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ClinicalTrials.gov public records Last synced Oct 2, 2026, 1:04 PM EDT

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Showing 25–48 of 215 matching trials from the live ClinicalTrials.gov search.
Conditions
Anemia
Interventions
Inhaled Nitric Oxide, Placebo
Drug
Lead sponsor
New York Medical College
Other
Eligibility
2 Weeks and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Springfield, Massachusetts • Stony Brook, New York • Valhalla, New York + 1 more
Conditions
Epilepsies, Partial
Interventions
Near-infrared spectroscopy
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
7 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic, Cerebral Hemorrhage, Ischemic Stroke, Delayed Emergence From Anesthesia, Encephalopathy
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Dallas, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

NCT06725550
Conditions
Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing, Magnetic Resonance Imaging, Circulating Biomarkers, Electroencephalography, Functional Near-infrared Spectroscopy
Interventions
needling acupuncture, laser acupuncture
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
14 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Cincinnati, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

NCT07044596
Conditions
Mild Traumatic Brain Injury, Post Concussion Syndrome
Interventions
Functional near-infrared spectroscopy (fNIRS), V1 stimulation electrodes, Magnetic Resonance Imaging (MRI), MAGNUS scanner
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
20 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Local Muscular Endurance and Fatigue, NIRS Skeletal Muscle Mitochondrial Capacity, Acute Taurine Supplementation
Interventions
Acute Taurine Supplementation, Acute Placebo Supplementation
Dietary Supplement
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 40 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Pain
Interventions
fNIRS
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Month to 16 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed No phase listed Observational Results available

NIRS Monitoring to Detect AKI in Preterm Infants

NCT03384173
Conditions
Acute Kidney Injury, Premature Infant
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
1 Minute to 7 Days
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Acute Scrotum, Testicular Torsion
Interventions
Hutchison Technologies Inspectra StO2 SpotCheck Near-Infrared Spectroscopy
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
1 Month to 21 Years · Male only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Depression, Major Depressive Disorder
Interventions
fNIRS measurement
Other
Lead sponsor
Kernel
Industry
Eligibility
18 Years to 75 Years
Enrollment
540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
10
States / cities
Costa Mesa, California • La Jolla, California • Los Angeles, California + 4 more
Conditions
Neonatal Encephalopathy
Interventions
Transcutaneous Carbon Dioxide Monitoring
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
0 Days to 3 Days
Enrollment
53 participants
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Wound Heal
Interventions
Near Infrared Spectroscopy
Diagnostic Test
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
Interventions
Personalized Transcranial Direct Current Stimulation (tDCS), Active-Sham
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years to 90 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Terminated No phase listed Observational Accepts healthy volunteers

Near Infrared Spectroscopy in Children With Autism and ADHD

NCT01730079
Conditions
Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, Autism, Autism Spectrum Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
4 Years to 8 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Hemoglobin, Cerebral Oxygenation, Congenital Heart Disease
Interventions
Noninvasive hemoglobin monitoring
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Days to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Chronic Pain Syndrome, Opioid Use
Interventions
Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Traumatic Brain Injury, Mild Traumatic Brain Injury, Post-Concussion Syndrome
Interventions
Sildenafil Citrate
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

NIRS for the Diagnosis of Myofascial Pelvic Pain

NCT07181447
Conditions
Myofascial Pelvic Pain
Interventions
Pelvic Floor Muscle Assessment by Near-Infrared Spectroscopy
Diagnostic Test
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults

NCT06995560
Conditions
Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition, Psychomotor Performance, Neurophysiology
Interventions
Active Transcranial Electrical Stimulation, Sham Transcranial Electrical Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity

NCT01283451
Conditions
Acute Compartment Syndrome
Interventions
Muscle contraction
Behavioral
Lead sponsor
J&M Shuler
Industry
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Vascular Disease, Peripheral, Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions
Not listed
Lead sponsor
MIMOSA Diagnostics Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2025
U.S. locations
1
States / cities
Lake Success, New York
Conditions
Anesthesia
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 6 Months
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D and Muscle Metabolic Function

NCT02221596
Conditions
Healthy
Interventions
vitamin D, aerobic training
Dietary Supplement · Other
Lead sponsor
David Travis Thomas
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Depression
Interventions
Transcranial Magnetic Stimulation (TMS), near infrared spectroscopy (NIRS)
Procedure · Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts