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ClinicalTrials.gov public records Last synced Oct 18, 2026, 11:09 AM EDT

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Showing 1–24 of 811 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Nerve block Clear all
Completed No phase listed Observational

Retrospective Femoral Nerve Block Study

NCT01293136
View directory record Official record
Conditions
Other Reconstructive Surgery
Interventions
Femoral nerve block, Intravenous opioids
Procedure · Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 31, 2012 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Early Phase 1 Interventional

Basivertebral Nerve Block During Vertebral Augmentation: An Alternative Approach to Intraprocedural Pain Management

NCT04774029
View directory record Official record
Conditions
Vertebral Compression, Vertebra Compression Fracture, Vertebral Fracture
Interventions
Basivertebral nerve block, Lidocaine induced basivertebral nerve block
Procedure · Drug
Lead sponsor
Northwell Health
Other
Eligibility
50 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Port Jefferson, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

RCT Superior Hypogastric Block During LH

NCT03283436
View directory record Official record
Conditions
Hysterectomy
Interventions
Bupivacaine Hydrochloride 0.25% Injection Solution
Drug
Lead sponsor
Jon I. Einarsson
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Oct 18, 2026, 11:09 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Continuous Femoral and Tibial Nerve Blocks in TKA Patients

NCT01680692
View directory record Official record
Conditions
Analgesia in Total Knee Arthroplasty
Interventions
Ropivicaine, Continuous Femoral Nerve Catheter, Continuous Tibial Nerve Catheter
Drug · Device
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Not applicable Interventional Results available

Computer Assisted Instrument Guidance (CAIG) for Orthopedic Peripheral Nerve Blocks

NCT02614222
View directory record Official record
Conditions
Peripheral Nerve Blocks
Interventions
Peripheral Nerve Blocks with CAIG
Device
Lead sponsor
Clear Guide Medical
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 18, 2026, 11:09 AM EDT
Recruiting Phase 2 Interventional

Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery

NCT03541928
View directory record Official record
Conditions
High-risk Prostate Cancer, Prostate Cancer
Interventions
HSV-Tk, Valacyclovir, Bicalutamide, Leuprolide Acetate, Brachytherapy, External beam radiotherapy, Radical prostatectomy
Drug · Radiation · Procedure
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 6, 2021 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Phase 4 Interventional Results available

Interscalene Block Versus Superior Trunk Block

NCT03272139
View directory record Official record
Conditions
Joint Disease, Pain, Pain, Acute, Pain, Chronic
Interventions
Bupivacaine, Ultrasound
Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 18, 2026, 11:09 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Comparison of Anesthetic Techniques on Total Hip Arthroplasty

NCT01359865
View directory record Official record
Conditions
Osteoarthritis
Interventions
Lumbar Plexus Block
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Phase 4 Interventional Results available

A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants

NCT00756600
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Regional Anesthesia, General Anesthesia
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 60 Weeks
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
10
States / cities
Aurora, Colorado • Chicago, Illinois • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Oct 18, 2026, 11:09 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

NCT04368364
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Phase 4 Interventional Results available

Ultrasound Guided Trigeminal Nerve Block for Typical or Atypical Facial Pain

NCT02024724
View directory record Official record
Conditions
Typical Facial Pain, Atypical Facial Pain
Interventions
Bupivacaine, Triamcinolone, Dexamethasone
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 18, 2026, 11:09 AM EDT
Not listed Not applicable Interventional

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

NCT01589796
View directory record Official record
Conditions
Abdominal Muscles/Ultrasonography, Adult, Ambulatory Surgical Procedures, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Hernia, Inguinal/Surgery, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions
TAP block
Procedure
Lead sponsor
Stamford Anesthesiology Services, PC
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
2
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 2, 2012 · Synced Oct 18, 2026, 11:09 AM EDT
Not listed Not applicable Interventional

Peripheral Nerve Block Compared to Intra-articular Injection for TAA Post-operative Pain

NCT03674905
View directory record Official record
Conditions
Ankle Arthritis, Ankle Arthropathy
Interventions
Intra-articular injection, Peripheral nerve block
Procedure
Lead sponsor
Slocum Research & Education Foundation
Other
Eligibility
40 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 18, 2018 · Synced Oct 18, 2026, 11:09 AM EDT
Terminated Phase 1 Interventional Results available

Stellate Ganglion Blockade in Corona Virus 2019 (COVID-19) Positive Patients

NCT04445337
View directory record Official record
Conditions
COVID 19, ARDS
Interventions
Stellate Ganglion Block
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 18, 2026, 11:09 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Endothelial Hyperpolarization in Humans

NCT00166166
View directory record Official record
Conditions
Hyperlipidemia
Interventions
Tetraethylammonium (TEA), L-NG-monomethyl Arginine (L-NMMA), Bradykinin, Sodium nitroprusside, Acetylcholine, Saline, Fluconazole
Drug
Lead sponsor
Emory University
Other
Eligibility
21 Years to 65 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Liposomal Bupivacaine in Total Shoulder Arthroplasty

NCT02570022
View directory record Official record
Conditions
Pain
Interventions
Liposomal bupivacaine, Inter-scalene nerve block, Ropivacaine
Drug · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 13, 2016 · Synced Oct 18, 2026, 11:09 AM EDT
Withdrawn Not applicable Interventional

High Ankle Block Versus Regional Block for Acute Pain Control After Ankle Surgery

NCT03894098
View directory record Official record
Conditions
Ankle Surgery
Interventions
Nerve block
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2022 · Synced Oct 18, 2026, 11:09 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty

NCT02904993
View directory record Official record
Conditions
Degenerative Joint Disease
Interventions
L2 paravertebral block, periarticular injection group
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 16, 2016 · Synced Oct 18, 2026, 11:09 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures

NCT03651804
View directory record Official record
Conditions
Vertebral Compression Fracture, Facet Joint Pain
Interventions
Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates, Acetaminophen, Physical therapy, Opioids
Procedure · Drug · Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 18, 2026, 11:09 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Use of Lumbar Erector Spinae Plane Block for Hip Arthroplasty at the L4 Interspace

NCT03801863
View directory record Official record
Conditions
Hip Arthropathy, Regional Anesthesia
Interventions
Ultrasound-guided Erector Spinae Plane Block with Ropivacaine 0.375%, Ropivacaine
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Not applicable Interventional Results available

Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery

NCT02219087
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Liposomal bupivacaine, Standard of Care
Drug
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 18, 2026, 11:09 AM EDT
Not yet recruiting Not applicable Interventional

FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy

NCT07637370
View directory record Official record
Conditions
Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
Interventions
Intercostal Nerve Cryoablation
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
40 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Liposomal Bupivacaine Versus Interscalene Nerve Block

NCT03929146
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Exparel, Interscalene Nerve Block
Drug · Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 18, 2026, 11:09 AM EDT
Completed Not applicable Interventional

Supraclavicular Block vs Retroclavicular Block: Incidence of Phrenic Nerve Paralysis

NCT02631122
View directory record Official record
Conditions
Phrenic Nerve Paralysis
Interventions
Supraclavicular vs Retroclavicular Nerve Block
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Oct 18, 2026, 11:09 AM EDT