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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Neural Ice Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

NCT05379959
View directory record Official record
Conditions
Stimulant Use, MDMA ('Ecstasy'), Social Behavior, Motivation
Interventions
MDMA, Methamphetamine, placebo oral tablet
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Sep 8, 2026, 5:53 PM EDT
Completed No phase listed Observational

Clinical Correlates of Pressure Pain Thresholds in Back and Leg Pain

NCT06653920
View directory record Official record
Conditions
Segmental Dysfunction of the Lumbar Spine, Back Pain, Leg Pain
Interventions
Chiropractic, Exercise, Cryotherapy, Spinalator
Other · Device
Lead sponsor
Leach Chiropractic Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 8, 2026, 5:53 PM EDT
Active, not recruiting Not applicable Interventional

INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE

NCT06700109
View directory record Official record
Conditions
Osteoarthritis (OA) of the Knee
Interventions
Neural Ice, Triamcinolone acetate
Device · Drug
Lead sponsor
Brixton Biosciences, Inc.
Industry
Eligibility
22 Years to 80 Years
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
15
States / cities
Larkspur, California • Washington D.C., District of Columbia • Gainesville, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 8, 2026, 5:53 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Interactive Physical and Cognitive Exercise System

NCT03069391
View directory record Official record
Conditions
Alzheimer Disease, Early Onset, MCI, Aging, Mild Cognitive Impairment, Neurocognitive Disorder, Cognitive Impairment, Cognitive Change
Interventions
physical exercise alone (PES) first, cognitive exercise alone (iCE) first, interactive Physical and Cognitive Exercise (iPACES™)
Behavioral · Device
Lead sponsor
Union College, New York
Other
Eligibility
50 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Schenectady, New York
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 8, 2026, 5:53 PM EDT
Recruiting Not applicable Interventional

Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

NCT04996628
View directory record Official record
Conditions
Chronic Pancreatitis, Chronic Pain
Interventions
Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 8, 2026, 5:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Mechanisms of Cost and Benefit Integration During Decision-Making, Aim 2: Acute & Lifetime Stress

NCT04060966
View directory record Official record
Conditions
Healthy
Interventions
Cold-Pressor Task (CPT), Control CPT, fMRI
Behavioral · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 64 Years
Enrollment
397 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Sep 8, 2026, 5:53 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Aldosterone & Sodium Regulation in Postural Tachycardia Syndrome - Screening

NCT01783288
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Autonomic Function Testing, Posture Study, Measurement of Total Blood Volume, Exercise Capacity Test
Other · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 8, 2026, 5:53 PM EDT
Enrolling by invitation Phase 2 Interventional

An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder

NCT07693608
View directory record Official record
Conditions
Obesity, Methamphetamine Use Disorder, Cocaine Use Disorder, Stimulant Use Disorders
Interventions
Tirzepatide
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 8, 2026, 5:53 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Pancreatic Quantitative Sensory Testing (P-QST)

NCT06996535
View directory record Official record
Conditions
Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
Interventions
Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
Diagnostic Test
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Sep 8, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neural Control of Kidney Blood Flow During Exercise in African American Adults

NCT03981640
View directory record Official record
Conditions
Healthy
Interventions
Acute exercise, Cold pressor test, Mental stress test
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years to 35 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 8, 2026, 5:53 PM EDT
Completed Early Phase 1 Interventional

Exercise in Methamphetamine Use Disorder Upregulation and Neural Function

NCT03709667
View directory record Official record
Conditions
Methamphetamine Abuse
Interventions
EX, CON
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Sep 8, 2026, 5:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

NCT03434392
View directory record Official record
Conditions
Chronic Pancreatitis, Chronic Pain
Interventions
Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
Diagnostic Test
Lead sponsor
Anna Evans Phillips
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 8, 2026, 5:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Stress on Encoding and Prediction

NCT05920161
View directory record Official record
Conditions
Stress, Learning, Spatial
Interventions
Socially Evaluated Cold Pressor Test, Control
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 8, 2026, 5:53 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Kidney Blood Flow During Exercise in Older African American Adults

NCT07029165
View directory record Official record
Conditions
Healthy
Interventions
Acute exercise, Cold pressor test, Mental stress test
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
55 Years to 79 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 8, 2026, 5:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Stress & Self-Control Costs

NCT05795179
View directory record Official record
Conditions
Self-Control
Interventions
Cold-Pressor Task (CPT), Trier Social Stress Test (TSST), Modified Non-Stress CPT, Modified Non-Stress TSST, Functional Magnetic Resonance Imaging (fMRI)
Behavioral · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 8, 2026, 5:53 PM EDT