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ClinicalTrials.gov public records Last synced Sep 13, 2026, 4:28 PM EDT

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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Near-Infrared Spectroscopy (NIRS) Sensor Clear all
Withdrawn Not applicable Interventional

Intraoperative Goal-directed Fluid Management

NCT00554944
View directory record Official record
Conditions
Obesity, Abdominal Surgery, Hysterectomy, Genital Prolapse
Interventions
Esophageal probe
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 22, 2017 · Synced Sep 13, 2026, 4:28 PM EDT
Completed Not applicable Interventional

Assessing the Feasibility of a Novel Non-Invasive Sensor for Guiding Wounded Warrior Rehabilitation

NCT02887755
View directory record Official record
Conditions
Rehabilitation Post-amputation
Interventions
Near-Infrared Spectroscopy (NIRS) Sensor
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 1, 2018 · Synced Sep 13, 2026, 4:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of Near Infrared Spectroscopy to Detect Muscle Perfusion in the Lower Extremity of Uninjured Subjects

NCT01284023
View directory record Official record
Conditions
Acute Compartment Syndrome
Interventions
Shaving
Other
Lead sponsor
J&M Shuler
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 13, 2026, 4:28 PM EDT
Completed No phase listed Observational

Near-infrared Spectroscopy (NIRS) for Intracranial Hematoma Detection in Children

NCT02149082
View directory record Official record
Conditions
Intracranial Hematoma
Interventions
Infrascanner Model 2000
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 18 Years
Enrollment
465 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Sep 13, 2026, 4:28 PM EDT
Not yet recruiting No phase listed Observational

Continuous Assessment of Brain Blood Perfusion in Subarachnoid Hemorrhage Patients Using Near-Infrared Spectroscopy (NIRS)

NCT06932640
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
- Non-Invasive Near-infrared Spectroscopy (NIRS) device (HEM1 with Foresight Elite Sensor)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 13, 2026, 4:28 PM EDT
Completed No phase listed Observational

NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery

NCT01849120
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
EQUANOX Advance 8004CB sensor
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
Up to 3 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Sep 13, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NIRS Monitoring in the NICU and AKI

NCT07222722
View directory record Official record
Conditions
Acute Kidney Injury (AKI), Postnatal AKI
Interventions
NIRS Monitoring
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
24 Weeks to 30 Weeks
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 13, 2026, 4:28 PM EDT
Not listed No phase listed Observational

Brain Activity During Gait in Parkinson's

NCT04863560
View directory record Official record
Conditions
Parkinson Disease
Interventions
Auditory Cueing, Visual Cueing, tactile Cueing
Other
Lead sponsor
Northumbria University
Other
Eligibility
50 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Sep 13, 2026, 4:28 PM EDT
Not listed No phase listed Observational

Evaluating the Diagnostic Performance of ACS Using NIRS in Traumatized Lower Extremities

NCT03604029
View directory record Official record
Conditions
Compartment Syndrome of Leg
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 8, 2020 · Synced Sep 13, 2026, 4:28 PM EDT
Terminated Not applicable Interventional Results available

Validation of Mixed Venous Blood Oxygen Saturation Obtained With a Novel Mathematical Equation

NCT00783952
View directory record Official record
Conditions
Mixed Venous Oxygen Saturation, Tissue Oxygenation
Interventions
Cerebral/Somatic Tissue Oximeter device, Pulmonary artery catheter
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Sep 13, 2026, 4:28 PM EDT
Completed No phase listed Observational Results available

NIRS Monitoring to Detect AKI in Preterm Infants

NCT03384173
View directory record Official record
Conditions
Acute Kidney Injury, Premature Infant
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
1 Minute to 7 Days
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Sep 13, 2026, 4:28 PM EDT
Not yet recruiting No phase listed Observational

Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics

NCT07706140
View directory record Official record
Conditions
Hemoglobin, Cerebral Oxygenation, Congenital Heart Disease
Interventions
Noninvasive hemoglobin monitoring
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Days to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 13, 2026, 4:28 PM EDT
Terminated Not applicable Interventional

Feasibility of a Non-invasive, Trans-abdominal, Low Cost Fetal Oximetry Probe on Pregnant Human Subjects

NCT03013842
View directory record Official record
Conditions
Pregnancy, Abdominal
Interventions
Raydiant Oximetry Sensor System
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Sep 13, 2026, 4:28 PM EDT
Withdrawn No phase listed Observational

The Newborn Project: Examining the Oxygenation of Brain Tissue During General Anesthesia

NCT03057587
View directory record Official record
Conditions
Blood Pressure
Interventions
NIRS Monitoring
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 6 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Sep 13, 2026, 4:28 PM EDT
Withdrawn No phase listed Observational

Brain, Gut and Kidney Blood Flow During Medical Closure of PDA

NCT00554307
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
INVOS Cerebral/Somatic oximeter
Device
Lead sponsor
University of Louisville
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Lousiville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Sep 13, 2026, 4:28 PM EDT
Completed No phase listed Observational

Reliability of Sensor Spacing for NIRS in Traumatic Tibia Fractures

NCT02301832
View directory record Official record
Conditions
Orthopedic Disorders, Tibial Fractures
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 13, 2026, 4:28 PM EDT
Completed Not applicable Interventional Results available

Use of NIRS in Preterm Population Born at Altitude

NCT04639583
View directory record Official record
Conditions
Prematurity; Extreme
Interventions
Near-infrared spectroscopy (NIRS) utilization
Device
Lead sponsor
University of New Mexico
Other
Eligibility
0 Hours to 24 Hours
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 13, 2026, 4:28 PM EDT
Active, not recruiting No phase listed Observational

Transcutaneous Carbon Dioxide Monitoring in Neonates Receiving Therapeutic Hypothermia for Neonatal Encephalopathy

NCT04603547
View directory record Official record
Conditions
Neonatal Encephalopathy
Interventions
Transcutaneous Carbon Dioxide Monitoring
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
0 Days to 3 Days
Enrollment
53 participants
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 13, 2026, 4:28 PM EDT
Not listed No phase listed Observational

Multidimensional Classification of Mild Traumatic Brain Injury (mTBI)

NCT04874389
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Multimodal Assessment
Diagnostic Test
Lead sponsor
Clea Tucker
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Timeline
2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Sep 13, 2026, 4:28 PM EDT
Completed No phase listed Observational

RBC Irradiation, Anemia and Gut Injury

NCT02741648
View directory record Official record
Conditions
Anemia, Necrotizing Enterocolitis
Interventions
Near Infrared Spectroscopy, Non-invasive Image-based Anemia Assessment
Device · Other
Lead sponsor
Emory University
Other
Eligibility
1 Day to 5 Days
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 13, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Validation Study of Bioelectronics

NCT05397951
View directory record Official record
Conditions
Healthy, Health Behavior
Interventions
Multi-modality Noninvasive Biosensor, Oximeter, Portable Blood Pressure Monitor, Vicorder Pulse Wave Velocity Monitor
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 13, 2026, 4:28 PM EDT
Recruiting No phase listed Observational

PDA for Kidneys Study

NCT06658496
View directory record Official record
Conditions
Patent Ductus Arteriosus, Congenital Heart Disease
Interventions
Near Infrared Spectroscopy
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
1 Minute to 7 Days
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 13, 2026, 4:28 PM EDT