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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:29 PM EDT

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Showing 1–24 of 136 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Near Infrared Light Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy

NCT03716167
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
Summus Laser, Summus Laser Sham
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Longitudinal Spatial Frequency Domain Imaging Study

NCT05672992
View directory record Official record
Conditions
Systemic Scleroderma
Interventions
Spatial-frequency domain imaging (SFDI)
Other
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Not listed No phase listed Observational

Non Contact Measurement of Vital Signs

NCT02287220
View directory record Official record
Conditions
Hypoxemia, Hypoxia
Interventions
Non-Contact Oximetry
Device
Lead sponsor
University of Virginia
Other
Eligibility
Up to 12 Months
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 21, 2026, 5:29 PM EDT
Recruiting Not applicable Interventional

Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33

NCT05573074
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Transcranial Photobiomodulator, Sham
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York • Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lipiflow vs iLux Patient Acceptance and Comfort Study

NCT04454983
View directory record Official record
Conditions
Meibomian Gland Dysfunction, Dry Eye
Interventions
Lipiflow Thermal Pulsation System, iLux System
Device
Lead sponsor
Epstein, Arthur B., OD, FAAO
Individual
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Early Phase 1 Interventional

Photobiomodulation for the Treatment of Diabetic Macular Edema

NCT02457975
View directory record Official record
Conditions
Diabetic Retinopathy
Interventions
670nm PBM, intravitreous VEGF-inhibitors
Device · Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Phase 3 Interventional Results available

A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery

NCT05754333
View directory record Official record
Conditions
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
Interventions
pudexacianinium chloride
Drug
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
12 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
6
States / cities
Orlando, Florida • Tampa, Florida • Weston, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 21, 2026, 5:29 PM EDT
Withdrawn Not applicable Interventional

LED Light Therapy to Improve Cognitive & Psychosocial Function in TBI-PTSD Veterans

NCT02356861
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Post-traumatic Stress Disorder (PTSD)
Interventions
Photomedex Sham Helmet with Red/Near-Infrared Light-Emitting Diodes (LEDs) that are not turned on
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 21, 2026, 5:29 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury

NCT02990078
View directory record Official record
Conditions
TBI
Interventions
Sildenafil citrate, Functional Near Infared Spectroscopy, Hypercapnia Challenge
Drug · Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional Results available

Child Characteristics, Neuromarkers, and Intervention Components Impacting Treatment Outcome: CCT, TF-CBT, TAU

NCT02926677
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cue-Centered Treatment (CCT), Trauma-Focused CBT (TF-CBT), Treatment as Usual, NIRScout
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years to 18 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Sacramento, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Combined Red and Near Infrared Light-emitting Diode (LED) Therapy on Tissue Regeneration Post Laser Treatment

NCT04834817
View directory record Official record
Conditions
Wound Heal
Interventions
Celluma POD
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional Results available

Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression

NCT04366258
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Transcranial Photobiomodulator, Sham
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
Charlestown, Massachusetts • New York, New York • Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 21, 2026, 5:29 PM EDT
Active, not recruiting Phase 1 Interventional

Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship

NCT05937269
View directory record Official record
Conditions
Lymphedema of Face, Head and Neck Cancer
Interventions
Near-infrared fluorescence lymphatic imaging, advanced pneumatic compression therapy
Combination Product · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional Results available

Photobiomodulation in Autism Spectrum Disorder (ASD)

NCT03724552
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Transcranial LED Therapy (Participants ages 9-17), Transcranial LED Therapy (Participants ages 18-59)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
9 Years to 59 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Oct 21, 2026, 5:29 PM EDT
Recruiting Not applicable Interventional

Autism Research Project With Non-Invasive Near-Infrared Light Stimulation

NCT06203938
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Transcranial infrared light stimulation, Sham
Device
Lead sponsor
Francisco Gonzalez-Lima, PhD
Other
Eligibility
4 Years to 60 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures

NCT01693484
View directory record Official record
Conditions
Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
Interventions
ICG (Indocyanine Green)
Drug
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Phase 3 Interventional

IS-001 Injection in Patients Undergoing Robotic-Assisted Gynecological Surgery

NCT05954767
View directory record Official record
Conditions
Ureter Injury
Interventions
IS-001
Drug
Lead sponsor
Intuitive Surgical
Industry
Eligibility
16 Years to 75 Years · Female only
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Newport Beach, California • Miami, Florida • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Phase 1 Interventional

A Single Dose, Open-Label, Dose-escalation Study of the Safety and Imaging Characteristics of LS301-IT for Intraoperative Imaging of Lung Cancer

NCT06713564
View directory record Official record
Conditions
Lung Cancers
Interventions
LS301-IT
Drug
Lead sponsor
Integro Theranostics
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Terminated Not applicable Interventional

Transcranial Pulse Near-Infrared Light in Generalized Anxiety Disorder: a Placebo-Controlled Study

NCT03420456
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Noise Exposure and Near-Infrared Light

NCT03834714
View directory record Official record
Conditions
Hearing Loss, Noise-Induced
Interventions
Near Infrared Light, Noise Stimulus, Sham Near Infrared Light
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 45 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Fort Rucker, Alabama • Miami, Florida • Wright-Patterson Air Force Base, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional

Subscapularis Indocyanine Green Perfusion Pilot Study

NCT05179941
View directory record Official record
Conditions
Shoulder Pain, Shoulder Arthritis, Shoulder Arthroplasty
Interventions
Perfusion with Indocyanine green
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 4, 2023 · Synced Oct 21, 2026, 5:29 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Diffuse Cutaneous Scleroderma (DSSc) SFDI Study

NCT07090226
View directory record Official record
Conditions
Systemic Scleroderma, Diffuse Cutaneous Scleroderma
Interventions
Spatial-frequency domain imaging (SFDI)
Other
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transcranial Near-Infrared Light in Healthy Subjects: a Cerebral Blood Flow Study With Diffuse Correlation Spectroscopy

NCT03740152
View directory record Official record
Conditions
Cognitive Change
Interventions
Transcranial Light Therapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 21, 2026, 5:29 PM EDT
Completed Not applicable Interventional

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

NCT05550948
View directory record Official record
Conditions
ALL, Hodgkin Lymphoma, Cancer, Survivorship
Interventions
Transcranial photobiomodulation (tPBM) - Mobile System
Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 21, 2026, 5:29 PM EDT