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Conditions: Hunter Syndrome
Interventions: Neurobehavioral testing, Visual and auditory assessments; Behavioral · Other
Lead sponsor: Shire; Industry
Eligibility: 32 Months to 18 Years · Male only
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Hypoxic-Ischemic Encephalopathy, Hypoglycemia, Neonatal Abstinence Syndrome
Interventions: nfant feeding solution; Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: Up to 6 Months
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Premature Birth, Neurodevelopmental Disorders, Brain Development Abnormality, Brain Lesion
Interventions: MRI, Neurodevelopmental/Neuropsychological Assessment; Diagnostic Test
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: Up to 8 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Lyme Disease, Post-Treatment Lyme Disease, Chronic Lyme Disease, Tick-Borne Infections, Pregnancy Complications, Child Development
Interventions: Neurodevelopmental assessments and follow-up; Other
Lead sponsor: Children's National Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: DDX3X, Mental Retardation, X-linked 102, Autism Spectrum Disorder
Interventions: Not listed
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 2 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Congenital Heart Disease
Interventions: Not listed
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 1 Day to 2 Months
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Zika Virus, Congenital Zika Syndrome, Congenital Infection, Child Development
Interventions: Neurodevelopmental assessments; Other
Lead sponsor: Children's National Research Institute; Other
Eligibility: 3 Years to 7 Years
Enrollment: 204 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: ADNP, Helsmoortel-Van Der Aa Syndrome, Autism Spectrum Disorder
Interventions: Not listed
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 2 Years and older
Enrollment: 30 participants
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Bilirubin Encephalopathy
Interventions: usual prescribed intralipid (UL) regimen, restricted prescribed intralipid (RL) regimen; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: Up to 27 Weeks
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Family Relations, Nutrition Disorders, Health Behavior, Transgenderism
Interventions: Survey; Other
Lead sponsor: St. Louis University; Other
Eligibility: 12 Years and older
Enrollment: 714 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Cerebral Visual Impairment
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 6 Months to 72 Months
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Prematurity Complications, NICU Infants, Early Intervention, Telehealth
Interventions: Baby Bridge; Other
Lead sponsor: University of Southern California; Other
Eligibility: Up to 6 Months
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder), Cerebral Palsy (CP), Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment, Cerebral Palsy Infantile, Cerebral Palsy Spastic Hemiplegic, Cerebral Palsy, Dyskinetic, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD, Hypoxic Ischemic Encephalopathy, Hypoxic Ischemic Encephalopathy (HIE), Traumatic Brain Injury (TBI), Sensory Processing Disorder, Chromosomal Abnormalities, Genetic Disorders, Down Syndrome (Trisomy 21), Fragile X Syndrome (FXS), RETT Syndrome With Proven MECP2 Mutation, Williams Syndrome, 22q11.2 Deletion Syndrome, Sensorimotor Integration
Interventions: Not listed
Lead sponsor: Healing Hope International; Other
Eligibility: 4 Years to 12 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2036
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Prematurity
Interventions: Ultrasound; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 2 Years to 4 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Autism Spectrum Disorder, Neurodevelopmental Disorders
Interventions: Parents and Infants Engaged; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 11 Months to 16 Months
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Epilepsy, Seizure, Cognition Disorders
Interventions: Differential Abilities Scale, Neuropsychological Testing; Behavioral
Lead sponsor: Emory University; Other
Eligibility: Female only
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2012
U.S. locations: 20
States / cities: Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 17 more

Conditions: Infant Development, Cerebral Palsy, Motor Disorders, Neurological Disorder
Interventions: Observational; Other
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 10 Weeks to 20 Weeks
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Autism
Interventions: Eyelink Portable Duo, Integrated PCP Diagnosis and Eye-tracking Biomarker; Diagnostic Test
Lead sponsor: Indiana University; Other
Eligibility: 14 Months to 48 Months
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 7
States / cities: Anderson, Indiana • Batesville, Indiana • Indianapolis, Indiana + 4 more

Conditions: Autistic Disorder, Autism Spectrum Disorder, Asperger Syndrome, Pervasive Developmental Disorder
Interventions: Cognitive Enhancement Therapy, Enriched Supportive Therapy; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 16 Years to 45 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Autism Spectrum Disorders, Seizures
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 1 Year to 7 Years
Enrollment: 557 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: FOXP1, Mental Retardation With Language Impairment and With or Without Autistic Features, Autism Spectrum Disorder
Interventions: Not listed
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 2 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Congenital Heart Defect, Executive Function, Children, Neurodevelopmental Disorders, Working Memory, Infant Open Heart Surgery
Interventions: Cogmed Working Memory Training; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 7 Years to 12 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Rett Syndrome
Interventions: TSHA-102; Genetic
Lead sponsor: Taysha Gene Therapies, Inc.; Industry
Eligibility: 2 Years to 3 Years · Female only
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 3
States / cities: Birmingham, Alabama • Chicago, Illinois • Boston, Massachusetts

Conditions: Schizophrenia
Interventions: Cognitive Enhancement Therapy, Enriched Supportive Therapy; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 60 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

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Screening Study to Identify Pediatric Patients With Hunter Syndrome Who Demonstrate Evidence of Central Nervous System (CNS) Involvement and Who Are Currently Receiving Treatment With Elaprase®

Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk

Childhood Outcomes of Preterm Brain Abnormalities

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

Use of AEEG as Predictor of Long-term Motor Outcome in Neonates With Congenital Heart Disease

Neurodevelopmental Outcomes in ZIKV-Exposed Children

ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

Bilirubin Neurotoxicity (BN) and Neurodevelopmental Impairment (NDI) in Extremely Preterm (EP) Infants: Avoidable by Reducing the Usual Intravenous Lipid (UL) Administration

Family Relationships and Nutrition in TGGD Youth and Young Adults

Neurodevelopmental Outcomes in Cerebral Visual Impairment

A Pilot Study Comparing Telehealth and In-Person Therapy Service Delivery Following NICU Discharge

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

Ultrasound, Peds Body Composition, and Neurodevelopmental Outcomes

Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders

Developmental Effects On Children Of Women Who Take Antiepileptic Drugs During Pregnancy

Families Filming Infants Learning Movement

Validation of Indiana's Early Evaluation Hub System

Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

Clinical and Immunological Investigations of Subtypes of Autism

FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study

Safety and Preliminary Efficacy of TSHA-102 Gene Therapy in Pediatric Females Aged >2 to <4 Years With Rett Syndrome

Promoting Activity and Cognitive Enrichment in Schizophrenia (PACES)