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ClinicalTrials.gov public records Last synced Oct 26, 2026, 5:08 AM EDT

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Showing 433–456 of 732 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Neuromodulation Clear all
Terminated Phase 2Phase 3 Interventional

The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition

NCT03693105
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
Interventions
Active SAINT Stimulation, Sham SAINT Stimulation
Device
Lead sponsor
Magnus Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Iowa City, Iowa • Manhattan, New York • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 26, 2026, 5:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhanced Gait and Balance Training

NCT01896466
View directory record Official record
Conditions
Aging, Accidental Falls
Interventions
Cranial Nerve Non-Invasive Neuromodulation, Sham Cranial Nerve Non-Invasive Neuromodulation
Device · Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 95 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 26, 2026, 5:08 AM EDT
Active, not recruiting No phase listed Observational

Portable Neuromodulation Stimulator Registry for People With Multiple Sclerosis

NCT06930339
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Portable Neuromodulation Stimulator (PoNS)
Device
Lead sponsor
Helius Medical Inc
Industry
Eligibility
22 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Newtown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 26, 2026, 5:08 AM EDT
Enrolling by invitation Not applicable Interventional

Adaptive Deep Brain Stimulation for Freezing of Gait in Parkinson's Disease

NCT06819020
View directory record Official record
Conditions
Parkinson Disease
Interventions
Percept RC
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
21 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Reboot Pain (tDCS)

NCT07411859
View directory record Official record
Conditions
Chronic Pain
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management

NCT07160049
View directory record Official record
Conditions
Pain Management, Peripheral Neuropathic Pain
Interventions
Cold Pressor Task - Upper Limb, Algometry Pain Tests in the Upper Limb, Algometry Pain Tests in the Lower Limb
Device
Lead sponsor
Evan (Huiliang) Wang
Other
Eligibility
20 Years to 40 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Study of Low-intensity Focused Ultrasound Effects on Human Memory

NCT06628193
View directory record Official record
Conditions
Memory
Interventions
Low intensity focused ultrasound, Sham (No Treatment)
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Not listed Not applicable Interventional

Translumbosacral Neuromodulation for FI

NCT03899181
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Translumbosacral Neuromodulation Therapy (TNT), Sham TNT Therapy
Device · Other
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Augusta, Georgia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 26, 2026, 5:08 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty (TKA) Using the SPRINT System

NCT02468934
View directory record Official record
Conditions
Total Knee Replacement, Total Knee Arthroplasty, Pain, Postoperative Pain, Orthopedic Disorders
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
La Jolla, California • Durham, North Carolina • New Albany, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Oct 26, 2026, 5:08 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Noninvasive Spinal Neuromodulation Enables Locomotor Recovery in Individuals With Cerebral Palsy

NCT04882592
View directory record Official record
Conditions
Cerebral Palsy
Interventions
SCiP
Device
Lead sponsor
SpineX Inc.
Industry
Eligibility
2 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

NCT05725499
View directory record Official record
Conditions
Spinal Cord Injuries, Hypotension, Orthostatic Hypotension, Spinal Cord Diseases, Cardiovascular Diseases, Trauma, Nervous System, Central Nervous System Diseases, Nervous System Diseases, Blood Pressure
Interventions
Biostim-5 transcutaneous spinal stimulator, Tilt-table orthostatic stress testing
Device · Diagnostic Test
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Deep Brain Stimulation for Psychosis

NCT06257056
View directory record Official record
Conditions
Treatment-Refractory Schizophrenia
Interventions
Abbott Laboratories Infinity™ implantable deep brain stimulation system
Device
Lead sponsor
Bradley Lega
Other
Eligibility
22 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

NCT06213012
View directory record Official record
Conditions
Spinal Cord Injuries, Neuromodulation
Interventions
Transcutaneous Spinal cord Stimulation, Epidural Spinal Stimulation (ESS)
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
22 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Completed Not applicable Interventional Results available

Exploring the Use of Non-invasive Neuromodulation Combined With Exercise in People With Advanced Multiple Sclerosis (MS)

NCT02252666
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Neuromodulation Rehabilitation
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study

NCT07517172
View directory record Official record
Conditions
Temporomandibular Disorder
Interventions
Transcutaneous Auricular Neurostimulation, Sham Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Completed Not applicable Interventional

Vestibulopathy, Imbalance, and Gait Disturbances in Parkinson Disease

NCT05446194
View directory record Official record
Conditions
Parkinson Disease
Interventions
Non invasive neuromodulation device pattern 1, Non invasive neuromodulation device pattern 2
Device
Lead sponsor
University of Michigan
Other
Eligibility
45 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Completed Not applicable Interventional Results available

Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome

NCT04428619
View directory record Official record
Conditions
Irritable Bowel Syndrome, Abdominal Pain, Autonomic Nervous System Imbalance
Interventions
Peripheral Electrical Nerve Field Stimulation (PENFS) Device, Sham Device
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 26, 2026, 5:08 AM EDT
Terminated Phase 1Phase 2 Interventional

Ultrasonic Neuromodulation for Treatment of PTSD

NCT06135064
View directory record Official record
Conditions
PTSD
Interventions
Diadem
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 26, 2026, 5:08 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Imaging Brain Fluids During Breathing

NCT05180981
View directory record Official record
Conditions
Healthy
Interventions
Transcutaneous vagal nerve stimulation, Breathing task
Device · Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 70 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Active, not recruiting Not applicable Interventional

Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease

NCT04675398
View directory record Official record
Conditions
Parkinson Disease
Interventions
Summit RC+S
Device
Lead sponsor
Doris Wang, MD, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Completed Not applicable Interventional Results available

Non-invasive Intervention for Apnea of Prematurity

NCT02641249
View directory record Official record
Conditions
Apnea of Prematurity, Hypoxia, Bradycardia
Interventions
Vibration
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
1 Week and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke

NCT07404852
View directory record Official record
Conditions
Large Vessel Occlusion, Acute Ischemic Stroke
Interventions
transcutaneous auricular vagal nerve stimulation, Sham transcutaneous vagal nerve stimulation
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 99 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional

Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment

NCT02916810
View directory record Official record
Conditions
Schizophrenia and Related Disorders
Interventions
Active rTMS stimulation, Sham rTMS stimulation
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 26, 2026, 5:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury

NCT05762796
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
Interventions
tDCS in Youth with mild traumatic brain injury
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 26, 2026, 5:08 AM EDT