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ClinicalTrials.gov public records Last synced Nov 15, 2026, 5:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 58 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Near-infrared fluorescence imaging Clear all

Conditions: Intraoperative Ureter Injury
Interventions: Nerindocianine for Injection; Drug
Lead sponsor: Li-Cor, Inc.; Industry
Eligibility: 19 Years and older · Female only
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Intraoperative Ureter Visualization, Abdominolpelvic Surgery
Interventions: pudexacianinium chloride; Drug
Lead sponsor: Astellas Pharma Global Development, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 12
States / cities: Los Angeles, California • Newport Beach, California • Tampa, Florida + 8 more

Conditions: Esophageal Cancer
Interventions: Injection of indocyanine green (ICG)dye, Near-Infrared Image-Guided, Sentinel Lymph Node (SLN) mapping; Other · Device · Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Parathyroid Dysfunction, Adenoma
Interventions: Indocyanine green, SPY Portable Handheld Imaging; Drug · Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 417 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Fibroid Uterus, Endometriosis, Uterus Myoma, Uterine Fibroid, Uterine Adenomyosis, Endometrial Cyst, Uterine Cyst
Interventions: ICG; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Melanoma
Interventions: Indocyanine Green (IC-Green), Imaging; Drug · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Meningioma, Glioblastoma, Acoustic Neuroma, Brain Cancer, Pituitary Adenoma
Interventions: Panitumumab-IRDye800; Drug
Lead sponsor: Eben Rosenthal; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
Interventions: indocyanine green solution, diffuse optical imaging, robot-assisted laparoscopic surgery, therapeutic lymphadenectomy; Drug · Other · Procedure
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years to 80 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Duarte, California

Conditions: Lymphedema
Interventions: Indocyanine Green (ICG), Near-infrared Fluorescence Lymphatic Imaging (NIRFLI); Drug · Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Endometrial Cancer, Near Infrared Fluorescence Imaging, CYTALUX (Pafolacianine) Injection, Planned Diagnostic Laparoscopies
Interventions: CYTALUX™ (pafolacianine), 1788 4K Camera System with Advanced Imaging Modality; Drug · Device
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Neck Pain, Back Pain
Interventions: Indocyanine green (ICG) dye, NIRF-LI imaging, Neuroglide pad; Drug · Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Biliary Atresia, Kasai, Cholestasis in Newborn, Cholestasis in Newborn Infant
Interventions: Indocyanine Green; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 2 Weeks to 4 Months
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Coronary Artery Disease
Interventions: ComboMap XT Guidewire, 'SPY' NIRF During CABG; Device · Procedure
Lead sponsor: East Carolina University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Rheumatoid Arthritis
Interventions: Indocyanine Green, MultiSpectral Imaging System; Drug · Device
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 89 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Rheumatoid Arthritis
Interventions: Indocyanine Green, MultiSpectral Imaging System; Drug · Device
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 89 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Trauma Injury
Interventions: Immunofluorescence Imaging, DCE-MRI; Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 4
States / cities: Irvine, California • Baltimore, Maryland • Boston, Massachusetts + 1 more

Conditions: Solitary Pulmonary Nodules
Interventions: near infrared fluorescence imaging (NIFI), Indocyanine Green; Device · Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Injury of Ureter During Surgery (Disorder)
Interventions: Nizaracianine Triflutate, Placebo Comparator; Drug
Lead sponsor: Curadel Surgical Innovations, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 336 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 5
States / cities: Los Angeles, California • Redwood City, California • Orlando, Florida + 2 more

Conditions: Endometrial Cancer, Uterine Cancer, Cervical Cancer
Interventions: PINPOINT; Device
Lead sponsor: Novadaq Technologies ULC, now a part of Stryker; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 5
States / cities: San Jose, California • Fort Myers, Florida • New York, New York + 2 more

Conditions: Endometrial Cancer, Sentinel Lymph Node Detection
Interventions: ICG Dye; Procedure
Lead sponsor: Lahey Clinic; Other
Eligibility: 18 Years to 90 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Burlington, Massachusetts

Conditions: Breast Cancer
Interventions: NIR Imaging with FLARE and Mini-FLARE Imaging System; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Intraoperative Ureter Visualization, Abdominolpelvic Surgery
Interventions: pudexacianinium chloride; Drug
Lead sponsor: Astellas Pharma Global Development, Inc.; Industry
Eligibility: 12 Years and older
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 6
States / cities: Orlando, Florida • Tampa, Florida • Weston, Florida + 3 more

Conditions: Trauma Injury
Interventions: Immunofluorescence Imaging; Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Ovarian Cancer, Ovarian Carcinoma
Interventions: Intravenous Indocyanine Green/ICG injection, PINPOINT endoscopic fluorescence imaging system, Endoscopy; Diagnostic Test
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: Female only
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 9
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 6 more

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Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery

A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery in People With or Without Kidney Disease

Sentinel Lymph Node Mapping in Esophageal Cancer Using ICG Dye and NIR Imaging

Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation

ICG to Assess Ovarian Perfusion

Nuclear and Near-Infrared (NIR) Imaging in Melanoma

Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures

Diffuse Optical Imaging With Indocyanine Green Solution in Imaging Pelvic Lymph Nodes in Patients With Stage II Prostate Cancer Undergoing Surgery

Lymphatic and Systemic Immunity Changes in Post-radiation Lymphedema Development

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

Near-infrared Fluorescence Lymphatic Imaging Assessment of Lymphatic Response to Pneumatic Back/Neck Lymphatic Drainage Delivered by a Pneumatic Manual Lymphatic Drainage Device

The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis

Correlation Study of Imaging Data Acquired During CABG With Data Acquired in the Cath Lab

NIR Fluorescence Imaging of Lymphatic Transport Using ICG

Near InfraRed Fluorescence Using Indocyanine Green and Magnetic Resonance Lymphography of Lymphatic Transport

ICG Fluorescence Imaging in Post-traumatic Infection

Near Infrared Fluorescence Imaging With Indocyanine Green

Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery

A Study Assessing the Safety and Utility of PINPOINT® Near Infrared Fluorescence Imaging in the Identification of Lymph Nodes in Patients With Uterine and Cervical Malignancies Who Are Undergoing Lymph Node Mapping

Indocyanine Green and Near-infrared Fluorescence Imaging to Detect Sentinel Lymph Nodes in Patients With Endometrial Cancer

Real-Time Near-infrared (NIR) Mapping of Sentinel Lymph Nodes in Breast Cancer

A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery

ICG Fluorescence Imaging in Trauma Patients

A Study of Intra-operative Imaging in Women With Ovarian Cancer