Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 3, 2026, 9:47 AM EDT

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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Conditions
Clinical High Risk for Psychosis
Interventions
Targeted Cognitive Training, Computer Games
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
15 Years to 30 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting No phase listed Observational Accepts healthy volunteers

Brain Health in Transgender Adults

NCT07624747
Conditions
Gender Dysphoria
Interventions
Magnetic Resonance Imaging, Cognition and Health Tests, Optional Exercise Test
Device · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Acute Myelogenous Leukemia, Myelodysplastic Syndrome
Interventions
Questionnaire, Neurocognitive Testing
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Houston, Texas
Conditions
Cocaine Dependence
Interventions
Zonisamide, Placebo, Cocaine Hydrochloride, Neurocognitive and Performance Battery, Smoking Assessments
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 45 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Opioid Use Disorder
Interventions
Neurocognitive battery, fNIRS
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
192 participants
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Parkinson Disease
Interventions
MultiContext for PD Strategy Training, Standard of Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Opioid-use Disorder, Amphetamine Use Disorders
Interventions
Neurocognitive Empowerment for Addiction Treatment (NEAT), Active Control
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Recruiting Not applicable Interventional

Neural Basis of Human Working Memory

NCT07617506
Conditions
Memory Disorders
Interventions
Neurocognitive Tasks, Ripple Neuromed Summit System
Behavioral · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Amnestic Mild Cognitive Impairment
Interventions
Cognitive Training, Computerized Cognitive Stimulation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 100 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Congenital Heart Disease, Neurodevelopment, Executive Function, Working Memory Training, Infant Open-heart Surgery
Interventions
Cogmed Working Memory Training
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
13 Years to 16 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional

Cognitive Remediation

NCT07171450
Conditions
Aging, Inflammation, Cognitive Remediation, Cognitive Dysfunction, Postviral Syndrome, Digital Medicine
Interventions
Computerized Cognitive Remediation, Alternative Computer Activities
Other
Lead sponsor
Cutter Lindbergh
Other
Eligibility
60 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Bipolar Disorder
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
7 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neurocognitive Predictors of Health Risk Behaviors

NCT06941181
Conditions
Substance Use
Interventions
neurocognitive tasks
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2029
U.S. locations
2
States / cities
Blacksburg, Virginia • Roanoke, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Youth Soccer Header Study

NCT04919707
Conditions
Brain Injuries
Interventions
Header Session, MRI Session
Behavioral · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
12 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder, Healthy
Interventions
Not listed
Lead sponsor
Bradley Hospital
Other
Eligibility
7 Years to 17 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2018
U.S. locations
1
States / cities
East Providence, Rhode Island
Conditions
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Phase 3 Interventional Accepts healthy volunteers

Biomarker Exploration in Aging, Cognition and Neurodegeneration

NCT03860857
Conditions
Alzheimer Disease, Cognitive Impairment, Cognitive Decline
Interventions
Amyloid PET scan, Tau PET scan using MK-6240, Neurocognitive testing, MRI
Radiation · Drug · Behavioral + 1 more
Lead sponsor
University of California, Irvine
Other
Eligibility
60 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Irvine, California
Conditions
Chronic Ankle Instability
Interventions
Neurocognitive Ankle Training for Instablity to Optimize Neuromusculoskeletal outcomes (NATION), Evidence-Based
Other
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 44 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Lexington, Kentucky • Fort Bragg, North Carolina
Conditions
Congenital Heart Defect, Executive Function, Children, Neurodevelopmental Disorders, Working Memory, Infant Open Heart Surgery
Interventions
Cogmed Working Memory Training
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years to 12 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Subjective Cognitive Complaints, Ehlers-Danlos Syndrome, Cognitive Dysfunction
Interventions
COG+OT Telerehabilitation
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Charleston, South Carolina
Conditions
Lysosomal Diseases, Gangliosidosis, GM1
Interventions
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
Biological · Procedure · Drug + 3 more
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
6 Months to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Terminated Not applicable Interventional Accepts healthy volunteers

FITLIGHT Reliability and Acute Training Effects

NCT06748417
Conditions
Athletic Injuries
Interventions
Acute Cognitive Training, Non-stimulating Rest
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 25 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Coral Gables, Florida
Completed No phase listed Observational Accepts healthy volunteers

Field Implementation of iDETECT

NCT02529618
Conditions
Concussion, Brain Trauma
Interventions
integrated Display Enhanced Testing for Cognitive Impairment and mild traumatic brain injury (iDETECT), Riddell High Impact Technology (HIT) System, i1 Biometrics Vector Mouth Guard
Device
Lead sponsor
Emory University
Other
Eligibility
14 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
4
States / cities
Atlanta, Georgia • College Park, Georgia • Marietta, Georgia + 1 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neurocognitive Factors in EdTech Intervention Response

NCT04568824
Conditions
Reading Disability
Interventions
GraphoLearn reading intervention, Vektor math control intervention
Other
Lead sponsor
University of Connecticut
Other
Eligibility
6 Years to 10 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New York, New York