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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Neurofeedback Intervention Clear all
Recruiting Not applicable Interventional

Amygdala Neurofeedback for Depression - Large Scale Clinical Trial

NCT05703256
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Amygdala real-time fMRI neurofeedback, Sham feedback
Device
Lead sponsor
Kymberly Young
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Not listed Not applicable Interventional

Using Mobile Devices for Neurofeedback to Reduce Opioid Use in Chronic Pain

NCT04838925
View directory record Official record
Conditions
Chronic Pain, Opioid Use
Interventions
Mobile Neurofeedback App
Device
Lead sponsor
CrossComm, Inc.
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2023 · Synced Sep 14, 2026, 1:10 PM EDT
Active, not recruiting Phase 2 Interventional

Interdisciplinary Interventions to Address Pain Management Among Head and Neck Cancer Patients

NCT05077072
View directory record Official record
Conditions
Head and Neck Carcinoma
Interventions
Best Practice, Counseling, Electroencephalography, Neurofeedback, Questionnaire Administration
Other · Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Comparing Real-time fMRI Neurofeedback Versus Sham for Altering Limbic and Eating Disturbances in Anorexia Nervosa

NCT04220112
View directory record Official record
Conditions
Anorexia, Anorexia Nervosa
Interventions
Real-Time Functional Magnetic Resonance Imaging (RT-fMRI), Sham Procedure
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 30, 2022 · Synced Sep 14, 2026, 1:10 PM EDT
Terminated Not applicable Interventional

Train Your Brain: Neurofeedback Intervention for PTSD

NCT03858933
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
eBrainFit Platform
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2021 · Synced Sep 14, 2026, 1:10 PM EDT
Recruiting Not applicable Interventional

A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder

NCT05621538
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Realtime fMRI Neurofeedback - Active, TMS - Active, Realtime fMRI Neurofeedback - Yoked Sham, TMS - Sham
Behavioral · Device
Lead sponsor
Auburn University
Other
Eligibility
19 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 14, 2026, 1:10 PM EDT
Recruiting Not applicable Interventional

Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

NCT06109909
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Photophobia
Interventions
Micro Current Neurofeedback Device using Low-Frequency Pulse-Based Transcranial Electrical Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Responsiveness to Acute Changes in Exercise and Relaxation (RACER) Trial

NCT03702712
View directory record Official record
Conditions
Breast Cancer
Interventions
Aerobic Exercise and Relaxation, Aerobic Exercise Only, Relaxation Only
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics

NCT02766374
View directory record Official record
Conditions
Asthma
Interventions
Heart rate variability biofeedback, Placebo
Behavioral
Lead sponsor
Fred Wamboldt, MD
Other
Eligibility
18 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2018
U.S. locations
2
States / cities
Denver, Colorado • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Sep 14, 2026, 1:10 PM EDT
Not yet recruiting Not applicable Interventional

Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa

NCT07581158
View directory record Official record
Conditions
Bulimia Nervosa, Feeding and Eating Disorders, Mental Disorders
Interventions
Real fNIRS Neurofeedback, Sham-Control fNIRS Neurofeedback, SmartPhone Intervention
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Neurofeedback Technology (GZNT) for Persistent Post-Concussive Symptoms in Soldiers

NCT02509689
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Global Z-Score Neurofeedback Training
Behavioral
Lead sponsor
The Defense and Veterans Brain Injury Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Fort Carson, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 3, 2022 · Synced Sep 14, 2026, 1:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mobile Neurofeedback for Low Back Pain

NCT05669027
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Neurofeedback, Sham (Placebo Control)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 14, 2026, 1:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurofeedback Intervention for Reading Deficits in Subacute Stroke

NCT04875936
View directory record Official record
Conditions
Stroke, Dyslexia, Acquired
Interventions
Motor Imagery and Real-Time fMRI Neurofeedback, Motor Imagery and Sham fMRI Neurofeedback
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Not listed Not applicable Interventional

Effectiveness of EEG Neurofeedback in Pediatric Occupational Therapy to Improve Executive Functioning

NCT04221620
View directory record Official record
Conditions
Executive Functioning, Pediatric ALL
Interventions
Zengar Electroencephalogram (EEG) Neurofeedback device
Device
Lead sponsor
Northern Arizona University
Other
Eligibility
6 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Prescott, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 8, 2020 · Synced Sep 14, 2026, 1:10 PM EDT
Not listed Not applicable Interventional

Restoring Grasp Ability in Stroke Survivors Through MI-Based Training

NCT06307834
View directory record Official record
Conditions
Stroke
Interventions
Neurofeedback - based therapy, Standard hand exercise therapy
Behavioral
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 14, 2026, 1:10 PM EDT
Active, not recruiting Not applicable Interventional

An Intervention to Enhance Well-Being in Trauma Exposed New Mothers

NCT05474534
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Dissociation, Maternal Care Patterns, Infant Behavior, Maternal Behavior, Maternal Distress, Mood Disturbance, Emotional Regulation
Interventions
Neurofeedback (MUSE 2)
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Mindfulness Surgical Pain Outcomes

NCT05838443
View directory record Official record
Conditions
Post Surgical Pain, Surgery
Interventions
Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 18 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional Results available

Neurofeedback Impact on Veterans With mTBI

NCT04195685
View directory record Official record
Conditions
Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache, Chronic Insomnia, Chronic Attention Disorder
Interventions
Neurofeedback (NFB)
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional

The Diagnosis and Incidence of Critical Illness Polyneuromyopathy in Medical and Neurosurgical ICU Patients

NCT02634658
View directory record Official record
Conditions
Critical Illness
Interventions
Muscle Ultrasound, Nerve Conduction Study, Electromyography
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Sep 14, 2026, 1:10 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.

NCT07214974
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis, Alzheimer's Disease and Related Dementias, Parkinson's Disease, Parkinson's Disease (PD), Parkinson's Disease With Wearing-off Motor Fluctuations, Dementia (Diagnosis), Dementia MCI (Mild Cognitive Impairment)
Interventions
Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental, Control - Placebo Comparator
Behavioral · Device · Biological + 1 more
Lead sponsor
Noah Tech, Corp.
Industry
Eligibility
55 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palisades Park, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mindful Minds: Mindfulness-Based Neurofeedback for Underrepresented College Students

NCT06784934
View directory record Official record
Conditions
Academic Performance, Anxiety
Interventions
NeuroSky Mindfulness-Based Neurofeedback
Device
Lead sponsor
Florida International University
Other
Eligibility
18 Years to 30 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Terminated Not applicable Interventional Results available

Neurofeedback in Individuals With Substance Use Disorders

NCT04188288
View directory record Official record
Conditions
Opioid-Related Disorders
Interventions
Experimental feedback, Control feedback, fMRI
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Sep 14, 2026, 1:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Training Upper Limbs of Neurodiverse Children by Connecting Brain Activities to a Virtual Reality Based Game

NCT06818877
View directory record Official record
Conditions
Healthy Children, CP (Cerebral Palsy), CP, Cerebral Palsy
Interventions
Brain-Computer Interface (BCI)-HABIT-VR, Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR)
Device
Lead sponsor
University of Nebraska
Other
Eligibility
6 Years to 17 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 14, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Effects of Memory Boot Camp on Brain Function in Adults With Symptoms of Mild Cognitive Impairment (MCI)

NCT04426162
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Multi-domain Intervention
Other
Lead sponsor
Neurocore
Other
Eligibility
55 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
3
States / cities
Boca Raton, Florida • Palm Beach Gardens, Florida • Grandville, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Sep 14, 2026, 1:10 PM EDT