interventions: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), School-Adapted TF-CBT (S-TF); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 7 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: PTSD
Interventions: trauma-focused treatment; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 3
States / cities: Boston, Massachusetts • Charleston, South Carolina • Madison, Wisconsin

Conditions: Post Traumatic Stress Disorder
Interventions: Narrative Exposure Therapy; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Posttraumatic Stress Disorder, PTSD
Interventions: Trauma Affect Regulation: Guide for Education and Therapy, Present Centered Therapy (PCT) - psychotherapy, No-treatment "waitlist" group; Behavioral · Other
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 147 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 2
States / cities: Farmington, Connecticut • Hartford, Connecticut

Conditions: Suicide, Attempted, Suicide Threat
Interventions: WET-SP, TAU; Behavioral
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder, Stress, Burn Out, Mental Health Issue
Interventions: Start with the Heart Students, Start with the Heart Teachers, Cue Centered Therapy Counselors, Cue Centered Therapy Students, iSWAB-DNA; Behavioral · Genetic
Lead sponsor: Stanford University; Other
Eligibility: 11 Years to 17 Years
Enrollment: 80,800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Post-Traumatic Stress Disorder
Interventions: Written Disclosure; Other
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Suicide, Posttraumatic Stress Disorder
Interventions: Written Exposure Therapy -for Suicide, Treatment as Usual; Behavioral
Lead sponsor: Boston VA Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Fort Hood, Texas

Conditions: Trauma, Posttraumatic Stress Disorder
Interventions: Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT); Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 7 Years to 14 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Post Traumatic Stress Disorder
Interventions: Written Exposure Therapy, repetitive transcranial magnetic stimulation; Behavioral · Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 60 Years
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Temple, Texas

Conditions: Anxiety, Mild Cognitive Impairment, Alzheimer Disease, Dementia
Interventions: Computerized Anxiety Sensitivity Treatment, Health Education Control; Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 60 Years and older
Enrollment: 388 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 3
States / cities: Tallahassee, Florida • Athens, Ohio • Columbus, Ohio

Conditions: Post-traumatic Stress Disorder, Moral Injury
Interventions: Medical Music, Narrative Writing, Prolonged Exposure Therapy, Interpersonal Psychotherapy; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: PTSD
Interventions: Written Exposure Therapy (WET); Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 720 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 10
States / cities: Albion, New York • Brooklyn, New York • Corfu, New York + 3 more

Conditions: Posttraumatic Stress Disorder, Depressive Symptoms, Burn Out, Anxiety, Work Related Stress
Interventions: WET; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Posttraumatic Stress Disorder
Interventions: Trauma-Focused Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Delaware Division of Prevention and Behavioral Health Services; Government
Eligibility: 7 Years to 17 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Wilmington, Delaware

Conditions: Insomnia, PTSD - Post Traumatic Stress Disorder, Nightmares
Interventions: Cognitive-Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Written Exposure Therapy (WET), Sleep Hygiene; Behavioral
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 18 Years to 65 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Kileen, Texas

Conditions: Substance Use Disorders, Posttraumatic Stress Disorder
Interventions: Written Exposure Therapy, Neutral Topic Writing; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Psychological Trauma, Trauma and Stress Related Disorders, Substance-Related Disorders, Substance Use, Substance Use Disorders
Interventions: Immediate Narrative Exposure Therapy (NET)+, Waitlist + NET+; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: Written Exposure Therapy, Trauma-focused Cognitive Behavior Therapy; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 18 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
Interventions: Creating Change (CC), Seeking Safety (SS); Behavioral
Lead sponsor: VA Boston Healthcare System; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Posttraumatic Stress Disorder
Interventions: Stepped Care TF-CBT, Standard TF-CBT; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 3 Years to 7 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Post Traumatic Stress Disorder
Interventions: Written Exposure Therapy (WISE), Non-emotional Writing; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 6
States / cities: Gainesville, Florida • Indianapolis, Indiana • Worcester, Massachusetts + 3 more

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Adaptation and Randomized Controlled Trial of Written Exposure Therapy for Adolescents

Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder

Stepped Care for Young Children After Trauma

Written Exposure Therapy to Improve Lives After Stress Exposure